A Brief Note On Glucose And Its Effect On The Body

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

The American Diabetes Association (2004) defines diabetes as a subset of metabolic diseases associated with hyperglycemia secondary to insulin failing to release, act, or both. Complications related to chronic diabetes can be detrimental to one’s health including but not limited to: heart disease, stroke, kidney disease, amputations, blindness, and other optical diseases. Furthermore, the prevalence of diabetes is rising at an astronomical rate within the United States as well as internationally. According to the Center for Disease Control and Prevention (CDC) (2016) an estimated 29 million people suffer with diabetes and 86 million are prediabetic within the United States (US). Without major interventions from the healthcare community,

Uncontrolled diabetes can affect nearly every organ of the body; of which, heart disease and kidney failure are most commonly impacted. Known as diabetes mellitus, a collective term for various blood abnormalities, the term diabetes refers to either a scarcity of insulin in the body or the body’s inability to accept insulin. Though the symptoms of diabetes are manageable, many are unaware as to having it. According to the CDC report “2011 Diabetes Fact Sheet,” approximately 6 million people in the United States have undiagnosed diabetes. Undetected, diabetes can become deadly. In a recent World Health Organization report “Diabetes Action Now: An Initiative of the World Health Organization and the International Diabetes Federation,” it

Diabetes mellitus (DM) is a pandemic that affects millions of people. The growth rate of unrecognized pre-diabetes in America is expected to rise up to 52% by 2020 (Lorenzo, 2013). As the prevalence of diabetes increases, so will the complications and burden of the disease. One of the leading causes for cardiovascular disease, renal failure, nontraumatic lower limb amputations, stroke, and new cases of blindness is DM (Lorenzo, 2013).

Diabetes affects over 180 million people in the US and is projected that by 2025 this figure will increase to 300 million.

Diabetes mellitus (DM) is one of the main problems in health systems and a global public health threat that has increased dramatically over the past 2 decades (1, 2). According to epidemiological studies, the number of patients with DM increased from about 30 million cases in 1985, 177 million in 2000, 285 million in 2010, and estimated if the situation continues, more than 360 million people by 2030 will have DM (3, 4).

Diabetes type 2 is linked to a number of health complications including cardiovascular disease, kidney disease, depression, blindness and amputation. Up to 90% of patients suffering from diabetes type 2 is either overweight or obese, and this contributes to mentioned complications, that are thought to lower life expectancy in those patients. National Diabetes Audit XXX shows that there is a significantly higher change of suffering from a variety of cardiovascular diseases including myocardial infraction – 55% additional risk, stroke – 34% higher risk when compared to general population, angina and heart failure, 76 and 74% increased risk, respectively. Furthermore, people suffering from diabetes have 337% additional risk of minor amputation and 222% of major amputation when compared to general population. Risk of renal replacement therapy in diabetic patients is 164% higher than non-diabetic people. Despite the numbers, heart disease is still the most prevalent complication od type 2 diabetes in England and Wales. The risk of cardiovascular disease increases further for South-Asian diabetics and for people living in the most deprived and poorest areas, up to 50% more likely to suffer from cardiovascular disease when compared to least deprived diabetics. Patients suffering from diabetes type 2 and being obese are estimated to have a hospital admission due to heart failure twice as often as general population.

Diabetes is a major medical problem in the US. In the year 2015, it was reported that 86 million Americans are diagnosed with prediabetes (ADA, 2016). Diabetes is the seventh leading cause of death in the United States (CDC, 2016). Research has

Diabetes is associated with wide range of complications such as chronic renal failure, blindness, amputations, heart disease, high blood pressure, stroke, and neuropathy (Alotabi, A., et al., 2016). There is no known cure for diabetes, but the disease can be controlled through health management that includes multiple perspectives of care such as medications, blood glucose monitoring, diet, nutrition, screening for long-term complications and regular physical activity (Alotabi, A., et al., 2016). Managing diabetes may be complicated and requires the knowledge and skills of both healthcare providers and the clients. Studies have shown that to prevent or delay diabetic complications due to diabetes, counseling and other lifestyle interventions are the effective therapy. Even with many policies set up for diabetes, 8.1 million Americans are undiagnosed with diabetes mellitus, and approximately 86 million Americans ages 20 and older have blood glucose levels that considerably increase their risk of developing Diabetes Mellitus in the next several years (CDC, 2015). For diabetes care to be successful there needs to be a good understanding of the disease and management by both patients and healthcare providers,

Diabetes is the most rapidly growing incurable, chronic disease worldwide, which slowly but surely can kill those suffering from it. In Australia alone, the approximate effected population is expanding to over 1.7 million people and an estimated 3.3 million by 2031, with around 100 000 newly

Diabetes is a major problem in our society today. Many people have heard about the disease; however, they do not know too much about its complications. Diabetes is a chronic, progressive and lifelong condition that affects the body’s ability to use the energy found in food (WebMD, 2016). Many new cases are confirmed every year and unfortunately, many go undiagnosed for years. Diabetes is a serious disease and need to be taking seriously. The disease can lead to many other health problems such as blindness, nerve damage and kidney diseases. The more the community understand and made aware of the seriousness of the disease, the better it can be control and or prevented.

Diabetes is highly prevalent condition, affecting 8.2 % of adults globally or 382 million people. Incidence is increasing with a estimated global prevalence of 592 million people by 2035. It further results in Chronic kidney disease & further may lead to ESKD(End-Stage Kidney Disease).

Diabetes has been out for thousands of years and still no cure. researchers and scientist have been searching and searching for ways to overcome this disease but nothing yet. Everyone goals are to either improve, prevent, or cure this disease. Diabetes became very known around the seventeenth century because of a high percentage of people was found with sugar in their urine and blood. Diabetes is one of the fastest growing diseases that affects our society worldwide. The average person in this world does not know anything about this disease. The diabetes association said “In 2013 the estimate of 328 million people had diabetes throughout the world”. Society today need to be aware of what we are up against with this disease.

Homeostasis is what physiological systems in our bodies do in order to maintain a stable internal environment. Stability is held together by the coordinated responses of the components involved to any stress or unfamiliar situation that the human body is put under that could disrupt its normal functioning conditions. Homeostasis must be maintained constantly in order for our bodies to be able to function properly and not under stress which could have major effects later on in life.

Diabetes is a systemic disease caused by a decrease in the secretion of insulin or reduced sensitivity or responsiveness to insulin by target tissue. (Beale, et al., 2011) The incidence of diabetes is growing rapidly in the United States and worldwide. An estimated 347 million people around the world are afflicted with diabetes. (Whalen, et al., 2012) According to World Health Organization (WHO), Diabetes prevalence among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014. It is the major cause of blindness, kidney failure, heart attack, stroke and limbic amputation. World Health Organization (WHO) projects that diabetes will be the 7th leading cause of death in 2030. It is a complex and costly disease that can affect nearly every organ in the body and result in devastating consequences. The leading cause of non-traumatic lower extremity amputations, renal failure, and blindness in working-age adults, diabetes is also a major cause of premature mortality, stroke, cardiovascular disease, peripheral vascular disease, congenital malformations, perinatal mortality, and disability. (Cefalu, 2000) Insulin therapy and oral hypoglycemic agents have demonstrated improvement in glycaemic control. However, Insulin therapy has some disadvantages such as ineffectiveness following oral administration, short shelf life, of the need for constant refrigeration, and fatal hypoglycaemia, in the event of excess dosage.