W10 worksheet - Copy - Copy (1)

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Dec 6, 2023

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W10 Worksheet: Urinalysis Follow the instructions below very carefully. Many of the items in this assignment require reading, or videos, or something else to do. Each question has either a text box that can be filled out or a box that can be checked to show completion. Be sure to type out your answers completely and expand the text boxes if you need the additional space. Question 1 --- 2 points Urinalysis Some urinary system diseases can have relatively insignificant symptoms in the early stages. The careful analysis of urine and urine production can sometimes reveal pathology that would normally go unnoticed for a long time. Just a few examples of such diseases that urinalysis might help identify are diabetes, various forms of urinary tract infections, and kidney disease. If you are attending the lab, your lab instructor will give you a urinalysis reagent strip and let you do your own analysis. Go to the urinalysis presentation (links to an external site) to do a tutorial that will guide you through some practice with urinalysis, then answer the following questions. Please remember that links in this worksheet generally open up a new window, so you may need to close it to return to this worksheet. Which of the following results from a urinalysis reagent strip would most likely suggest that there is an increase of red blood cell break down in the body? Choose one: High levels of urobilinogen in the urine Low levels of glucose in the urine Blood in the urine High levels of ketones in the urine Question 2 --- 2 points Which of the following results from a urinalysis reagent strip would most likely suggest that someone was following an extreme and long-term version of the Atkins diet? Choose one: Increased urobilinogen in the urine Increased ketones in the urine Increased glucose in the urine Increased protein in the urine
Question 3 --- 2 points Some patients who take a class of drugs called statins can experience a side effect called rhabdomyolysis. Which of the following results from a urinalysis reagent strip would most likely suggest that a person was experiencing this negative side effect? Choose one: Increased glucose in the urine Increased ketones in the urine Increased protein in the urine Increased leukocytes in the urine Question 4 --- 2 points Do your own research on the internet and explain what rhabdomyolysis is. Make sure you include some of the causes of this condition. Your answer: Rhabdomyolysis is a medical condition. It involves the breakdown of muscle tissue, releasing some things from the inside of the muscle that can harm us. These released contents include myoglobin, creatine kinase, and other proteins, which can be harmful to the kidneys and other organs. Causes that could lead to rhabdomyolysis include physical trauma, extreme physical activity, infections, and heat stroke. Question 5 --- 2 points Glomerular Filtration Rate and Renal Clearance This section of the lab discusses the fraction of plasma that actually gets filtered by the kidneys as it passes through the kidneys. The kidneys have the responsibility to filter our blood and remove toxins and waste products. Kidneys also regulate fluid removal from our blood and body. This helps us control our blood pressure. Kidneys also help regulate the concentration of many important ions and nutrients. Finally, kidneys help us regulate our pH within a very narrow acceptable range. For all these reasons, it is important for us to measure how well the kidneys are functioning when we track a person’s health. Watch “ GFR Inulin ” (8:42 mins; Transcript; links to an external site) which discusses the concepts of filtration, reabsorption, secretion, and excretion. This video will also discuss the concept of glomerular filtration rate (GFR) and the role of inulin in calculating GFR.
View the Plasma Clearance presentation (links to an external site) to complete a short tutorial on creatinine clearance. Use the knowledge you gained from the assignments above to answer the following questions. Substance Clearance (Cx) Inulin Cx = 125 ml/min Glucose Cx = 0 ml/min PAH Cx = 625 ml/min Urea Cx = 70 ml/min Cl- Cx = 8 ml/min Creatinine Cx = 120 ml/min Look at the information above, and decide which substance appears to be extensively secreted. Choose one: Inulin Glucose PAH Urea CI- Creatinine Question 6 --- 2 points Substance Clearance (Cx) Inulin Cx = 125 ml/min Glucose Cx = 0 ml/min PAH Cx = 625 ml/min Urea Cx = 70 ml/min Cl- Cx = 8 ml/min Creatinine Cx = 120 ml/min Look again at the information above, and decide which substance appears to be extensively reabsorbed. 1. Inulin and creatinine 2. PAH 3. Urea and creatinine 4. Glucose and Cl-
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