I have this task in organic chemistry (book: Brown's introduction to organic chemisty, global edition). Task 10:42. In (a) I have to tell what the funcion of K2CO3 is in step 1. Is it that CO32- take the hydrogen atom in 1-napthol? Will it then be a SN2 mechanism?In (b) I have to name the amine used in step 2 to form Propanolol. But I can't really find out how to come up with an amine that will make that reaction.Here are two pictures of the task: HIN2-DietnyiulShow how this compound can be prepared from ethylene(2)oxide and diethylamine.10.42 Following is a two-step synthesis of the antihyperten-sive drug propranolol, a so-called beta blocker with vasodilatingaction:-CH3OHK9CO3Cl+(1)1-NaphtholEpichlorohydrinis onef pro-hetics.chetics(2), andc acid(SeeN.(2)DHPropranolol(Cardinol)Propranolol and other beta blockers have received enormousclinical attention

Given reaction, Propranolol synthesis reaction.

HIN 2-Dietnyiul Show how this compound can be prepared from ethylene (2) oxide and diethylamine. 10.42 Following is a two-step synthesis of the antihyperten- sive drug propranolol, a so-called beta blocker with vasodilating action: -CH3 OH K9CO3 Cl + (1) 1-Naphthol Epichlorohydrin is one f pro- hetics. chetics (2) , and c acid (See N. (2) DH Propranolol (Cardinol) Propranolol and other beta blockers have received enormous clinical attention

HIN 2-Dietnyiul Show how this compound can be prepared from ethylene (2) oxide and diethylamine. 10.42 Following is a two-step synthesis of the antihyperten- sive drug propranolol, a so-called beta blocker with vasodilating action: -CH3 OH K9CO3 Cl + (1) 1-Naphthol Epichlorohydrin is one f pro- hetics. chetics (2) , and c acid (See N. (2) DH Propranolol (Cardinol) Propranolol and other beta blockers have received enormous clinical attention

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.38P: A step in a synthesis of PGE1 (prostaglandin E1, alprostadil) is the reaction of a trisubstituted...

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