BIOS256 Lab Week 7
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BIOS256 OL, Week 7 Lab
Name: Paola Rodriguez
OL Lab 7: Mendelian Inheritance: From genes to traits
Learning Objectives
:
Explain how traits are passed on from parents to their offspring and the factors that causes variations.
Apply Mendel’s Laws of Inheritance in color deficiency.
Compare and predict the phenotypes of offspring with given genotypes using Punnett squares.
Analyze dominant and recessive alleles, and how these alleles influence an individual’s biological make-up
Our characteristics or traits are determined by our genes. In this simulation, you will learn how Mendelian postulates can be applied to determine the inheritance of characteristics. Also, you will reconnect to concepts in meiosis and gametogenesis and learn the laws of X linked inheritance to understand why color blindness affects more men than women.
You will use mice as animal models to study how their genes can influence their fur color and apply these concepts to understand human color blindness. Using the Punnet squares and Pedigree trees, you will learn to predict the genetic makeup of a family and analyze if a color-
blind individual can pass on the traits to the offsprings.
Part 1: Complete Labster- Mendelian Inheritance: From genes to traits
Part 2: Report and Reflection
Purpose:
Purpose: Describe in your own words and in complete sentences, the purpose of this experiment. The objective of this study is to investigate the transmission of genetic characteristics between parents and their progeny and the causes of variation.
Observations: List 2 observations you have made in this simulation.
When two brown mice were paired, brown offspring were born. Conversely, when a brown mouse was paired with a black mouse, three brown mice and one black mouse were born, as the brown fur allele was dominant over the black fur allele. Another observation is that the genetic basis for colorblindness is not as evenly distributed as the genetic basis for eye color.
BIOS256 OL, Week 7 Lab
Name: Paola Rodriguez
Answer all the questions below:
1. What is sex linked inheritance? Why are X linked genes more common in males than females. (2 points)
Sex-linked inheritance refers to the genetic makeup of traits that are inherited from the sex chromosome genes. Females possess two sets of X-chromosomes, making X-
linked traits more common in males. Males are affected by sex-linked diseases due to a
mutation in the X chromosome.
2. What is X inactivation and what is the purpose of this process? (2 points)
The process of inactivating the X chromosome is usually done on a cellular level during the early stages of development. Every female cell in the body has one working X-
chromosome just like every male cell does. Because X is inactivated, there's only one working X chromosome in both male and female cells.
3. What is the difference between a heterozygous and a homozygous allele? Use an example to explain. (2 points)
An individual with a heterozygous gene has two distinct alleles. For example, a person with one allele of the gene has brown eyes, while another allele has blue eyes. Conversely, a person with a homozygous gene has identical alleles, for example, both alleles of the gene have blue eyes.
4. From a recent blood typing, Jane discovered that her parents have type B blood, and she has type O. Is that possible? Explain using the Punnet square. (4 points)
Jane blood type = O Jane’s parents blood type = B Jane’s parents are carriers of blood type O.
B
O
B
BB
BO
O
BO
OO
25% of the offspring of Jane’s parents including Jane will have O blood type.
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Related Questions
Please help asap
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Pls help ASAP. Do both parts a and b
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Learning Task # 2. Punnett Square
a. Given the cross AaBb X AaBb, construct a Punnett square and determine the genotypic ratio (the probability that a particular
genotype will occur) of the resulting cross
b. Given this cross, TtGg X TtGg, fill-up the squares with the correct answer.
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Please help me with this one.
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ARTER 1
WEEK 5- WEEK 6
WRITTEN WORKS (30% OF YOUR GPAD
ANSWER THE EOU
E
Learning Task 5: Read and understand the pattern of inheritance in multiple
alleles. Answer the guide question in your
notebook.
Multiple Alleles
Mendel studied just two alleles of his pea genes, but real populations of-
ten have multiple alleles of a given gene, In this activity you will learn how to
crossed the gene for coat color in rabbits (the C gene) which comes in four color
alleles (C, Cch, Ch,
c) as shown by the figure
De
below.
Pe e
ALBNO
ACH
CHINTHLLA
HAILAYN
Using the given genotypes, find the Fl and F2 generation of the crossed between
black rabbit and chinchilla, the crossed of himalayan and albino. Use the Punnet
squares below to guide you.
A. Black (CC) x Chinchilla (CchCch)
F1 Offspring with corresponding %
Fa Offspring with corresponding %
Guide Question
1. Based on the results of the genetic crosses you have shown, how do you
think the red and white flower alleles can "interact with one another?…
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SUBJECT: GENETICS
Topic: Polygenic Inheritance
Question: Discuss possible presentation why a given family with 12 children, has 7 variations/differences in terms of height (contributing alleles like AABBCCDDEEFF, non-contributing alleles, aabbccddeeff)
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Performance Task: Regular Biology
Name:
Who Gets the Money? Worksheet
O bindgdoaolon0ne
Part Two: Co-dominance and Incomplete dominance
Now that
have been eliminated, lawyers order blood tests to try to
prove their claims. The lawyers have also done some research and read that hair texture is
inherited.
Type A and type B blood are co-dominant over type O.
Rh+ blood is dominant over Rh- blood.
Hair texture exhibits incomplete dominance. Homozygous dominants (HH) have curly hair.
Homozygous recessives (hh) hawe straight hair. Heterozygotes (Hh) have wavy hair.
Homozygous type A blood, heterozygous Rh+, straight hair.
Heterozygous type B blood, homozygous Rh+, wavy hai
Heterozygous type A blood, heterozygous Rh+, wavy hair.
Heterozygous type A blood, homozygous Rh+, wavy hair.
Type O blood, Rh-, straight hair.
Mr. Jones
Mrs. Jones
Carl
Dale
Earl
In the space below, draw three Punnett Squares showing the possible offspring of Mr. and Mrs.
Jones: for blood type, Rh type, and hair textures.…
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Activity 1B: Identical or Non-identical?
Direction: Complete the table below by classifying the genotypes in Column
1 as homozygous dominant, heterozygous, or homozygous recessive basing
on the allele combination given. Write your answers in column 2. An example
is given for your guidance.
GENOTYPE
1. HH
2. Rr
CLASSIFICATION
Homozygous dominant
3. aa
4. Dd
5. TT
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ull T-Mobile LTE
10:32 PM
© 73%
Mendelian Genetics Lab LASC...
MENDELIAN GENETICS
Define the following terms:
Gene:
Homozygous:
Allele:
Heterozygous:
Phenotype:
Dominant:
Genotype:
Recessive:
P, F1, F2 generations:
Introduction to probability
To understand genetics, it is essential to understand probability.
The numerical value of the probability of an event can range
from 0 (impossible) to 1 (certainty). For example, what is the
probability of flipping a coin and getting tails? There are two
possible outcomes (heads and tails) that are equally likely, but
we are looking for the probability of just one of them (tails).
Probability of tails = ½ = 0.5.
What is the probability of tossing a six-sided die and getting a
four?
What is the probability of tossing a six-sided die and getting an
even number?
What is the probability of tossing a six-sided die and NOT
getting a four?
The first law of probability states that the results of one trial do
NOT influence the results of later trials for…
arrow_forward
Station 4: Pedigrees inidoned : no
Pattern of inheritance (monohybrid, dihybrid, sex-linked, and genetically linked genes) can often be
predicted from data, including pedigree, that give the parent genotype/phenotype and the offspring
genotypes/phenotypes.
III
I
II
1. Identify the type of inheritance in each of the following pedigrees(autosomal dominant, autosomal
recessive, sex linked) AND EXPLAIN why it is that type of inheritance
20
2
21
O
O
2. The pedigree below shows a family with a history of a recessive disease. DETERMINE the genotype
of each individual for an autosomal trait
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C. Give the genotypic and phenotypic ratios 1. Hemophilia is a disease caused by a gene found on the X chromosome. The recessive allele causes the disease. Tall (T) is dominant over short (t). A homozygous tall female carrier marries a short hemophiliac male. Predict the genotype and phenotype of their offspring.
2. In mice, the ability to run normally is a dominant trait. Mice with this trait are called running mice (R). The recessive trait causes mice to run in circles only. Mice with this trait are called waltzing mice (r). Hair color is also inherited in mice. Black hair (B) is dominant over brown hair (b). 2 heterozygous running, heterozygous black mice were crossed. Give the genotypic and phenotypic ratios of their offspring.
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Lab Exercises: In these exercises, you will learn to use the Punnett square to determine geno-
typic and phenotypic outcomes for monohybrid, dihybrid, incomplete, codominant, epistatic,
and sex-linked traits.
Exercise #1: Monohybrid Crosses
A male with blue eyes has a child with a homozygous dominant brown-eyed female. What
are the genotypes and phenotypes of the resulting offspring?
1.
Genotype rahio
R RR
Rr
Phenoty pe vatio
Rr
Y
FEx PT
A male offspring from above has four children with his heterozygous brown-eyed wife.
What are the genotypes and phenotypes of the resulting offspring? What are the genotypic
Rt
2.
and phenotypic ratios?
Y
RR IRr
K
r Rr
Yr
3. A heterozygous brown-eyed male has four children with his blue-eyed wife. What are the
genotypes and phenotypes of the resulting offspring? What are the genotypic and pheno-
typic ratios?
120
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Unit 7: Genetics
Objectives
A. Distinguish between the dominant and recessive traits.
B. State two laws of heredity that were developed from Mendel's work. Be sure
you can explain them.
C. Explain the difference between a gene and an allele.
D. Describe how Mendel's results can be explained by scientific knowledge of
genes.
E. Use a Punnett square to predict the results of monohybrid and dihybrid
crosses.
F. Differentiate between a monohybrid and dihybrid cross.
G. Be able to complete and interpret
- monohybrid crosses
- dihybrid crosses
- crosses with co-dominant alleles
H. Explain the role of sex chromosomes is sex determination.
1. Explain the effect of crossing over on the inheritance of genes in linkage groups
e lo read, make, an analyze a pedigree
3 List And des cribɛ ine poducts of meiosis
K CompArEthe produts of mitosis And tho se ofmeiosi's
Practice Questions
1. When Mendel crossed a strain of tall pea plants with a strain of short pea
plants, he observed that all of the…
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Learning task 17-01: Your Phenotype and Genotype
Select 10 different traits that are of interest to you. For each trait, identify your own phenotype
and your possible genotype(s).
Trait 1:
Phenotype:
Genotype:
Trait 2:
Phenotype:
Genotype:
Trait 3:
Phenotype:
Genotype:
Trait 4:
Phenotype:
Genotype:
Trait 5:
Phenotype:
Genotype:
Trait 6:
Phenotype:
Genotype:
Trait 7:
Phenotype:
Genotype:
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PLEASE ANSWER NUMBER 2. THANKYOU!
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Questions: Show your work using Punnett Squares.
1. Cross these two parents: AA x BO. What are the genotypes and phenotypes of the children?
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asap pleass
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SUBJECT: GENETICS
Topic: Probability
1. Consider albinism a trait to occur in a human family. If two parents areheterozygous for such trait, the probability of having a normally pigmented child is 3//4 and having an albino child is ¼. What is the probability that 2 will be normal and 1 will be albino?
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NAME:
Patterns of Inheritance Worksheet
1. True Breeding Parental Cross
A homozygous dominant purple flowered plant is crossed with a
homozygous recessive white flowered plant.
a. What are the genotypes of the parent plants?
(Use the Punnett square to determine the outcomes of this cross.
Remember to place the gametes along the left side and top of the square.
(P=Purple, p=white)
b. What is the genotype of all F₁ plants?
1
b.
c. What is the phenotype of all F₁ plants?
C.
d. How many plants out of 4 will produce white flowers?
d.
a.
2. Monohybrid Cross:
The F₁ offspring from the above problem are allowed to self fertilize.
a. What are the genotypes of the F₁ parents?
a.
(Use the Punnett square to determine the outcomes of this cross.
Remember to place the gametes along the left side and top of the
square.)
b. What is the genotype ratio for this cross?
c. What is the phenotype ratio for this cross?
d. How many plants out of 4 will produces white flowers?
d.
b.
C.
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13:10
l 5G
Done
Photo
Use the following information to answer question 3.
In sheep, white wool is a dominant trait and black wool is a recessive trait. In a herd
of 500 sheep, 20 sheep have black wool.
Numerical Response:
Bb
20
3. In this herd, what is the frequency of the heterozygous genotype?
Answer:
Record your answer as a value from 0 to 1, rounded to two decimal places.
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Help!?
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Monohybrid Cross Worksheet
Directions: Answer each of the following questions using a Punnett Square and the rules of monohybrid crosses.
The allele for dimples (D) is dominant to the allele for no dimples (d). A man heterozygous for dimples marries a woman who is also heterozygous for dimples.
What is the man’s genotype and the woman’s genotype?
What is the man’s phenotype and the woman’s phenotype?
Do a cross to determine all potential dimple genotypes and phenotypes for the offspring of this man and woman.
The allele for hitchhiker’s thumb (h) is recessive to straight thumb (H). If a man and his wife are both homozygous recessive, will any of their offspring potentially have hitchhikers thumb?
What is the man’s genotype and the woman’s genotype?
What is the man’s phenotype and the woman’s phenotype?
What genotype(s) must the offspring have in order to have the phenotypic trait of hitchhiker’s thumb?
Do a cross to determine all potential hitchhiker’s…
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Activity: Who's the Real Father?
Nathaniel lost his mom Rachel. According to the family
lawyer, all of his mom's properties will be given to him and a
part of it to his father. But he never met his father because
according to his mom, they gat separated due to marital
issues, On the burial, three men came and claimed that one of
them is his father. Nathaniel knew that his blood type is O (ii)
while his mom's is B (Bi). Who could be his father among
three men if their blood type is as follows?
the
• Father 1: Paul James
Occupation: Businessman
Blood Type: AB
Father 2: Paul John
Occupation: Professional Singer
Blood Type: B
Father 3: Paul Jeric
Ocupation: Policeman
Blood Type: A
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Question:
The disorder: Red-Green color blindness
Explain the mode of inheritance of the disorder (recessive, dominant, x-linked, etc.)
. Can a person be a carrier of this disorder?
• Describe the probability of having a child with the disorder -- give a specific scenario (ex. both parents are heterozygous for
the trait)
• Describe the symptoms associated with this disorder
Explain the prognosis of a person born with this disorder
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Please answer ALL parts.
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Activity #6: Extension of Mendelian Problem
1. Smith and Mrs. Doe were roommates at Harris Hospital and both had daughters at about
the same time. After Mrs. Smith took Susie home, she became convinced that the babies had
been switched. Blood tests were performed with the following results: Mr. and Mrs. Smith
were both type AB; Mr. and Mrs. Doe were both type A; Susie Smith was type A and Debbie
Doe was type 0.
Had a switch occurred?
2. In guinea pigs, coat color is governed by four alleles that constitute a multiple allelic
series, C (black), cS (sepia), cC (cream), and c (albino) with the following dominance
hierarchy: C>cS>cC>c. Determine the phenotypic ratios of the progeny from the following
crosses:
а. Сс х Сcs
b. CcS x cCc
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Please complete answers than rating helpful other wise un helpful please complete
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Name:
Date: 11 9J1 Block 1
Benchmark Quarter 3 Study guide
Trait: Neurofibromatosis
Forms of the trait:
A The dominant form is neurofibmmatosis, caused by the production of an abnormal form of the protein
neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous
tumors that can interfere with the nervous system and cause blindness Some tumors can convert to a
cancerous form
A The recessive form is a pormal protein-in other words, no neurofibromatosis
A typical pedigree for a famity that caries neurofibromatosis is shown below Note that carriers are not
indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis
allele, and the letter "n" for the normal allele.
Nn
nn
3
nn
1. Is this autosomal or sex-linked? Why?
2. Is individual #1 most likely homozygous dominant or heterozygous? Explain how you
can tell
3. What is the genotype of individual # 3?
4. Can you be sure of the genotype of the affected…
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Topic: Modifications of Mendelian Genetics
LEARNING ACTIVITY and ASSESSMENT
1. In addition to the ABO blood group, many others have been identified in humans. One such
group is the MN group, controlled by two codominant alleles, M and N, at one locus. What will
be the probability of the genotypes and phenotypes that would be produced in crosses
involving the following phenotypes:
а. Туре М and type N
b. Туре М and type MN
c. Type N and type N
d. Type MN and type MN
2. Could a child of type N result from the mating of M and MN? Justify your answer.
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- Please help asaparrow_forwardPls help ASAP. Do both parts a and barrow_forwardLearning Task # 2. Punnett Square a. Given the cross AaBb X AaBb, construct a Punnett square and determine the genotypic ratio (the probability that a particular genotype will occur) of the resulting cross b. Given this cross, TtGg X TtGg, fill-up the squares with the correct answer.arrow_forward
- Please help me with this one.arrow_forwardARTER 1 WEEK 5- WEEK 6 WRITTEN WORKS (30% OF YOUR GPAD ANSWER THE EOU E Learning Task 5: Read and understand the pattern of inheritance in multiple alleles. Answer the guide question in your notebook. Multiple Alleles Mendel studied just two alleles of his pea genes, but real populations of- ten have multiple alleles of a given gene, In this activity you will learn how to crossed the gene for coat color in rabbits (the C gene) which comes in four color alleles (C, Cch, Ch, c) as shown by the figure De below. Pe e ALBNO ACH CHINTHLLA HAILAYN Using the given genotypes, find the Fl and F2 generation of the crossed between black rabbit and chinchilla, the crossed of himalayan and albino. Use the Punnet squares below to guide you. A. Black (CC) x Chinchilla (CchCch) F1 Offspring with corresponding % Fa Offspring with corresponding % Guide Question 1. Based on the results of the genetic crosses you have shown, how do you think the red and white flower alleles can "interact with one another?…arrow_forwardSUBJECT: GENETICS Topic: Polygenic Inheritance Question: Discuss possible presentation why a given family with 12 children, has 7 variations/differences in terms of height (contributing alleles like AABBCCDDEEFF, non-contributing alleles, aabbccddeeff)arrow_forward
- Performance Task: Regular Biology Name: Who Gets the Money? Worksheet O bindgdoaolon0ne Part Two: Co-dominance and Incomplete dominance Now that have been eliminated, lawyers order blood tests to try to prove their claims. The lawyers have also done some research and read that hair texture is inherited. Type A and type B blood are co-dominant over type O. Rh+ blood is dominant over Rh- blood. Hair texture exhibits incomplete dominance. Homozygous dominants (HH) have curly hair. Homozygous recessives (hh) hawe straight hair. Heterozygotes (Hh) have wavy hair. Homozygous type A blood, heterozygous Rh+, straight hair. Heterozygous type B blood, homozygous Rh+, wavy hai Heterozygous type A blood, heterozygous Rh+, wavy hair. Heterozygous type A blood, homozygous Rh+, wavy hair. Type O blood, Rh-, straight hair. Mr. Jones Mrs. Jones Carl Dale Earl In the space below, draw three Punnett Squares showing the possible offspring of Mr. and Mrs. Jones: for blood type, Rh type, and hair textures.…arrow_forwardActivity 1B: Identical or Non-identical? Direction: Complete the table below by classifying the genotypes in Column 1 as homozygous dominant, heterozygous, or homozygous recessive basing on the allele combination given. Write your answers in column 2. An example is given for your guidance. GENOTYPE 1. HH 2. Rr CLASSIFICATION Homozygous dominant 3. aa 4. Dd 5. TTarrow_forwardull T-Mobile LTE 10:32 PM © 73% Mendelian Genetics Lab LASC... MENDELIAN GENETICS Define the following terms: Gene: Homozygous: Allele: Heterozygous: Phenotype: Dominant: Genotype: Recessive: P, F1, F2 generations: Introduction to probability To understand genetics, it is essential to understand probability. The numerical value of the probability of an event can range from 0 (impossible) to 1 (certainty). For example, what is the probability of flipping a coin and getting tails? There are two possible outcomes (heads and tails) that are equally likely, but we are looking for the probability of just one of them (tails). Probability of tails = ½ = 0.5. What is the probability of tossing a six-sided die and getting a four? What is the probability of tossing a six-sided die and getting an even number? What is the probability of tossing a six-sided die and NOT getting a four? The first law of probability states that the results of one trial do NOT influence the results of later trials for…arrow_forward
- Station 4: Pedigrees inidoned : no Pattern of inheritance (monohybrid, dihybrid, sex-linked, and genetically linked genes) can often be predicted from data, including pedigree, that give the parent genotype/phenotype and the offspring genotypes/phenotypes. III I II 1. Identify the type of inheritance in each of the following pedigrees(autosomal dominant, autosomal recessive, sex linked) AND EXPLAIN why it is that type of inheritance 20 2 21 O O 2. The pedigree below shows a family with a history of a recessive disease. DETERMINE the genotype of each individual for an autosomal traitarrow_forwardC. Give the genotypic and phenotypic ratios 1. Hemophilia is a disease caused by a gene found on the X chromosome. The recessive allele causes the disease. Tall (T) is dominant over short (t). A homozygous tall female carrier marries a short hemophiliac male. Predict the genotype and phenotype of their offspring. 2. In mice, the ability to run normally is a dominant trait. Mice with this trait are called running mice (R). The recessive trait causes mice to run in circles only. Mice with this trait are called waltzing mice (r). Hair color is also inherited in mice. Black hair (B) is dominant over brown hair (b). 2 heterozygous running, heterozygous black mice were crossed. Give the genotypic and phenotypic ratios of their offspring.arrow_forwardLab Exercises: In these exercises, you will learn to use the Punnett square to determine geno- typic and phenotypic outcomes for monohybrid, dihybrid, incomplete, codominant, epistatic, and sex-linked traits. Exercise #1: Monohybrid Crosses A male with blue eyes has a child with a homozygous dominant brown-eyed female. What are the genotypes and phenotypes of the resulting offspring? 1. Genotype rahio R RR Rr Phenoty pe vatio Rr Y FEx PT A male offspring from above has four children with his heterozygous brown-eyed wife. What are the genotypes and phenotypes of the resulting offspring? What are the genotypic Rt 2. and phenotypic ratios? Y RR IRr K r Rr Yr 3. A heterozygous brown-eyed male has four children with his blue-eyed wife. What are the genotypes and phenotypes of the resulting offspring? What are the genotypic and pheno- typic ratios? 120arrow_forward
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