Drugs and Behavior Practice Exam Two

9. If the concentration of a plasma carrier was diminished, what would this do to the half-life of a steroid? a. increase half-life   b. decrease half-life   c. no change   d. it depends on the steroid 10. Put the steps involved in generation and release of peptide hormones in the correct order:   1)cleavage into active hormone 2) transport into blood capillary 3)mRNA translation and preprohormone entrance into the ER 4) release signal into ECF 5)vesicular transport into Golgi apparatus   6)signal sequence peptide cleavage into prohormone

1. Jesse age 27 complaints of muscle spasm, sweating abdominal pain and diarrhea. You know that her temperature is 101, pulse is 120 and her BP is 186/92. In reviewing her medications you note but she is taking fluoxetine (Prozac) and Sertraline (Zoloft), which life threatening events may she be experiencing? a. Neuroleptic malignant syndrome b. Monamine oxidase crisis c. Serotonin syndrome d. Hyperpyrexia

Which of the following are true statements? [Select all that apply.] 1. Opioid drugs are much safer than most prescription drugs. 2. There is strong evidence to support the use of opioids for chronic noncancer pain. 3. Abuse of opioid drugs presents a serious public health problem. 4. The financial success of OxyContin is in large part due to aggressive marketing by its manufacturer.

1).The process by which messages are communicated within the cell is A. Proliferation B.DN transcription C. signal transduction D. migration.       2.) Which of the following medications is a dopamine antagonist? A. Haloperidol B. Granisetron C. Olanzapine D. Dronabinol.                                             3) what testing should the nurse expect the patient to have prior to beginning treatment with bleomycin? A. Pulmonary function test B. Echocardiogram, C.Lumbar puncture D. Bone marrow biopsy.           Please do not plarized & give answer with explanation

21. Which adjunctive therapy will not increase dopamine levels in the brain when given together with levodopa? a. Entacapone b. Benserazide c. Carbidopa d. Procyclidine e. Rasagiline

18.  Studies have shown that oxytocin acts as an "anti-social" hormone in humans, promoting aggression and avoidance. a. True b. False

1 and 2 questions pls 1.) The sympathetic nervous system secretes epinephrine at its axon terminals in the internal organs and the adrenal medulla secretes it into the bloodstream . Which of the following statements which compare the two sources of epinephrine is (are ) correct ? 1. Epinephrine from the sympathetic system is released faster . 2. Epinephrine from the sympathetic system is released more slowly 3. The effects of epinephrine from the adrenal medulla last longer . 4. The effects of epinephrine from the adrenal medulla disappear more quickly a.) 3 only B.) 1 only C.) 1 and 3 D.) 2 and 4 2.) The nervous system and the endocrine system are very closely related in the way they maintain homeostasis One of the important shared characteristics is that they both A.)send information through the body via action potentials B.) send information through the body via the blood stream C.) function independently of conditions in the external environment D.) produce chemicals…

Restless leg Syndrome is ? 1. Linked to genetics: Researchers do not know the cause of restless legs syndrome however, they suspect that genes play a role. Nearly half of people with RLS also have a family member with the condition.2. Because RLS seems to be caused by a dopamine shortage in the brain, drugs that stimulate the cells to produce Dopamine are a form of therapy.3. Restless legs syndrome (RLS) is a disorder of the part of the nervous system that causes an urge to move the legs. Because it usually interferes with sleep, it also is considered a sleep disorder.4. All the above

8. Cushing’s syndrome results from A. hypersecretions of hormones from the adrenal cortex. B. hypersecretions of hormones from the parathyroid gland. C. hyperfunctioning of hormones from the pituitary gland. ____ 9. Meningitis is an inflammation of the linings of the brain and spinal cord and is always caused by bacteria. A. True B. False 50. Coronary artery disease is the narrowing of arteries that supply oxygen and nutrient-filled blood to the heart. A. True B. False

37. Which is not TRUE in the following statements? * a. Hormones affect various processes in the body as they regulate and balance the functioning of organs, tissues, and cells. b. Hormones greatly influence growth, appearance, emotions, and reproductive functions. c. Hormones play an essential role in the occurrence of disorders such as diabetes, thyroid disease, growth and/or sexual dysfunction. O d. Too much secretion of hormones does not affect homeostasis. 39. Which of the following statements best explains the Theory of Natural Selection? * a. Organs that are not used may disappear while organs that are constantly used may develop. b. In nature, the organisms with desirable characteristics may survive while those with weaker traits may not. O c. Organisms develop desirable structures to survive in a given environment. d. Acquired characteristics of parents can be passed on to offsprings. оо O O

1. What is the medical science concerned with the use of drugs in the treatment of disease? * a Pharmacotherapeutics b Pharmacology c Pharmacoepidemiology Pharmacognosy d Pharmacogenetics 2 Which of the following is ACCURATE about Reboxetine? * a MAO inhibitor b Noradrenaline reuptake inhibitor c Adrenergic agonist d Cholinergic agonist e Selective serotonin reuptake inhibitor 3 In Graded Dose-Response, which of the following parameters refers to the dose producing 50% of the maximum response? * a Potency b LD50 c Efficacy d Ceiling dose e ED50 4 Which of the following statements best describe a partial agonist? * a Interacts with more than one receptor type b Blocks the effect of the antagonist c Cannot produce the full effect even at high doses d Has low potency but high efficacy. e Has affinity but lacks efficacy 5 Which drug promotes transient muscle fasciculation followed by muscle paralysis that is not reversed by Neostigmine? * a Hyoscyamine b Rocuronium c Succinylcholine d…

Anaphylaxis Several people suffer from severe allergic reactions to things like nuts, seafood, or bee stings that cause their body to go into anaphylaxis.  Anaphylaxis is a serious and life-threatening allergic reaction where tissues of the tongue and throat can swell to close off the airway. Symptoms include swelling of the lips and tongue, shortness of breath, rapid pulse and fainting.   1. Identify a hormone that would rapidly alleviate these symptoms.  2. Explain how the hormone you identified would work in conjunction with the nervous system to alleviate symptoms of anaphylaxis.

1. Cortisol:   a. is made in the middle zone of the adrenal cortex   b. is a glucocorticoid   c. has an antiimmunity effect   d. all of the above   2. Protein hormones have hormone receptors in the cell:       a. both a and c above   b. membrane   c. nucleus   3. D.  cytoplasm     The difference between a three- and a two-neuron reflex is that a three-neuron reflex:   a. includes an efferent neuron   b. includes an afferent neuron   c. passes through the dorsal root ganglion   d. includes an interneuron

1. Explain the process of how your body uses hormones to increase body temperature when an individual experiences a drop in body temperature in her extremities. 2. Explain using an example how hormones can have an inhibitory response and why this would happen in the human body.  2-3 sentences for both, ASAP

. Endocrine disrupters Which of these toxic effects on humans are belong to the pesticides? 0290942 II. Carcinogenic effects III. Neurological effects IYEY O a. l-II 202909 O b. Only I O c. OnlyII O d. HII O e H-IL 202 NARGIZ GULI 2029 20290942 NARGIZ GULI NARGIZ GLTYEY

6. The doctor has ordered iiiss drams of Milk of Magnesia pc and hs. The stock supply is a 6 oz bottle. a. How many mL will you give for one dose? b. When will you give the Milk of Magnesia? c. How many total doses will be given in 1 day a. C. 7. The doctor has ordered Dopamine 3mcg/kg/min IV. You have an IV bag with 400 mg Dopamine in 200 ml D5W. The drop factor is 15 gtts/ml. The patient weighs 150 lbs. a. What is the flow rate in ml/hr? b. What is the flow rate in gtts/min? c. How many mg will the patient receive in 1 hour? b. a. C. b. C. 8. The doctor has ordered Ampicillin 750 mg. in 100 ml D5W to run over 30minutes q 6hr. The stock supply is a 1g vial with instructions to reconstitute with 4.5 ml NS for a final volume of 5 ml. The drop factor is 15 gtts/ml. a. How many ml will you add to the D5W for the correct dose? a. b. How many grams will the patient receive in 24 hours/ c. What is the flow rate in gtts/min? b. 9. The doctor orders 1000ml D5W IV to run over 12 hours. She also…

4. Which of the following primarily act on cell surface receptors? (select all that apply) a. steroid hormones   b. catecholamines   c. peptide hormones   d. none of the above 5. Which statement(s) is/are true based on the drawing above? (choose all that apply) a. the blue neurons could secrete cortisol   b. the green cells could be secreting insulin-like growth factors   c. a tertiary pathology occurs at the level of the blue neurons   d. negative feedback only occurs at the level of the blue neurons   e. the gold neurons are part of the portal system    f. the gold neurons could secrete oxytocin     6. Which of the following hormones is most likely to act for the longest period of time? a. ACTH   b. TSH   c. Cortisol   d. Dopamine   e. TRH 7. Which of the following is derived from an amino acid? a. Tyrosine   b. Epinephrine   c. Androstenedione   d. Prolactin 8. Based on the image above, the blue neuron is connected to the ______(a. anterior  b. posterior) pituitary and a possible…

3- Is not a side effects of α1-blockers? a.Nasal congestion b.Postural hypotension c.Raynaud phenomenon d.Delayed ejaculation

1. Which of the following makes it especially difficult for veterinarians to determine if an opioid is truly indicated? A. Opioids used in veterinary medicine are not used in human medicine B. Our patients can’t talk C. Our patients always require larger doses than humans D. All of the above   2. Which of the following is/are potential problems with PDMPs in veterinary medicine? A. Determining how to report the data B. Potential HIPPA violations when reviewing the system seeing the client’s medical information C. How to tie pets to the people that we are trying to monitor D. All of the above   3. Which schedule of controlled substance has no accepted medical use? A. CI B. CII C. CIII D. CIV   4. Which state specific regulatory agencies do you need to be familiar with to know how they regulate controlled substances at the state level? A. Local DEA Field Office B. State Board of Pharmacy C. State Veterinary Board D. All of the…

1. Define counterfeit drugs. 2. Explain the source of counterfeit drugs and how they are obtained. 3. Discuss the global problems caused by counterfeit drugs (include more than overdose issues) 4. What are the FDA and pharmaceutical companies doing? 5. How can you, the consumer, protect yourself and your lived ones.

48) Opioid receptor antagonist administration should be avoided in pregnancy unless absolutely needed, because death of the fetus could result from _______________. 48) Vasodilation Narcotic Withdrawal Malnutrition Acidity

1. Which of the following drugs is not a cardioselective beta-blocker? *A. EsmololB. AtenololC. PropranololD. MetoprololE. Bisoprolol 2. It is the ability of a drug to initiate cellular effects.A. AgonistB. AntagonistC. EfficacyD. Intrinsic Activity 3. What type of antagonism is exemplified when the interaction of two (2) drugs whoseopposing actions in the body tend to cancel each other’s effect?A. Physiological antagonismB. Pharmacokinetic antagonismC. Chemical antagonismD. Non-competitive antagonismE. Pharmacological antagonism 4. Which enzyme breaks down the neurotransmitter of the parasympathetic nerve?A. Catechol-O-Methyl TransferaseB. AcetylcholinesteraseC. Monoamine OxidaseD. DecarboxylaseE. CYP isozymes 5. Which drug exhibits similar mechanism of action with Reserpine? *A. VesamicolB. PilocarpineC. Botulinum toxinD. EpinephrineE. Neostigmine 6. Which of the following drugs is not a muscarinic-receptor antagonist used tocounteract cholinergic transmission? *A. UrecholineB.…

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11. Describe the functions of the following steroid hormones. a. Androgens b. Glucocorticoids c. Mineralocorticoids.

19. Which of the following is a biogenic amine that is (are) classified as a catecholamine? A .norepinephrine B. epinephrine C. adrenaline D. đopamine E All of the above F. A and B

10- A selective beta 1 antagonist used in emergency to reduce the hypertensive crisis is: a.Atropine b.Esmolol c.Acetylcholine d.Furosemide