SexLinkedGenesRecombinationsOctober30th

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University of Cincinnati, Main Campus *

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1081

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Biology

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Dec 6, 2023

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pdf

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6

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Test Crosses What is a test cross? What are they used for? You perform a test cross on some hamsters. You want to know if your brown hamster carries the allele for albinism, a recessive mutation which causes no pigment production. When you breed your hamster with an albino hamster (bb), you get the following results: 4 brown hamsters and 4 albino hamsters. Does your hamster carry the albino allele? Show your work. Sexual Inheritance What do the sex chromosomes look like for males and females in these animal species? Female Male Humans/Drosophila Birds Grasshoppers Honeybees What is the SRY gene? What chromosome is it found on?
What is X inactivation in females? Why do we do X inactivation? Is the inactivated chromosome destroyed? What are Barr bodies? Draw x-inactivation in Calico cats (orange fur, black fur, and white fur). What sex are calico cats usually? Why? Why is mitochondrial DNA inherited from only the mother? If a mother with a mitochondrial disease has children, what percent of her children will have the disease? What about if a father has mitochondrial disease? What is the difference between mitochondrial diseases and Sex-linked diseases? What are epigenetics? What is genetic imprinting? What mechanism does imprinting use?
Sex-linked traits practice problems Judy is a carrier of colorblindness. Her husband Jude has normal vision. Judy is 12 weeks pregnant! What is the probability that their child will be colorblind? Hint… if Judy is a carrier, is colorblindness dominant or recessive? In fruit flies, eye color is a sex-linked trait. Red is dominant to white. Show the cross of a white eyed female, red-eyed male. What is the probability that they will produce a red-eyed offspring? Recombination What are linked genes? Why are they usually inherited together? Determine the recombination frequency for the mating of a homozygous dominant fruit fly (red eyes, long wings) and a homozygous recessive fruit fly (purple eyes, vestigial wings), given these frequencies: Red eyes, long wings: 1339 Purple eyes, vestigial wings: 1195 Red eyes, vestigial wings: 151 Purple eyes, long wings: 154
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