TLC PLQ

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St. John Fisher College *

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240

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Chemistry

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Feb 20, 2024

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docx

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CHEM 240 • Laboratory Hobart and William Smith Colleges Modules Post Lab Questions (Fill out this document and submit electronically) Please make sure your answers are in blue! HW1. A student ran the following reaction: Match the following scenario with the representative TLC (sm= starting material, co = cospot, rxn= reaction pot) Scenario Answer 1. The reaction did not run to completion (not all sm was consumed) C 2. The reaction ran to completion (all starting material was consumed). D 3. The sm spot was run with too polar an eluent. B 4. The sm spot was run with too nonpolar an eluent E 5. No reaction has occurred. A 6. Too much sm was loaded onto the adsorbent F The student could make the eluent more polar. The amount of Hexane used could be lowered in comparison to the ethyl acetate mixture CHEM 240 Laboratory Post-Lab Materials
CHEM 240 • Laboratory Hobart and William Smith Colleges Modules (EtOAc) which would make the eluent more polar. The ratio could be 1:2 Hex:EtOAc or any other ratio where Hexane was in a lesser amount. By increasing the polarity of the eluent, the compound will be moved further up the plate, creating more separation. This is because the more polar eluent will interrupt CHEM 240 Laboratory Post-Lab Materials
CHEM 240 • Laboratory Hobart and William Smith Colleges Modules the intermolecular forces interacting between the compound and the absorbent allowing the compound to move mor HW2. A student ran the following TLC using 1:1 Hex:EtOAc and observed the TLC below. a. How might the student alter the eluent ratio to effect a better separation? Explain your reasoning. b. The student could make the eluent more polar. The amount of Hexane used could be c. lowered in comparison to the ethyl acetate mixture (EtOAc) which would make the eluent CHEM 240 Laboratory Post-Lab Materials
CHEM 240 • Laboratory Hobart and William Smith Colleges Modules d. more polar. The ratio could be 1:2 Hex:EtOAc or any other ratio where Hexane was in a e. lesser amount. By increasing the polarity of the eluent, the compound will be moved further f. up the plate, creating more separation. This is because the more polar eluent will interrupt g. the intermolecular forces interacting CHEM 240 Laboratory Post-Lab Materials
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