Imatinib, a tyrosine kinase inhibitor, has revolutionized the treatment of chronic myelogenous leukemi (CML). Explain 1) why individuals with CML respond well to imatinib, 2) the mechanism of action of imatinib, and 3) the impact of imatinib on CML outcome/survival.

Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
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5. Imatinib, a tyrosine kinase inhibitor, has revolutionized the treatment of chronic myelogenous leukemia
(CML). Explain 1) why individuals with CML respond well to imatinib, 2) the mechanism of action of
imatinib, and 3) the impact of imatinib on CML outcome/survival.
Transcribed Image Text:5. Imatinib, a tyrosine kinase inhibitor, has revolutionized the treatment of chronic myelogenous leukemia (CML). Explain 1) why individuals with CML respond well to imatinib, 2) the mechanism of action of imatinib, and 3) the impact of imatinib on CML outcome/survival.
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