E. Cobham Brewer 18101897. Dictionary of Phrase and Fable. 1898.
Anodyne Necklace (An),
a halter. An anodyne is a medicine to relieve pain. Probably a pun on nodus, a knot, is intended also. George Primrose says: May I die by an anodyne necklace, but I had rather be an under-turnkey than an usher in a boarding-school.