A Genetic Engineering Outline

598 Words2 Pages
o TH Morgan concluded that chromosome play an important part in heredity and the passing on genetic traits o Griffith injected mice with different types of bacteria and when he injected them with S cells, the mice died. When the mice were injected with the R cells, they continued to live. The mice would survive if they were injected with heat-killed S Cells but died when given a dosage of heat-killed S Cells and normal R Cells. The reaction of the two cells was the possible and most likely death of the mouse. o Avery, Macleod, and McCarthy took the findings of Griffith and wanted to reason why the combination of the two cells killed the mouse. The took the different parts which would cause the DNA, Protein, and RNA and eventually eliminated them one by one. After all of that, only bacteria that was exposed to the S-strain DNA were transformed. This gave the idea that DNA is what was controlling living things and was the outcome of this experiment o Hershey and Chase Radioactively tagged and then tracked infected bacteria in order to prove that DNA was in fact the molecule of heredity and transferring of genetic material o Chargaff proved two very important rules about DNA, • All species have different amounts of adenine, thymine, cytosine and guanine in their DNA • The Amount of Adenine, Cytosine, Guanine and Thymine in each species’ DNA is different. o Crick and Watson used X-ray diffraction data, which Rosalind Franklin developed which was then used to develop the ‘double
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