recrystallization - discussion_questions_v4

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Chemistry

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Dec 6, 2023

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CHEM 237 Discussion Questions – Recrystallization Name: Mariam Altamimi Date: 9-16-23 Section: CHEM 237- TA Name: Edward Lee Discussion Questions should be submitted through Gradescope. 1. (4 points total) You wish to purify an unknown, compound A , by recrystallization. You test six solvents and record the following observations. Solubility of Compound A (10 mg / 0.25 mL solvent) Solvent Solubility (0 °C) Solubility (100 °C) Observations Good or Poor? Water Insoluble Soluble Slow crystallization on cooling poor n -Hexane Insoluble Insoluble Compound was insoluble poor Toluene Insoluble Soluble Rapid crystallization on cooling poor Ethanol Insoluble Soluble Slow crystallization on cooling poor Methanol Insoluble Soluble Slow crystallization on cooling good 70% Ethanol Soluble Soluble No crystallization on cooling poor a. (3 points) In the last column, rank each solvent as a good or poor choice for the recrystallization of compound A . b. (1 points) A lab technician narrows down the structure of compound A to one of five possibilities. Circle any compound(s) that can be immediately disqualified based on the table above Aromatic and aromatic
CHEM 237 Discussion Questions – Recrystallization 2. (4 points total) Compound B is contaminated with small amounts of compounds C and D . The recrystallization process is summarized by the following flow chart. a. (1 point) The initial mixture ( compound B + compounds C and D ) has a recorded mass of 2.35 g. After step 5 , 1.89 g of compound B is obtained. Calculate the percent recovery. % recovery = (amount of substance actually collected)/(amount of substance supposed to collect) % recovery = (1.89 g / 2.35 g) x 100 = 8.42 % % recovery = 8.42% b. (1 points) Is step 3 (hot vacuum filtration) necessary? Briefly (2 sentences) explain your answer, including any potential risks of including this step (if unnecessary) or removing it (if necessary). Step 3 (hot vacuum filtration) is necessary because its the process of removing impurities from the solution to obtain the pure crystals. Potential risks of removing this step include the impurities not getting filtered properly and efficiently as solids tend to soluble at warmer temperatures.
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