A Brief Look at Neurofibromatosis

534 Words Feb 16th, 2018 2 Pages
In human, there are 23 pairs of chromosomes (22 autosomal pairs and 1 pair of sex chromosomes), our chromosomes are organized into short segments of DNA called genes, and these genes make up our chromosomes. Our chromosomes can tell us if we have a disease or not, certain disease appear in certain chromosomes that help us determine what type of genetic disease the disease is. Variations of our genes are called alleles, having 2 alleles for each gene. When we use alleles when we consider genetic diseases’ allele is dominant or recessive. Neurofibromatosis is a genetic disorders of the nervous system, it can be passed by a parent or it can happen because of a mutation (change) in your genes. This diseases has three cases, neurofibromatosis type 1 (NF1) and type 2 (NF2) and rarely schwannomatosis. NF is considered an autosomal dominant disease, which means that people with this condition only need to have one mutated gene. Because the disease is dominant it than means that the affected person only needs the one allele. NF disorders are genetic disorders that affect how nerve cells form and grow, causing tumors. The three types of NF are classified on where the tumor grow and the symptoms and which genes they affect. In the disease the NF1 gene is located on the long arm of chromosome 17. Overall when considering an affected…

More about A Brief Look at Neurofibromatosis

Open Document