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The history of vaccinations begin with Edward Jenner, the country doctor from Gloucestershire who found, growing on cows, a nearly harmless virus the protected people from smallpox. Jenner’s vaccine was safer, more reliable, and more durable than variolation, and it is still the only vaccine to have eliminated its reason for being-in 1980, when the World Health Organization (WHO) declared the disease extinct. For nearly a century and a half, smallpox was the only vaccine routinely administered, and it saved millions of lives . But the controversy that marked the return of the vaccine, amid bioterrorism hysteria in 2002, was only the latest twist in the remarkable, mysterious life of vaccines.

As Ezekiel Emanuel, an American oncologist said, “Childhood vaccines are one of the great triumphs of modern medicine. Indeed, parents whose children are vaccinated no longer have to worry about their child’s death or disability from whooping cough, polio, diphtheria, hepatitis, or a host of other infections.” For millions of years diseases have plagued entire populations, and in the late 1700s, Edward Jenner invented the smallpox vaccination which brought about a new era of disease prevention. Vaccinations should be enforced because they save lives, rarely cause reactions, and have eliminated diseases.

Despite the disappearance of the plague, smallpox still ran rampant throughout the world. The terrible disease continued to kill millions of Europeans every year. An inoculation created in the early 1700s was a somewhat successful solution and thousands of Europeans underwent the operation to engraft their skin with smallpox (Doc 2). However, new, more efficient solution came in the form of Edward Jenner, who created the first smallpox vaccine by collecting cowpox from an infected person and inserting it into another individual’s arm (Doc 6). Edward Jenner’s new vaccine was virtually harmless and was the most efficient vaccination to date. The smallpox vaccine eradicated the disease in Europe and eventually, the entire world. Smallpox was the last great disease that Europeans faced and its elimination allowed Europe’s population to grow and

Edward Jenner invented a vaccine by using a naturally-acquired and mild cowpox to prevent smallpox. More than one thousand people were vaccinated in England alone within three years. The print media played an important role in spreading the word about these vaccinations and smallpox was finally eradicated in 1980 (Bouldin, 2010).

However, Jenner’s invention became a common practice only a few years after he released it to the public, and according to The Hutchinson Unabridged Encyclopedia, “By 1890 smallpox had virtually been eradicated from Britain.” (“Jenner, Edward (1749-1823)”) From the information about the first vaccination, we can see that vaccinations have been proven to eliminate deadly diseases, whether they receive opposition or not. Without immunizations, we would be overcome with diseases, such as smallpox, polio, and measles.

Mandatory vaccination continues to be a contentious subject in the United States, even though extensive evidence proves inoculation prevents certain diseases. According to A. Plotkin & L. Plotkin (2011), the evolution of the first vaccine commenced in the 1700’s when a physician named Edwards Jenner discovered that cowpox protected individuals from one of the deadliest diseases termed smallpox. The precise virus Jenner used is unclear; however, it was espoused in the extermination of smallpox worldwide. The researchers further explained, the unearthing of the subsequent vaccine known as chicken cholera occurred approximately 80 years later by Louise Pasteur. Ever since, copious vaccines such as rabies, yellow fever, varicella, pneumococcal, mumps and recently HPV have been introduced.

Jenner’s vaccine was so successful that the World Health Organization declared the word “entirely eradicated” of human smallpox on December 9, 1979 (Spier, 2015). As a consequence of this monumental success and other successes like it, people forget how deadly diseases like this can be and fail to attribute their lack of a crippling disease to vaccinations. Other diseases that have been considered eliminated in a similar manner to smallpox are: diphtheria, tetanus, pertussis, polio, measles, mumps, rubella, hepatitis A & B, yellow fever (Spier, 2015).

Since the early 1800’s vaccinations have been significant factors in eliminating many contagious diseases and, for the most part, have been an accepted part of preventative medicine in our nation. Veritably eradicating often fatal diseases such as smallpox, polio, and cholera, vaccinations have been vital in contributing to a healthier and more disease free world.

Although most people think Edward Jenner was the first person to attempt a vaccination, this is not true. The earliest vaccinations started in the 7th century when snake venom was drank by Buddhists to try to gain immunity from snakebites. In 1796, Edward Jenner, a doctor in England, discovered he could give people immunity to smallpox by injecting them with material from cowpox lesions. Smallpox was a significant disease in most countries and killed millions of people in Europe and Mexico. Steps had already been taken to eradicate smallpox but it was Jenner who discovered using cowpox to immunize against smallpox as being the safest method. Using smallpox to create the vaccine was not safe so Jenner’s idea helped to save many people. This was the beginning of developing vaccines to keep people safe from diseases that were capable of wiping out entire populations. This

For approximately three-thousand years, smallpox has ravaged and plagued the four corners of the globe. In fact, in the 17 th and 18 th centuries, it was claimed to be the most infectious disease in the West, with an astounding 90% mortality rate in America. It wasn't until 1796, with English surgeon Edward Jenner's smallpox vaccination, that the world saw relief from this devastating virus. However, even with this inoculation in use, the world continued to witness death from both the virus and the vaccine. In the year 1966, it was estimated that 10-15 million infected citizens world wide had passed away from smallpox that year alone ( “History” 12). As a result of these devastating numbers, in the following year, 1967, the World Health

The earliest case of smallpox according to a journal published in the US National Library of Medicine titled, “Edward Jenner and the History of Smallpox and Vaccination” was recorded as early as 1122 BC. (Riedel “Smallpox the Origin of a Disease”). Mankind’s triumph over this horrible disease was initiated by an English doctor named Edward Jenner. Through observations and experimentation, Jenner would create a procedure now known as vaccination. (Riedel “Edward Jenner”). During the next two centuries, vaccinations would be used worldwide to stop the spread of small pox. After the successful worldwide vaccination campaign led by the World Health Organization, small pox was eradicated worldwide in 1980. As a result of the eradication of smallpox according

Until the development of the smallpox vaccine in 1796, inoculation using the live smallpox virus was the only way to protect people from the deadly disease. Those inoculated had a chance of contracting the full virus and potentially dying from the disease. When Edward Jenner discovered that he could use a similar disease found in cattle, he began the modern era of vaccination (The College of Physicians of Philadelphia, 2015). Over the next 200 years, smallpox was essentially driven extinct by vaccination programs. Due to vaccines, a disease that killed an estimated 300 million people in the 20th century alone now only exists in a Center for Disease Control laboratory. (Flight, 2011).

First, in 1796, a doctor named Edward Jenner performed the very first vaccination. “Taking pus from a cowpox lesion on a milkmaid’s hand, Jenner inoculated an eight-year-old boy, James Phipps. Six weeks later Jenner variolated two sites on Phipps ' arm with smallpox, yet the boy was unaffected by this as well as subsequent exposures” (Minna & Markel, 2005)& (Cave, 2008). The first vaccination allowed people to recognize that it was beneficial for their health. It provided the base for the rest of the variations of vaccinations to come. Vaccinations began with the notion that it is rooted in the science of immunology. Throughout history, there have been many variations of this first vaccine for things such as small pox, mumps, malaria and guinea worm. (The College of Physicians of Philadelphia, n.d.)

Today most children in the United States live a much healthier life and parents live with much less anxiety due to vaccinations. More than 200 years ago, Edward Jenner conducted an experiment that would be one of the most astounding breakthroughs in medical history. Jenner noticed that milkmaids didn’t catch the smallpox, a disease rampant across the English countryside. He reasoned that the blisters on the milkmaid’s hand must contain something that was protective. He tested his theory by taking fluid from a blister on the wrist of a milkmaid and inoculating it into the arm of a local laborer’s son (Offit and

According to my research, in 1796 Dr. Edward Jenner developed a vaccine for smallpox disease however during this time only cows were infected. This vaccine came from the cowpox virus. In 1809, the state of Massachusetts became the first to mandate the smallpox vaccinations then in 1879 a group of Anti-Vaccination of America was formed and their belief is that no one should be forced to vaccination. They believed that the vaccine was spreading the disease instead of preventing it. In 1986