BIOS 255 Week 1 Case Study
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Dec 6, 2023
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Case Study: Coagulation
Dhruti Patel
BIOS 255
Professor Brener
Nov 5, 2023
1.
Discuss which clotting factors the PT and PTT test evaluate and whether each test
measures the intrinsic or the extrinsic pathways.
The Prothrombin Time (PT) test evaluates the extrinsic pathway of hemostasis. It
assesses the time it takes for blood to clot. This test is useful in detecting bleeding
disorders or abnormalities in the blood clotting process. The Partial Thromboplastin Time
(PTT) test measures the time required for blood to clot. It provides valuable information
about potential bleeding issues or irregularities in the blood's ability to coagulate
effectively.
2.
Describe the common coagulation pathway.
The common coagulation pathway is the final stage in the clotting cascade where the
intrinsic and extrinsic pathways converge. This pathway ultimately leads to the formation
of a stable blood clot. The common coagulation pathway involves the conversion of
prothrombin to thrombin and fibrinogen to fibrin. Thrombin is an enzyme that cleaves
fibrinogen into fibrin, forming a mesh that traps blood cells and forms a clot.
3.
Based on Jessie's test, which factor deficiency do you believe he has and why?
Based on Jessie's test results, it appears that he has a deficiency in Factor VIII, an
essential clotting protein.
4.
Jessie's clotting factor disease is seen more often in males. Please explain why.
The reason for this is the gene's location on the X chromosome. In males, they receive
one X chromosome from their mother, whereas females inherit one X chromosome from
each parent.
5.
If both the PT and the PTT tests were abnormally long, which part of the coagulation
pathway would be affected?
Deficiencies in both the intrinsic and extrinsic pathways would be affected, indicating
potential deficiencies in both pathways.
Reference
Lombardo, C. R. (2017, January 14). PT and PTT Blood Test Results Fully Explained.
HRF.
https://healthresearchfunding.org/pt-and-ptt-blood-test-results-fully-explained/
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Related Questions
Q.1
a. Repeatability and reproducibility are ways of measuring precision, particularly in the field of
engineering.
i.
What is an engineer's expectation when performing repeatability or reproducibility?
ii.
State a difference between repeatability and reproducibility in an experiment?
b. Figure Q.1 shows the measurement data of two types of thermal transducers namely thermocouple.
Турe E
Туре К
6.8
4.2
20
40
60
80
100
Temperature Difference (°C)
Voltage Output (mV)
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Don't use chat gpt
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Macro farms Ltd can purchase two types of fertilizer which contain the following percentage
Nitrate Phosphate Potash
Type X 18 5 2
Type Y 3 2 5
For certain type of crop, the following minimum quantities (kg) are required Nitrate Phosphate Potash
100 50 40
Type X cost GHS10 per kg and type Y cost GHS5 per kg. The company currently buys 1,000 kg of each type and wishes to minimize it expenditure on fertilizers.Required
1. What is the minimum expenditure that can be incurred on fertilizer?
2. Find the savings the company can make by switching from it current policy to your recommendation.
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10:45 PM | 5.7KB/s
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expert.chegg.com/ex
Chegg
+
Time remaining: 00:06:48
Vo 4G+
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Answer Skip Exit
10
26
Chemistry
1. You are throwing a fondue party! You need to
heat 800.0 mL of vegetable oil from 20 to 190.0°C
using an ethanol burner. Assuming a perfect
transfer of heat from the burner into the oil, what
mass of ethanol would be required (Note -
ethanol has a molar enthalpy of -1277 KJ/mol)?
Assume your kitchen is at SATP, vegetable oil has
a density of 0.920 g/mL and the specific heat
capacity of vegetable oil is 2.000 J/g °C.
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A research team is interested in the difference between serum uric acid levels in patients with and without Down's syndrome. In a
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mg/100 ml. In a general hospital a sample of 15 normal individuals of the same age and sex were found to have a mean value of 3.4
mg/100 ml. If it is reasonable to assume that the two populations of values are normally distributed with variances equal to 1 and 1.5,
find the 95 percent confidence interval. (3 decimal places)
lower limit =
upper limit =
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The simple dynamic method is used to measure kļa in a fermenter operated at 30 C and 1 atm
pressure. Data for the dissolved oxygen concentration as a function of time during the reoxygenation step
are as follows:
Time (s)
CAL (% air saturation)
10
43.5
15
53.5
20
60.0
30
67.5
40
70.5
50
72.0
70
73.0
100
73.5
130
73.5
(a) Calculate the value of kla.
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O Estimate the MRR (in cc/sec) of an alloy containing
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ECM with current of 500 ampere. The density of
the alloy is 8.28 g/cc. The following data is
available.
Metal
Gram atomic weight Velency
Cobalt
58.93
Nickel
58.71
2
Chromium
51.99
Assume Faraday's constant is 96500 coulombs/
mole.
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ANSWERS ARE DOWN BELOW
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9:43 am Fri 24 Dec
* 62%
+ : 0
King Abdul Aziz University
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Aero. Eng. Dept
Faculty of Engineering
Assignment 6
I/II law, Entropy, Cycles
Handwritten assignment. Detailed answers are expected. Use your university ID.
What is a pure substance? Write any four examples of pure substance. Draw tv and Pv diagram of
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Give their examples. Write the values of cp, cv, R, and y for air and combustion products.
1.
2.
3.
A 0.2 m³ vessel contains 120+last two digits kg of water at 90 ° C. Determine pressure, specific and
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A vessel contains 10 kg of water at 200 kPa. Determine pressure, specific and total internal energy,
specific and total enthalpy, and specific and total entropy. Consider 5 different cases/states:
T= 30 ° C
4.
а.
b. T= Tsat…
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e ll 42% A 16:33
docs.google.com/forms
59
A musical note on a piano has a
frequency of 31 Hz. If the tension in
the 2-m string is 308 N, and one-half
wavelength occupies the string, what
is the mass of the wire?
0.031 kg
0.040 kg
0.047 kg
0.019 kg
0.024 kg
A simple pendulum is set into motion
at two different times with different
initial conditions. The first time: the
bob is in its equilibrium position and
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12:30
Done
Edit
A 24.6 2 resistor found
experimentally. in Ohm's law
experiments, if its actual
value is equal to 24 Q, then
the percentage error in R is
Select one:
a. 0.025%
b. 2.5 %
c. 3.3%
d. 0.033%
Loay Aljboor
2020/11/13
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2.
For each of the situations described below, use an initial value problem to
model the situation. Clearly define any variables and functions used. Do not solve the
initial value problems.
a. A 60kg ball is released from rest 3km above the Earth. Its drag force has a
proportionality constant of 50 . Model its velocity as a function of time.
m
b. Air conditioning is turned off in an empty building. Initially, at 6PM, it has an interior
temperature of 60°F. The building has a time constant of 4 hours. (Note: This is the
time constant, not the constant of proportionality in Newton's Law.) The outdoor
temperature fluctuates sinusoidally, reaching a maxmimum of 100°F at noon and a
minimum of 60°F at midnight every day. Assume there are no heating or cooling
effects on the build aside from Newton's Law of Cooling. Model the building's
temperature as a function of time.
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What is Qh and Qc based on the table
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to use Animated Figure.
(a) i
°C
(b) і
°C
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/ 14
+ | B O
78%
Fig. T(a)
(b)
Answer each of the following for the circuit shown in Fig. 1(b) when the spring in valve 1S3
fails (will not extend) after the first activation of valve 1S3.
Describe the problem that would result for the second and subsequent activations of
(ii)
What is the name given to this type of problem?
1A
182
183
課
1V2
1V1
1S2
1S3 2
1S12
Fig. 1(b)
(c)
Identify two reasons why indirect control would be used instead of direct control in
electropneumatics.
(d)
Name the different types of hydraulic relief valves and state the main operation difference
Smarks)
between the two types.
Page 2 of 14
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After drying.
Sampling
Time
(min.)
0
60
180
360
Experimental results for amount of SS remaining in the sample (mg/l)
Sampling depth (cm)
100
230
150
118
90
200
230
150
143
115
300
230
159
147
134
400
230
157
152
145
The sewage treatment work incorporates two primary settlement tanks each of a diameter of 25 m.
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Q
Question 2: The acceleration function of an object doing
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is in s. If its initial velocity vo 8i m/s, and initial position
is at the origin, determine the magnitude of its velocity
when t = 3 s.
=
(a) 2.57 m/s
Asiacell .
(b) 4.06 m/s
(c) 14.7 m/s
(d) 10.3 m/s
Quartion 3: The acceleration function of an object doing
تم
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Immediately after the jump, the x and y locations of her hip can be described
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where x and y are expressed in feet and t is expressed in seconds.
by x(t) = 20t+0.2 sin (4t) and y(t) =
(¹),
3
3
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t = 2 s.
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A quartz mixture is screened
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screen. The mass of feed,
oversize and undersize are
given below in the table.
MeshDiameter
Mass (kg)
No.
(mm) FeedoversizeUndersize
3.3
5
8
2.4
24
10
1.7
38
49
19
14
1.2
25
15
36
20
0.8
15
25
28
0.6
3
1
35
0.4
3
6.
65
0.2
Pan
3
Calculate screen
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Sling Psychrometer Readings (use the table on the next page to find the Relative Humidity)
Trial
Outside conditions
Wet Bulb Temperature
Dry Bulb Temperature
Relative Humidity %
1
Mostly Sunny
14 C
20 C
2
Partly cloudy
16 C
20 C
3
Sunny
10 C
22 C
4
Cloudy
22 C
22 C
PART A: Using the data above, if the Dry and Wet Bulb Temperatures are close to each other, what does that mean about the Relative Humidity? What does the Dry Bulb Temperature relate to? On a day that it is sunny outside, would you expect the wet and dry bulb temperature to be close to, or far from each other?
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MTH004- MAIN- TERM 2- SEMESTER 1 2020 -2021
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كلية عمان البحرية الدولية
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(7)
Question 1
If a manufacturer sells x units of a certain product, revenue R and cost C (in dollars) are given by
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use the fact that Profit = Revenue - Cost to determine the number of units the manufacturer should
sell to enjoy a profit of at least $2400.
FMT
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