A Brief Note On Colorectal Cancer And Cancer

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Colorectal cancer is one of the global leading diseases and it is the third most common causes of death in both men and women in America. Approximately 1 in 12 Australians will develop colorectal cancer in their lifetime, and according to Bowel Cancer Australia, individuals are at risk if they are aged 50 years and over, have had an inflammatory colorectal disease or significant family history of colorectal cancer polyps.

Although there are various treatments for colorectal cancer, complications may arise. Post-infection caused by surgical damage to the mucosa of the intestine may occur. Furthermore, a previous study indicated that although some chemotherapy regiment, such as FOLFOXIRI, can produce maximal response in decreasing tumour size at high dosage, it can also produce side effects such as neutropenia and diarrhoea because of the high toxicity level associated with the dosage of the drugs. As a result, it has become a necessity for researchers to trial new methods, such as combining drug regimen with surgery, to improve clinical outcomes from treatments in patients with colorectal cancer.

It has been raised in the media that gut microbiota in individuals can provide an indication of the development of colorectal cancer. Hence, using it as a screening method can allow early interventions to prevent colorectal carcinoma. Although the media mentions using gut microbiota analysis as a preventative screening method, it raises the question: What roles can gut bacteria

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