A Brief Note On Arthritis And Musculoskeletal And Skin Disease

"Rheumatoid joint inflammation is an interminable infection set apart by irritation of the joints, frequently influencing the hand joints and both sides of the body in the meantime" (Royal Australian College of General Practitioners, 2009).

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid Arthritis has been subject of numerous studies and researches in the look for a better understanding of how it effects the individuals diagnosed with it. There is a higher incident of females diagnosed with RA than male as well as a relationship with genetic and environmental factors involved. Around one percent of the world population is affected by RA; therefore, diverse studies have been performed to understand how the lives of the diagnosed patients can be impacted by the disease. For example, how RA affects the mobility, safety and activities of daily living in general as well as the development of interventions to better approach RA. On

Rheumatoid arthritis is one of the incurable diseases and turns chronic with progressive inflammatory of the synovial lining of peripheral joins. It is characterized by symmetric, chronic, and deforming polyatrhitis that causes long term joint disability when not controlled early. Considering there is no cure for this disease, management focuses on pain and inflammation reduction in order to prevent destruction of joints while at the same time preserving and improving on the functionality of the patient (Varatharajan et al, 2009).

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Arthritis related statistics 2006, Division of Adult and Community Health, Health Care and Aging Studies Branch, National Center for Chronic Disease Prevention, and Health Promotion, 2006.

Joint stiffness may develop after long periods of sleeping or sitting. Nodules ranging in size develop in nearly one-third of people who have rheumatoid arthritis. Nodules usually develop on the elbows, knuckles, spine, and lower leg bones. Weight loss and a low-grade fever can also occur. Rheumatoid arthritis results in the destruction of cartilage in the joints, targets the synovial lining of joints and can damage the lungs, heart and the blood vessels. It occurs when your immune system attacks the synovium which is the lining of the membranes that surround your joints. The inflammation that results thickens the synovium, and can also destroy the cartilage and bone within the joint. The tendons and ligaments that hold the joint together get weak and stretch. This process causes the joint to lose its shape and joint

The main cause doctors have found is that the immune system attacks the human body and starts to destroy the bones (Arthritisorg, 2015). Because the body is sensing an attack, heavy swelling occurs. The inflammation, even though it is healthy to help recover and maintain homeostasis, leads to painful swelling. With too much inflammation, the synovial- the lining membrane that covers the joints- hardens, cartilage and ligaments are destroyed, and the structure of the bones loosens (Arthritisorg, 2015). In the bloodstream, researchers have found that patients with rheumatoid arthritis have a higher percentage of HLA (controls the immune system); have more STAT4 (regulates the immune system); and have more PTPN22 (develops rheumatoid arthritis) (Arthritisorg, 2015). Still today, doctors are trying to find more answers for this non-stopping

Rheumatoid Arthritis is a systemic autoimmune disorder. There are more than 100 different types of Arthritis, yet it is estimated that it affects approximately 1% of the population in the Western World. The disease is generally diagnosed in middle aged adults and the elderly. In rarer cases, children can also develop the disease and it is called Juvenile Rheumatoid Arthritis. Women are three times more likely to have rheumatoid arthritis than men. (Stevens) Many people living with Rheumatoid Arthritis appear to be healthy individuals, but suffer internally. Today, I will discuss what rheumatoid arthritis is, how it is diagnosed, and how it affects the body.

Rheumatoid arthritis (RA) is an autoimmune disease that affects the cartilage in one 's joints, it is not curable, it can not be stopped, only the pain itself can be lessened. In an average person’s body, the immune system has one job; to attack foreign substances that may enter the body. With the 1.5 million people in the United States that have been diagnosed with rheumatoid arthritis, their bodies are “tricked” or mislead into thinking that the cartilage within their joints is what is foreign. Once their immune system attacks the joints, it causes inflammation within, which then in turn leads to the synovium (lining of the joints) tissue to thicken. The synovium makes a fluid that acts as a lubricant to the joints and helps everything move freely. Once that fluid is gone, swelling and pain is experienced next. After awhile, the cartilage within the joints begins to disintegrate and will eventually cripple the individual. Along with knowing exactly what RA is, by the end of this paper you will know signs and symptoms within the oral cavity and systemically, and you’ll be familiar with how nutrition is related to the progression of this disease.

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.

RA is a chronic, systemic and inflammatory disease that progressively impacts peripheral joints (Panayi 2011).The damage that occurs is predominantly symmetrical and polyarthropathic (Rindfleisch & Muller 2005). It affects the host’s joint synovial membranes, tendon sheaths and bursae and causes stiffness, pain and swelling to the joints

Synovial macrophages and fibroblast-like synoviocytes increase in number and infiltrate the surrounding cartilage and bone; these cells are the primary source of inflammatory mediators, involving proinflammatory cytokines, chemokines, and adhesion molecules. The cytokine tumor necrosis factor alpha (TNF alpha) is present in the RA synovium, and so anti-TNF alpha therapy has proved to be effective in controlling disease progression in many RA patients (76).

Rheumatoid arthritis is an autoimmune and systemic disease damaging many joints in all parts of the body. In this state, body’s immune system activates a self-regulated immunological cascade that ultimately leads to joint damage. Rheumatoid arthritis begins in synovial tissues attached to the joints and then extends towards cartilage. It is described by