Ebola Virus Disease

In late 2013, Ebola virus disease (EVD), a deadly and lethal disease, remerged in West Africa spreading to various countries in the region. In humans, the disease is spread through contact with infected bodily fluids leading to haemorrhagic fever (World Health Organization [WHO], 2015). Originating in 1976 in equatorial Africa, past outbreaks with a few hundred cases had been contained within rural, forested areas in Uganda and Congo (Piot, 2012). In 2014, a total of 20, 206 cases and 7,905 deaths were reported to have occurred in up to eight countries worldwide. Of all cases and deaths resulting from the disease, 99.8% occurred in three neighbouring West African countries - Liberia, Sierra Leone and Guinea (WHO, 2014). With a case fatality rate from about 50% to 90%, and the absence of preventative or curative therapies, the Ebola epidemic has led to overall global alarm and further elucidated existing global health disparities that perpetuated the epidemic with these West African countries.

In 2014, Ebola hemorrhagic fever caused an outbreak in West Africa that officially ended in 2016. The Centers for Disease Control and Prevention (CDC) says, “Ebola is a rare and deadly disease caused by infection with one of the Ebola virus species” (“Ebola (Ebola Virus Disease)”). Ebola is caused when a person is in contact with an infected person’s blood or other body fluids. Prevention of contracting the disease include, not touching the dead body of an infected person, not touching body fluids of an infected person, avoiding places infected people are being treated, not touching bats or nonhuman primates

Although Ebola caught the world’s attention during the 1995 outbreak in Zaire, the first outbreak occurred in 1976. As the chart below displays, 71% of the people infected died as a result of Ebola during this first outbreak (Bulletin of the World Health Organization, 56 (2): 247-270, 1978). With the current outbreak, this ratio has dramatically decreased as a result of scientific research leading to early detection, but the current infected population is more than 20 times the amount of any previous outbreak and this number continues to grow as no vaccine exists to prevent the disease.

Ebola was first recognized in 1976 as the cause of outbreaks of disease in the Democratic Republic of the Congo (then known as Zaire) and in Sudan. About three hundred people in each of the two nations were infected with the virus, resulting in a mortality rate of 88% in Zaire, and 53% in Sudan (Bulletin of the WHO 1978). The disease as it was discovered spread through direct contact of unmans to humans, and then thought, from non-human primates to humans. The epidemic was a result of unsafe and unsanitary hospital practices, and non-sterilized medical equipment. The disease was then contained, however sporadic outbreaks of the Zaire and Sudan Ebola subtypes have risen in the Democratic Republic of the Congo, Gabon, Uganda, and Sudan; one of the latest outbreaks was in the Democratic Republic of the Congo in September of 2007.

The standard treatment for Ebola is still limited to supportive therapy as no vaccines are yet available for clinical use. The supportive therapy consists of balancing the patient’s fluids and electrolytes, maintaining the patient’s oxygen status and blood pressure, and treating the patient for any complicating infections. Treatment from the day the virus is contracted is important but extremely challenging due to the fact that Ebola is very difficult to diagnose in its early stages of infection. However, if a person has the early symptoms of Ebola and there is reason to believe that Ebola should be considered it is extremely important that the patient is isolated

Ebola Virus is a serious transmitted disease by both humans and animals. The disease first appeared in 1976 in 2 simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo. The latter occurred in a village near the Ebola River, from which the virus received its name. Ebola Virus is a member of the negative stranded RNA viruses known as filoviruses. There are currently, five different strains of the Ebola Virus including, Zaire (EBOV), Sudan (SUDV), Bundibuguyo (BDBV), Taï Forest (TAFV) and Reston (RESTV). Each of the strains of the virus are very closely related including Reston which only effects animals. Yet, Ebola Zaire is the most highly virulent subtype, often leading to death. All of the different types of the virus are extremely dangerous and often cause death if untreated.

Ebola Virus disease (EVD) is a severe and often fatal illness in humans according to the World Health Organisation (WHO) (WHO, 2016). Although initially originating in wild animals it spreads through the human population via human to human transmission of bodily fluids with the average casualty rate being about 50% (WHO, 2016). The key to prevention and control of Ebola outbreaks is through community engagement, safe burials and good health centre prevention measures (WHO, 2015). Two countries will be examined one has experienced multiple cases of Ebola, Sierra Leone, and the other a few cases, the United States of America. The

Ashton Nicholas SPC 205 Informative Speech Outline Ebola Virus General Purpose: To inform. Specific Purpose: To explain to my audience research and facts about what Ebola is, what the symptoms and treatments are, how Ebola is spread, and where Ebola is in the world today. Central Idea: Research is helping us to discover and learn all the facts about Ebola. Introduction I. Attention-Getter:

Ebola is the global killer and communicable disease of the world with 69 % case fatality rate, whereas only Zaire strain virus has 90% case fatality rate. It attacks Guinea, Liberia, Sierra Leone, especially the west African’s region as

Prevention of the Ebola virus is more useful than the treatments. Improving sanitation is an important thing to do in rural African countries. Any victims need to be isolated as soon as possible. Quarantining of infected people from others plays a major role. People who have been in close contact with the infected

This viral disease is very rare which causes severe bleeding and 90 percent in deaths of those who are infected. Ebola showed up without warning in the late 2000 in the northern district of Gulu in Uganda, Africa. Health care workers separated patients from others so they wouldn’t spread and get worse. There are 40 people that died in the first wave of the epidemic. The virus killed 224 people then out of nowhere it stopped and seems to have gone back into the jungle, this was in February 2001. There is a lot we still don’t know about the Ebola virus but the scientists began to piece of the things they don’t know together. The virus was discovered in the Democratic Republican of Congo in 1976. There are four different types of Ebola viruses. They are all named from where they are discovered at: Ebola – Zaire, Ebola – Sudan, Ebola – Ivory Coast, and Ebola – Reston. In 1989, the United States the Ebola – Reston virus was found in Reston, Virginia. There were sick monkeys imported from Philipines to a research lab. Some lab workers showed signs of the virus in the blood but didn’t become ill. Still don’t know where the virus is coming frombut think it resides in rain forests of Africa and Asia. The Ebola virus might as well be animal borne passed to primates like monkeys and apes and humans by another

To date there have been more cases and deaths during this outbreak of Ebola than all the other outbreaks together. The disease has spread between countries such as Guinea, Liberia and Sierra Leone due to very poor health systems, a lack of doctors and nurses as well as hospital and clinics, and because they have just recently come out of long periods of civil wars and instability. On August 8, 2014 the World Health Organization Director-General declared the West Africa outbreak a Public Health Emergency of International concern (World Health Organization,

G., & Schafer, I. J., (2014). Ebola Viral Disease Outbreak – West Africa, 2014. Morbidity and Mortality Weekly Report (MMWR), 63(25), 548-551. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6325a4.htm

The Ebola Haemorrahagic Fever, or Ebola for short, was first recognized as a virus in 1967. The first breakout that caused the Ebola virus to be recognized was in Zaire with 318 people infected and 280 killed. There are five subtypes of the Ebola virus, but only four of them affect humans. There are the Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast and the Ebola-Bundibugyo. The fifth one, the Ebola-Reston, only affects nonhuman primates. The Ebola-Zaire was recognized on August 26, 1976 with a 44 year old schoolteacher as the first reported case. The Ebola-Sudan virus was also recognized in 1976 and was thought to be that same as Ebola-Zaire and it is thought to have broken out in a cotton factory in the Sudan. The Ebola-Ivory Coast was

The Ebola virus is part of the filovirus family, and is known as Ebola hemorrhagic fever. The disease can sometimes cause hemorrhage from body openings, and the incubation period is 2 to 21 days. Humans are not infectious until they develop symptoms. The first few symptoms are sudden and include fever, fatigue, muscle pain, headache, and sore throat. These symptoms are then followed by vomiting, diarrhea, rash, and impaired kidney and liver function. Laboratory tests can include low white blood cell and platelet counts and elevated liver enzymes (World Health Organization [WHO], 2016a). Ebola can be spread from person to person transmission by direct contact with bodily fluids or contaminated objects. This mode of transmission puts people in regular contact with the infected body fluids at high risk of contracting Ebola (Cole, 2015). In particular, healthcare workers caring for infected patients are at risk for this infectious disease. The nurses, patient care technicians, and anyone working in the hospital is at risk for infection by simply doing their job. Calculating intake and output, checking vital signs, or simply assessing the patient can put these workers at risk. Healthcare workers question whether or not the new Ebola treatment protocols prevent them from becoming infected.