Molec Biochem Chapter 6 Flashcards _ Quizlet
.pdf
keyboard_arrow_up
School
Simon Fraser University *
*We aren’t endorsed by this school
Course
232
Subject
Chemistry
Date
Dec 6, 2023
Type
Pages
19
Uploaded by KidDiscoveryMouse27
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
1/19
Try the fastest way to create flashcards
Molec Biochem Chapter 6
12 studiers today
4.7 (3 reviews)
Students also viewed
Terms in this set (78)
Others also viewed these textbooks
Search for a textbook or question
Organic Chemistry
3rd Edition
•
ISBN: 9781119340577
David Klein
3,098 solutions
Protein Structure Part 1
37 terms
winterch
Preview
Chapter 6 Part 2
30 terms
ameliadelm
Preview
Biochem Ch. 5
22 terms
Cerina_James
Preview
proteins
30 terms
TheInsan
Which one of the following statements about
peptide bonds is FALSE. Peptide bonds are:
-charged.
-covalent.
-involved in forming the primary structure of
proteins.
-amides.
-rigid and planar, with partial double-bond
character.
charged.
Which of the following describes the entire three-
dimensional structure of a single polypeptide?
Tertiary structure
Quaternary structure
Primary structure
Secondary structure
Tertiary structure
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
2/19
Which of the following amino acid residues form
hydrogen bonds with Ala residues located in an
alpha-helix?
-Polar residues involved in the stabilization of
tertiary structure.
-Residues located within the same -helix.
-Residues in a neighbouring -helix.
-None, because Ala is unable to form hydrogen
bonds.
Residues located within the same -helix.
A domain is:
-a folded segment of polypeptide with -a separate
hydrophobic core.
-an -helix, β
-sheet or irregular secondary structure.
-the same as a protein's tertiary structure.
-always a motif.
a folded segment of polypeptide with -a separate hydrophobic core.
Which level of protein structure is defined as "the
hydrogen bonded arrangement of the polypeptide
backbone"?
Which level of protein structure is defined as "the
hydrogen bonded arrangement of the polypeptide
backbone"?
Secondary
Tertiary
Quaternary
Primary
Secondary
Where are irregular secondary structures (loops)
generally found in soluble globular proteins and
why?
-On the surface so that they can interact with the
solvent.
-On the surface because they are less compact.
-In the core of the protein so that they can interact
with hydrophobic groups.
-In the core of the protein because they connect β
-
strands and -helices.
On the surface so that they can interact with the solvent.
Which of the following statements about quaternary
structure is TRUE?
-Quaternary structure is defined as the 3D structure
of proteins with four subunits.
-Quaternary structure requires covalent interactions
between polypeptide chains.
-Quaternary structure is stabilized by the same
types of noncovalent interactions as tertiary
structure.
-Quaternary structure exists only in proteins
containing prosthetic groups.
Quaternary structure is stabilized by the same types of noncovalent interactions as
tertiary structure.
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
3/19
Which of the following series of amino acids is most
likely to be buried in the center of a water-soluble
globular protein?
Pro, Gln, His
Gly, Asn, Ser
Glu, Asp, Lys
Ala, Leu, Phe
Ala, Leu, Phe
Which of the following statements about peptide
bonds is FALSE?
-Water is released when a peptide bond is formed.
-The peptide bond exhibits partial double bond
character
-The peptide bond has restricted rotation around
the bond between the carbonyl carbon and C.
-The peptide bond is planar.
The peptide bond has restricted rotation around the bond between the carbonyl
carbon and C.
Which one of the following sequences of five amino
acids would most likely be located in the interior of
a water soluble globular protein?
Tyr-Phe-Glu-Asn-Leu
Met-Phe-Pro-Ile-Leu
Glu-Asn-Ser-Thr-Gln
Val-Ala-Val-Glu-Val
Met-Phe-Pro-Ile-Leu
Compare the -helix with the structure of double-
stranded DNA. Which statement is TRUE for both
structures?
-The backbones are on the outside of the helix.
-The hydrogen bonds are perpendicular to the axis
of the helix.
-Hydrogen bonds are the primary determinant of
stability.
-The helices are right handed.
The helices are right handed
Which one of the following statements about the β
-
sheet is FALSE?
-The side chains in a β
-sheet alternate between the
two sides of the sheet.
-The β
-sheet is a type of regular secondary
structure.
-The β
-sheet is a type of secondary structure that
fulfills the hydrogen bonding requirements of
amino acid side chains.
-The β
-sheet contains hydrogen bonds between
the carbonyl oxygen of one residue and an amide
hydrogen of a residue on an adjacent strand.
-
β
-sheets can be parallel or antiparallel.
The β
-sheet is a type of secondary structure that fulfills the hydrogen bonding
requirements of amino acid side chains.
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
4/19
See an expert-written answer!
What ultimately determines the unique three
dimensional structure of soluble globular proteins?
-The number of subunits.
-The exact number of disulfide bonds.
-The exact number of H-bonds.
-The sequence of the amino acid residues.
-The prosthetic groups.
The sequence of the amino acid residues.
Which of the following sequences of amino acids is
most likely to be at the surface of a water-soluble
globular protein?
Pro-Phe-Thr
Ala-Leu-Phe
Gly-Tyr-Val
Glu-Asp-Lys
Ile-Ser-Met
Glu-Asp-Lys
Which of the following stabilizes the folding of a
polypeptide backbone into regular secondary
structure?
Disulphide bridges.
Hydrogen bonds.
Covalent bonds.
Electrostatic interactions.
Hydrophobic interactions.
Hydrogen bonds.
Which of the following statements about quaternary
structure is FALSE?
-Quaternary structure is defined as the
arrangement of polypeptide backbones in proteins
with four subunits
-Quaternary structure exists only in proteins
containing more than one polypeptide
-Quaternary structure is fine-tuned by ion pairs,
disulfide bonds, and hydrogen bonds.
-Quaternary structure is stabilized primarily by
hydrophobic interactions.
Quaternary structure is defined as the arrangement of polypeptide backbones in
proteins with four subunits
Which one of the following statements about the -
helix is FALSE?
-Side chains are located on the outside of an -helix.
-The -helix contains hydrogen bonds between the
carbonyl oxygen of one residue and an amide
hydrogen that is four residues closer to the carboxy
terminus of the helix.
-The -helix has a right handed twist.
-The -helix is a type of secondary structure that
fulfills the hydrogen bonding requirements of
amino acid side chains.
-The -helix is a type of regular secondary structure.
The -helix is a type of secondary structure that fulfills the hydrogen bonding
requirements of amino acid side chains.
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
5/19
Which of the following is TRUE about prosthetic
groups?
-Prosthetic groups are bound and released by the
protein as needed.
-Prosthetic groups are an integral part of the three
dimensional structure of the protein.
-Prosthetic groups are amino acids with additional
reactivity.
-Prosthetic groups are inorganic.
Prosthetic groups are an integral part of the three dimensional structure of the
protein
Which of the following is FALSE with respect to β
-
sheets?
-
β
-sheets may be parallel or anti-parallel.
-Strands in a β
-sheet are connected by irregular
loops.
-
β
-sheets are stabilized by non-covalent forces.
-Amino acid side chains protrude from one side of
the β
-sheet.
Amino acid side chains protrude from one side of the β
-sheet.
Which of the following statements about prosthetic
groups is INCORRECT?
-Heme is an example of a prosthetic group.
-Prosthetic groups increase the inherent chemical
reactivity of proteins.
-Prosthetic groups are not amino acids.
-Prosthetic groups form an integral part of the
secondary structure of proteins.
Prosthetic groups form an integral part of the secondary structure of proteins.
Which of the following statements about the -helix
and β
-sheet are TRUE?
1. They are both types of secondary structure.
2. They are both stabilized by hydrogen bonds
between amino acid side chains.
3. The polypeptide backbone is fully extended in
both structures.
4. They are both usually located in the interior of
soluble globular proteins.
1 and 4
Which of the following statements about the
peptide bond is FALSE?
-It is a bond that displays resonance.
-It is a phosphodiester bond.
-It exhibits partial double bond character.
-Atoms of the peptide bond are located in a single
plane.
-It is formed when water is released from the
condensation of an amino group and a carboxylic
acid.
It is a phosphodiester bond.
11/27/23, 9:05 AM
Molec Biochem Chapter 6 Flashcards | Quizlet
https://quizlet.com/28169216/molec-biochem-chapter-6-flash-cards/
6/19
Which of the following statements is TRUE
regarding the R-groups of amino acid residues in an
-helix?
-They are found on the exterior of the helix.
-They alternate between the outside and the inside
of the helix.
-They form the hydrogen bonds that produce the
helix.
-They are found in the interior of the helix.
-They cause the helix to be right handed.
They are found on the exterior of the helix.
Which of the following statements is FALSE?
-Both -helices and β
-sheets have conformations
that minimize steric strain in the polypeptide
backbone.
-Both -helices and β
-sheets have R groups that are
oriented away from the core of the structure.
-Both -helices and β
-sheets form only from
adjacent amino acid residues in the polypeptide.
-Both -helices and β
-sheets are stabilized by
hydrogen bonds between groups in the
polypeptide backbone
Both -helices and β
-sheets form only from adjacent amino acid residues in the
polypeptide.
You have been shown the detailed 3-D structure of
an unknown protein. The information indicates that
the protein's non-polar amino acid side chains are
all exposed on the surface, whereas its polar side
chains are all "buried" in the interior. What can you
conclude about this protein?
-It is likely to be a peripheral membrane protein
-It is likely to be a lipid-linked membrane protein.
-It is likely to be a soluble cytosolic protein.
-It is likely to be an integral membrane protein.
It is likely to be an integral membrane protein.
Why do Tyr and/or Trp residues tend to destabilize
an -helix when they occur next to each other in a
protein?
-The R group of neither amino acid can form a
hydrogen bond.
-There is steric hindrance between the bulky Tyr
and/or Trp side chains.
-There are possible covalent interactions between
the Tyr and/or Trp side chains.
-Both amino acids are highly hydrophobic.
-There is electrostatic repulsion between the Tyr
and Trp side chains.
There is steric hindrance between the bulky Tyr and/or Trp side chains.
Your preview ends here
Eager to read complete document? Join bartleby learn and gain access to the full version
- Access to all documents
- Unlimited textbook solutions
- 24/7 expert homework help
Related Questions
Complete the following reaction:
27Al13 + α → 30P15 P + __[a]_____
arrow_forward
SS C
cm 1 GtG tC
FCX
in
SH
U njmpLGQQmzAe4FI77iAeY/edit#slide%-id.g112e600b836_0_44
个
Help Accessibility
Last edit was 2 hours ago
Arial
21
BIUA
work Day 1-
18
What were some potential
human errors that could
have occurred when
calculating the mass before
and after the reaction?
Add these to your drawing
on page 60.
arrow_forward
lonization radiation usually affects molecules in human cells like:
glucose
water
DNA
lipids
arrow_forward
altérnative universe below to answer the questions{
Key
Symbol
1A
2A
8A
ЗА
Atomic
1
C
1
Number
W
Zy
4A
5A
6A
4.
ZA
G
K
V
M
7
8
Ad
10
11
12
13
14
15
Ac
Ab
Ах
H.
23
16
17
18
19
20
21
22
Y
R
24
25
26
B
27
28
29
30
31
1. If you have 36 moles of R, how many moles of FR2 will be produced?
moles
3 FAD2 +2 R
F3R2 +2 Ad
O LNC
arrow_forward
Dr. X claims that she has found a new remedy (carrot extract) to cure acne. She scores an interview with the science writer for a local newspaper, and gets a brief article written about her and her claims in that newspaper. The article does not contain any experimental evidence, but mentions that Dr. X accidentally splashed some carrot extract on her face and found that the acne was reduced a few days later. Student Y finds the article and cites it as a source for a paper he is writing for class, as evidence that acne has been cured.
(a) Is this finding a fact, a theory, a hypothesis, or an observation? Explain why you think so.
(b) Was it OK for Student Y to use the newspaper article as evidence for his paper? Explain why or why not.
arrow_forward
1. I want to know where all the alpha carbon is for #2
2. What are the intermediate(s) for both 1 and 2?
arrow_forward
Subject:! Cheme
arrow_forward
When reactor 4 at the Chernobyl Nuclear Power Station in Ukraine exploded at 1:23 p.m. on April 26, 1986, a great plume of radioactive isotopes erupted into the air and spread for thousands of miles. Most of the isotopes emitted immediately following the blast were of the element iodine. Which of the glands of the endocrine system would be most seriously—and immediately— affected by the blast, and how do you think this would become evident in the nearby population?
arrow_forward
Cuántos hidrógenos alfa tiene el siguiente compuesto?
A 9
B 12
©
C) 4
D 8
E 3
0
arrow_forward
Please help
arrow_forward
30)
'N-
?
?
arrow_forward
Complete the following reaction
arrow_forward
Complete the following reaction
arrow_forward
help me asap pls for number 7 less than 30 mins only i still have other things to do i'll give you an upvote after solving it
arrow_forward
Use a schematic diagram with explanations as to how you will carry out damage control and risk assessment based on your given scenario using the NFPA symbol.
arrow_forward
Assign R/S for carbon 13. I
Attachments
Но
A. R
B. S
ОН
3
ОН
IS
16
О
12
О
II
10
ОН
||
arrow_forward
5:31 PM Wed Mar 15
Question 25 of 75
The radioisotope ¹4C (half life = 5730
years) is used for carbon dating. What is
the first order rate constant for ¹4C?
Tap here or pull up for additional resources
1
4
7
+/-
1/years
3
5 6
9
2
LO 00
8
LTE 10%
Submit
X
C
x 100
arrow_forward
ilm/takeAssignment/takeCovalentActivity.do?locator=assignment-take
The radioisotope phosphorus-32 is used in tracers for measuring phosphorus uptake by plants.
The half-life of phosphorus-32 is 14.3 days. If you begin with 74.8 milligrams of phosphorus-32, how many milligrams will you have left after 42.9 days have passed?
mg
Submit Answer
[Review Topics]
[References]
Use the References to access important values if needed for this question.
Retry Entire Group
9 more group attempts remaining
Cengage Learning | Cengage Technical Support
(Pro
Previo
arrow_forward
Arsenic-74 is a radioisotope used for locating brain tumors. If t1/2 of arsenic-74 is 18 days, how much of a 120 mg sample remains after 90. days?
3.8 mg
60. mg
12 mg
18 mg
5.0 mg
arrow_forward
The wow expert Hand written solution is not allowed.
arrow_forward
If H (t) is the amount in (mg) of Heparin in a patient, at time t. The patient is being
dosed at a rate of 4 mg/hour, and the Heparin is broken down with a half-life of 1.4
hours in the body.
Which of the following is true?
Hint: use the balance law:
dH
dt
dH
dt
=
dH
dt
dH -
dt
4 — e-0.5t
= 4t - 0.5H
Net rate of change = rate in - rate out
4 - 0.5H
= 4t
e
-0.5t
arrow_forward
Answer question 7 please
arrow_forward
24Na decays β- with a half-life t1/2=15 hours. A solution containing 0.050 μCi of 24Na is injected into a patient's artery. After 4.5 h the patient is taken a blood sample containing 8 pCi/cm3. What does 24Na decay to? Assuming no biological elimination, calculate the liters of blood in the patient.
arrow_forward
Just include the solution/computation and answer. No need to explain in words.
arrow_forward
Calculate how long it will take for the amount of radionucleotide in each sample to decrease to 1/16 of the initial amount
arrow_forward
Try Again
Your answer is wrong. In addition to checking your math, check that you used the right data and DID NOT round any intermediate calculations.
A certain drug has a half-life in the body of 3.5 h. Suppose a patient takes one 300. mg pill at 7:00PM and another identical pill 45 min later. Calculate the
amount of drug left in his body at 10:00PM.
Be sure your answer has a unit symbol, if necessary, and round it to 3 significant digits.
559. mg
x10
X
arrow_forward
Please help
arrow_forward
8m2 = (014
Hula
AC₁A/+C-OH → ?
d
I
In that is the Product Form
7100
glaz
Genius
Page:
Date: / 1
arrow_forward
Choose the expected major product or products for the following reaction that involves a radiolabeled reactant
arrow_forward
Calculate how long it will take for them out of radionucleotide each sample to decrease to 1/8 of the intitial amount.
arrow_forward
SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry: Matter and Change
Chemistry
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Glencoe/McGraw-Hill School Pub Co
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Chemistry & Chemical Reactivity
Chemistry
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:Cengage Learning
Related Questions
- Complete the following reaction: 27Al13 + α → 30P15 P + __[a]_____arrow_forwardSS C cm 1 GtG tC FCX in SH U njmpLGQQmzAe4FI77iAeY/edit#slide%-id.g112e600b836_0_44 个 Help Accessibility Last edit was 2 hours ago Arial 21 BIUA work Day 1- 18 What were some potential human errors that could have occurred when calculating the mass before and after the reaction? Add these to your drawing on page 60.arrow_forwardlonization radiation usually affects molecules in human cells like: glucose water DNA lipidsarrow_forward
- altérnative universe below to answer the questions{ Key Symbol 1A 2A 8A ЗА Atomic 1 C 1 Number W Zy 4A 5A 6A 4. ZA G K V M 7 8 Ad 10 11 12 13 14 15 Ac Ab Ах H. 23 16 17 18 19 20 21 22 Y R 24 25 26 B 27 28 29 30 31 1. If you have 36 moles of R, how many moles of FR2 will be produced? moles 3 FAD2 +2 R F3R2 +2 Ad O LNCarrow_forwardDr. X claims that she has found a new remedy (carrot extract) to cure acne. She scores an interview with the science writer for a local newspaper, and gets a brief article written about her and her claims in that newspaper. The article does not contain any experimental evidence, but mentions that Dr. X accidentally splashed some carrot extract on her face and found that the acne was reduced a few days later. Student Y finds the article and cites it as a source for a paper he is writing for class, as evidence that acne has been cured. (a) Is this finding a fact, a theory, a hypothesis, or an observation? Explain why you think so. (b) Was it OK for Student Y to use the newspaper article as evidence for his paper? Explain why or why not.arrow_forward1. I want to know where all the alpha carbon is for #2 2. What are the intermediate(s) for both 1 and 2?arrow_forward
- Subject:! Chemearrow_forwardWhen reactor 4 at the Chernobyl Nuclear Power Station in Ukraine exploded at 1:23 p.m. on April 26, 1986, a great plume of radioactive isotopes erupted into the air and spread for thousands of miles. Most of the isotopes emitted immediately following the blast were of the element iodine. Which of the glands of the endocrine system would be most seriously—and immediately— affected by the blast, and how do you think this would become evident in the nearby population?arrow_forwardCuántos hidrógenos alfa tiene el siguiente compuesto? A 9 B 12 © C) 4 D 8 E 3 0arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Chemistry: Matter and ChangeChemistryISBN:9780078746376Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl WistromPublisher:Glencoe/McGraw-Hill School Pub CoIntroduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningChemistry & Chemical ReactivityChemistryISBN:9781337399074Author:John C. Kotz, Paul M. Treichel, John Townsend, David TreichelPublisher:Cengage Learning
Chemistry: Matter and Change
Chemistry
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Glencoe/McGraw-Hill School Pub Co
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Chemistry & Chemical Reactivity
Chemistry
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:Cengage Learning