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Temple University *

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Biology

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Dec 6, 2023

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Antawn James Student at temple university The bionic human Cezary Marcinkiewicz BACKGROUND Artificial organs are synthetic replacements for natural organs, designed to mimic both their form and function. These bioengineered organs can be custom-tailored to meet specific patient needs, mitigating many limitations associated with traditional organ transplantation. Unlike donor organs, artificial organs can be manufactured on demand, dramatically reducing the waiting time for life-saving treatments and the risks of organ rejection. As a result, artificial organs hold great potential in offering new hope to individuals who would otherwise remain on transplant waiting lists. PROPOSAL The increasing prevalence of organ failure underscores the urgency for research, development, and implementation of artificial organs. These technologies have the potential to save lives and significantly improve the quality of life for those in need. The key advantages of artificial organs include their potential for customization, scalability, and reduced dependency on donor organs. This essay aims to explore how artificial organs can help overcome the limitations of traditional organ transplantation and provide a more efficient and accessible solution to the increasing demand for life-saving treatments. So with that being said I would like to write a paper that goes over the Examination of the current state of artificial organ research and development, focusing on replicating the functionality, vascularization, and biocompatibility of natural organs. While also going over the trials and longevity of the organ itself. I would also like to look into the regulatory challenges and processes involved in bringing artificial organs to the market and ensuring compliance with safety and quality standards. I would also like to Explore real-world case studies and examples of artificial organ development and implementation to illustrate their impact on patients' lives as well as Discuss strategies to make artificial organs accessible and affordable to a wider range of patients, regardless of their socio-economic status. There are also policies that need to be followed in order to give these organs out so I will Examine the ethical and policy implications surrounding artificial organs, including regulatory approval, patient access, and affordability. The advancement of artificial organs is a transformative endeavor with the potential to significantly enhance the quality of life for countless individuals suffering from organ failure. I could also I nterview experts in the field of regenerative medicine and artificial organ development to gain insights into the current state of research and potential future directions . By addressing the objectives outlined in this proposal, we can shed light on the current state of artificial organ development, the challenges and opportunities they present, and the potential benefits they offer. Ultimately, this essay aims to contribute to the ongoing dialogue surrounding artificial organs and their promise to reshape the landscape of healthcare, offering new hope to those in need of organ transplantation. Through this essay, we hope to highlight the significance of advancing artificial organs and the potential they hold for improving the quality of life for millions of individuals globally, while also fostering discussions on policy, ethics, and accessibility in the field of regenerative medicine.
REFERENCES: Allied alliance of advanced biomedical engineering https://aabme.asme.org/posts/innovations-in-artificial-organs#:~:text=The%20first%20real %20breakthrough%20in,the%20design%20of%20Jarvik%2D7 . Artificial organs: innovating to replace donors and dialysis https://www.the-scientist.com/sponsored-article/artificial-organs-innovating-to-replace-donors-and- dialysis-70907 Clark K Colton, “implantable biohybrid artificial organs” Cell transplantation volume 4 issue 4 Page 415-436 https://www.sciencedirect.com/science/article/abs/pii/096368979500025S https://www.liebertpub.com/doi/abs/10.1089/end.2000.14.49 ANTHONY ATALA 16 Mar 2009 https://doi.org/10.1089/end.2000.14.49 Medical applications of membranes: Drug delivery, artificial organs and tissue engineering Dimitrios F. Stamatialis a , Bernke J. Papenburg a , Miriam Gironés a , Saiful Saiful a , Srivatsa N.M. Bettahalli a , Stephanie Schmitmeier b , Matthias Wessling a https://doi.org/10.1016/j.memsci.2007.09.059 Tissue Bioengineering and Artificial Organs Sara Llames , Eva García , Jesús Otero Hernández & Álvaro Meana
https://link.springer.com/chapter/10.1007/978-1-4614-2098-9_20
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