Propose an appropriate base to carry out the transformation below and use it as part of a curly arrow mechanism for the whole process. Meo ༠ OMe 1. base 2. ' ', Meo OMe
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- If the structure below is subjected to retrosynthetic analysis, which reagent is least useful?1.Explain why pyridine ( Kb=2.3x10-9) is a much stronger base than pyrrole (Kb=2.5x10-14), 2.Explain and illustrate, why it is difficult to perfom Friedel-Craft reactions on unactivated pyridine.Do a retrosynthetic analysis on the following compound, ending with the given starting material:
- Design a synthesis that would lead to the formation of the desired product. Please provide arrow pushing mechanism and provide reasoning for each step.Can someone help with the synthesis of this problem please?Show an actual arrow-pushing mechanism for the transformation below, and briefly explain the observed regioselectivity.
- Please perform a retrosynthesis for the image below including all the steps and reagentsMolecule 4 was prepared via molecule 3. Provide a complete curved arrow mechanism for the most straightforward conversion to 4. You can use HB+ as your acid and B: as your baseClassify following solvent as protic or aprotic CH3NO2
- Do a retrosynthetic analysis on the following compound, ending withavailable starting material.Perform a retrosynthetic analysis and suggest a synthesis of the target molecule (on the left) from the given starting material (on the right). (any reagents maybe usedShow how HC≡CH, CH3CH2Br, and (CH3)2CHCH2CH2Br can be used to prepare CH3CH2C≡CCH2CH2CH(CH3)2. Show all reagents, and use curved arrows to show movement of electron pairs.