CHEM_1131_LAB_REPORT_10_MA

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Durham College *

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1131

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Chemistry

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Jan 9, 2024

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4

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Experiment 10: VOLUMETRIC ANALYSIS OF ANTACID TABLETS Chemistry - 1131 By: Mohammad Shaikh Lab Partner: Sahil Khan Submitted to: Dave Duncan Date –November 27, 2023 Introduction: In this sedentary modern life and by overconsumption of meat products, humans are facing issues digesting all the food and several times it results in acidity. There are many types of antacid tablets available in the market. Here, one of the antacid tablets (Tums) is analyzed in the laboratory by doing titration by which one can understand how much 0.2M HCl (stomach acid) can be neutralized by 1 tablet of Tums. Objective: To determine the amount of HCl (in mEq) neutralized by 1 antacid tablet by titration with methyl orange indicator. Procedure: In this experiment, Tums tablet was crushed and placed into the Erlenmeyer flask which was then topped up to 50 ml of deionized water and stirred well. Full titration was done by filling 0.2M HCl in buret and using methyl orange as an indicator in the Erlenmeyer flask. Full procedure of the experiment is referred from Stathopoulos; Chemistry 1 Laboratory Manual; Durham College: Oshawa, 2023 ; p 36- 38. Note: 15 drops of methyl orange were used in the titration, because it was old, besides 10ml as mentioned in previously referred lab manual. Chemical Reactions: (1) 2HCl + CaCO 3 → CaCl 2 +H 2 O + CO 2 Observations: Table 1: Titration of Tums tablet (orange): First Trial Trial Initial Reading (mL) Final Reading (mL) Total amount Dispensed(mL) 1 (Orange Tablet) 0.02 50.00 49.98 0.95 49.90 48.95 0.90 12.65 11.75 7.40 22.50 15.10 So Total amount of HCl got neutralized was 49.98 +48.95 + 11.75+ 15.10 = 125.78 mL
At the end of the titration, Solution was pink with some ppt. at the bottom. Table 2: Titration of Tums tablet (white): (second trial) Trial Initial Reading (mL) Final Reading (mL) Total amount Dispensed(mL) 2 (white Tablet) 1.97 49.40 47.43 1.32 49.68 48.36 1.60 49.65 48.05 0.55 7.40 6.85 So, Total amount of HCl got neutralized was 47.43 + 48.36+ 48.05+ 6.85= 150.69 mL At the end of the titration, Solution turned pink with some ppt. at the bottom. Table 3: Titration of Tums tablet (white): (third trial) Trial Initial Reading (mL) Final Reading (mL) Total amount Dispensed(mL) 3 (white Tablet) 0.43 49.85 49.42 0.15 49.95 49.80 0.60 12.20 11.60 So Total amount of HCl got neutralized was 49.42 + 49.80 + 48.05+ 11.60= 110.82 mL At the end of the titration, Solution turned faint pink with some ppt. at the bottom. Calculation: 1. Average amount of HCl got neutralized. = addition of total amount of dispensed HCl / 3 =125.78+150.69+110.82 mL / 3 = 129.10 mL 2. To convert it in to mEq 129.10 mL × 0.2mol × 1000m / 1000mL = 25.81 mmol HCl For HCl, 1mmol of HCl = 1 mEq So, mEq = 25.81mEq
Discussion: Titration is a basic technique to do neutralization of acid and base. One can use this for practical use to find efficiency of antacid tablets which is generally getting used in large amount in the modern era. Student can do this by getting HCl of similar concentration as gastric acid and neutralize it by dissolving one antacid tablet with having methyl orange as indicator. By this experiment, 129.10 mL gastric acid did get neutralized which is 25.81mEq. Lab-Question: 1. Methyl orange shows clear and distinct color variance at various pH values which is essential in Titration. 2. Milk of Magnesia: Mg(OH) 2 + 2HCl → MgCl 2 + H 2 O Tums: 2HCl + CaCO 3 → CaCl 2 + H 2 O + CO 2 Eno: NaHCO 3 + HCl → NaCl + H 2 O + CO 2 Rolaids: NaAl(CO 3 )(OH) 2  + 4HCl → NaCl + AlCl 3  + CO 2  + 3H 2 O 3. 275mL 0.98M H + = 0.98mol/L × 275mL =269.50 mmol =269.50 mEq only 25.81mEq will be neutralized So, percentage of gastric acid which would get neutralized =25.81 mEq × 100 % / 269.50 mEq =9.577% Conclusion: In conclusion, one can see 25.81mEq of HCl got neutralized by the titration with methyl orange which fulfill the objective of the experiment.
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References: 1. Stathopoulos D; Chemistry 1131 Laboratory Manual; Durham College: Oshawa; 2023; p 36 - 38. 2. What is the role of methyl orange in acid base titration ; toppr.com ) ; (accessed date : 2023-12-04)