A Cost-Effectiveness Analysis of Cognitive Behavior Therapy and Fluoxetine (Prozac) in the Treatment of Depression

9920 Words Jan 14th, 2011 40 Pages
BEHAVIORTHERAPY28, 187-210, 1997

A Cost-Effectiveness Analysis of Cognitive Behavior Therapy and Fluoxetine (Prozac) in the Treatment of Depression
DAVID O. ANTONUCCIO

University of Nevada School of Medicine and Reno V.A. Medical Center (116B2)
MICHAEL THOMAS

University of Nevada Dept. of Accounting and CIS

WILLIAM G. DANTON
University of Nevada School of Medicine and Reno EA. Medical Center/(116B2)
Depression affects at least 11 million Americans per year and costs the U.S. economy an estimated 44 billion dollars annually. Comprehensive review of the existing scientific evidence suggests that psychotherapy, particularly cognitive behavior therapy (CBT), is at least as effective as medication in the treatment of depression,
…show more content…
Clinical Outcome of CBT Compared With Pharmacotherapy
One approach to treating depression involves addressing the cognitions that mediate the emotional impact of events in patients ' lives (e.g., Beck, Rush, Shaw, & Emery, 1979; Beck & Young, 1985). The proponents of this approach assert that it is not necessarily aversive events that lead to depression, but rather cognitions about those events. CBT involves helping patients modify cognitive distortions that may be negatively impacting mood. Many studies have shown cognitive therapy to be more effective than antidepressant medication (Blackburn, Bishop, Glen, Whalley, & Christie, 1981; Evans et al., 1992; Kovacs, Rush, Beck, & Hollon, 1981; Rush, Beck, Kovacs, & Hollon, 1977; Rush, Beck, Kovacs, Weissenburger, & Hollon, 1982). Some studies have shown cognitive therapy alone to be as effective as antidepressant medication (Elkin et al., 1989; Hollon et al., 1992) or combined cognitive/drug treatment (Beck, Hollon, Young, Bedrosian, & Budenz, 1985; Blackburn et al., 1981; Covi & Lipman, 1987; Evans et al., 1992; Hollon et al. ; Murphy, Simons, Wetzel, & Lustman, 1984). Yet other studies suggest that cognitive therapy adds to the efficacy of standard antidepressant drug treatment (Bowers, 1990; Dunn, 1979; Miller, Norman, Keitner, Bishop, & Dow, 1989; Teasdale, Fennell, Hibbert, & Amies, 1984). Other studies have evaluated CBT treatments that emphasize the
Open Document