Which of the following must be true based on the data below for ligand L binding to protein A and to protein B? Choice 1 of 4:Protein A binds at least 2 molecules of ligand L. Choice 2 of 4:The Kd for ligand binding to B is approximately 4 micromolar. Choice 3 of 4:When exposed to ligand L, protein A reaches maximal binding faster than does protein B. Choice 4 of 4:Protein B must adopt at least 2 different conformations with different binding affinities.
Which of the following must be true based on the data below for ligand L binding to protein A and to protein B? Choice 1 of 4:Protein A binds at least 2 molecules of ligand L. Choice 2 of 4:The Kd for ligand binding to B is approximately 4 micromolar. Choice 3 of 4:When exposed to ligand L, protein A reaches maximal binding faster than does protein B. Choice 4 of 4:Protein B must adopt at least 2 different conformations with different binding affinities.
Chapter15: Recirculating Systems
Section: Chapter Questions
Problem 3E
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Question
Which of the following must be true based on the data below for ligand L binding to protein A and to protein B?
Choice 1 of 4:Protein A binds at least 2 molecules of ligand L.
Choice 2 of 4:The Kd for ligand binding to B is approximately 4 micromolar.
Choice 3 of 4:When exposed to ligand L, protein A reaches maximal binding faster than does protein B.
Choice 4 of 4:Protein B must adopt at least 2 different conformations with different binding affinities.
Transcribed Image Text:1
0.9
0.8
0.7
0.6
0.5
-A
0.4
B
0.3
0.2
0.1
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Ligand Concentration (µM)
Fraction Bound
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