A Brief Note On Atherosclerosis And Coronary Spasms

866 WordsApr 11, 20174 Pages
1. Ms. T sought medical attention mainly because of intolerable chest pain after climbing several flights of stairs; however, Ms. T has a history of conditions such as atherosclerosis and coronary spasms. Atherosclerosis is the buildup of fatty material known as plaque, along the walls of arteries causing the arteries to narrow (Taber’s pg 224). Therefore, angina pectoris can result with exertion. Also, coronary spasms can potentially be caused by plaque buildup and can occur in people who have high cholesterol such as Ms. T. Also, coronary spasms are known to cause angina pectoris in people (Taber’s pg 2171). Ms. T’s history of these conditions explains why she experiences episodes of angina. 4. The two predominant types of angina are…show more content…
Propranolol HcL drug to drug interactions: general anesthesia, IV phenytoin, and verapamil may cause additive myocardial depression. Additive bradycardia may occur with digoxin. Additive hypotension may occur with other antihypertensives, acute ingestion of alcohol, or nitrates. Levels may be decreased with chronic alcohol use. Concurrent use with amphetamines, cocaine, ephedrine, epinephrine, norepinephrine, phenylephrine, or pseudoephedrinemay result in unopposed alpha-adrenergic stimulation (excessive hypertension, bradycardia). Concurrent thyroid administration may decrease effectiveness. May alter the effectiveness of insulin or oral hypoglycemics(dose adjustments may be necessary). May decrease effectiveness of beta-adrenergic bronchodilatorsand theophylline. May decrease beneficial beta cardiovascular effects of dopamine or dobutamine. Use cautiously within 14 days of MAO inhibitor therapy (may result in hypertension). Cimetidine may increase blood levels and toxicity. Concurrent NSAIDs may decrease antihypertensive action. Smoking increases metabolism and decreases effects; smoking cessation may increase effects. May increase levels of lidocaine and bupivacaine. Nifedipine drug to drug interactions: Drug-Drug: Rifampin, rifabutin, phenobarbital, phenytoin, orcarbamazepine may significantly decrease levels and effects; concurrent use is contraindicated. Ketoconazole, fluconazole, itraconazole,clarithromycin,

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