How we can use Dexamethasone in the context of COVID 19? What is the mechanism? As a pharmacist why you choose Dexamethasone? Please briefly answer at your own easy words. Please don't use AI for answering this question.
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How we can use Dexamethasone in the context of COVID 19? What is the mechanism? As a pharmacist why you choose Dexamethasone? Please briefly answer at your own easy words.
Please don't use AI for answering this question.
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- Drug absorption involves at least three distinct steps: dissolution, permeation, and disposition during transit in GI (an additional step of drug disposition in the body is involved as well for bioavailability). How are these processes validated in vitro when the in vivo requirement for drug bioavailability is waived?What is the mechanism(s) of action of the drug Riluzole in MND?A series of novel phenadoxone derivatives without mu2 receptor activity (mu2 activity is responsible for physical dependence) proposed to be developed as analgesics is shown below. Addition of which heterocyclic substituent R to phenadoxone is LIKELY to cause the MOST binding of the corresponding derivative to plasma proteins? Use the additivity of approximate estimates of logP to answer this question. phenadoxone derivatives A. Azetidine B. Thiophene C. Oxetane D. Furan E. Pyrrole ترف لي تي في R= -NH
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- What is Stem cell therapy for Covid-19? and What could be its possibilities and challenges?Give detailed Solution with explanation needed..don't use Ai for answering this..no need handwritten answer...Trelstar® is an injectable formulation of polylactide-co-glycolide (PLGA) microspheresencapsulating triptorelin palmoate (Mw 13115 Da), a synthetic decapeptide agonist analog ofgonadotropin releasing hormone (GnRH). The medicine is used in treatment of patients withprostate cancer. The pharmacokinetics of triptorelin palmoate as free drug follows a 3 compartmentmodel with drug half-lives estimated to be 6 minutes, 45 minutes, and 3 hours, respectively. Threedifferent dosing intervals of Trelstar® are available in clinic: 1 month (3.75 mg), 3 month (11.25mg) and 6 month (containing 22.5 mg of drug).Discuss how encapsulation into PLGA microspheres improves patient therapy with triptorelinpalmoate, and how three dosing intervals available in clinic may have been achieved bymodifications in the formulation