BIOS256 Lab Week 7

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Chamberlain University College of Nursing *

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256

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Biology

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Feb 20, 2024

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docx

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BIOS256 OL, Week 7 Lab Name: Paola Rodriguez OL Lab 7: Mendelian Inheritance: From genes to traits Learning Objectives : Explain how traits are passed on from parents to their offspring and the factors that causes variations. Apply Mendel’s Laws of Inheritance in color deficiency. Compare and predict the phenotypes of offspring with given genotypes using Punnett squares. Analyze dominant and recessive alleles, and how these alleles influence an individual’s biological make-up Our characteristics or traits are determined by our genes. In this simulation, you will learn how Mendelian postulates can be applied to determine the inheritance of characteristics. Also, you will reconnect to concepts in meiosis and gametogenesis and learn the laws of X linked inheritance to understand why color blindness affects more men than women. You will use mice as animal models to study how their genes can influence their fur color and apply these concepts to understand human color blindness. Using the Punnet squares and Pedigree trees, you will learn to predict the genetic makeup of a family and analyze if a color- blind individual can pass on the traits to the offsprings. Part 1: Complete Labster- Mendelian Inheritance: From genes to traits Part 2: Report and Reflection Purpose: Purpose: Describe in your own words and in complete sentences, the purpose of this experiment. The objective of this study is to investigate the transmission of genetic characteristics between parents and their progeny and the causes of variation. Observations: List 2 observations you have made in this simulation. When two brown mice were paired, brown offspring were born. Conversely, when a brown mouse was paired with a black mouse, three brown mice and one black mouse were born, as the brown fur allele was dominant over the black fur allele. Another observation is that the genetic basis for colorblindness is not as evenly distributed as the genetic basis for eye color.
BIOS256 OL, Week 7 Lab Name: Paola Rodriguez Answer all the questions below: 1. What is sex linked inheritance? Why are X linked genes more common in males than females. (2 points) Sex-linked inheritance refers to the genetic makeup of traits that are inherited from the sex chromosome genes. Females possess two sets of X-chromosomes, making X- linked traits more common in males. Males are affected by sex-linked diseases due to a mutation in the X chromosome. 2. What is X inactivation and what is the purpose of this process? (2 points) The process of inactivating the X chromosome is usually done on a cellular level during the early stages of development. Every female cell in the body has one working X- chromosome just like every male cell does. Because X is inactivated, there's only one working X chromosome in both male and female cells. 3. What is the difference between a heterozygous and a homozygous allele? Use an example to explain. (2 points) An individual with a heterozygous gene has two distinct alleles. For example, a person with one allele of the gene has brown eyes, while another allele has blue eyes. Conversely, a person with a homozygous gene has identical alleles, for example, both alleles of the gene have blue eyes. 4. From a recent blood typing, Jane discovered that her parents have type B blood, and she has type O. Is that possible? Explain using the Punnet square. (4 points) Jane blood type = O Jane’s parents blood type = B Jane’s parents are carriers of blood type O. B O B BB BO O BO OO 25% of the offspring of Jane’s parents including Jane will have O blood type.
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