A Genetic Review Of Schizophreni Research Progress Of Chromosomes 22 And 8

3307 Words Nov 30th, 2014 14 Pages
December 1, 2014

A Genetic Review of Schizophrenia: Research progress of chromosomes 22 and 8

Present to: Geraldine Boyden
By: Quiana Jones

Core Articles:

Gill M, Vallada H, Collier D et al: A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Am J Med Genet Neuropsychiatr Genet 1996; 67: 40–45.

Polymeropoulos MH, Coon H, Byerley W, et al: Search for schizophrenia susceptibility locus on human chromosome 22. Am J Med Genet 54:93-99, 1994

Pulver AE, Karayiorgou M, Wolyniec PS et al: Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome 22q12–q13.1: Part 1. Am J Med Genet 1994; 54: 36–43.

Stefansson H, Sigurdsson E, Steinthorsdottir V et al: Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet 2002; 71: 877–892.

Yin, Dong-Min et al. “Reversal of Behavioral Deficits and Synaptic Dysfunction in Mice Overexpressing Neuregulin 1.” Neuron 78.4 (2013): 644–657. PMC. Web. 1 Dec. 2014.

Quiana Jones
Schizophrenia Article Review

I. Introduction
Schizophrenia is a crippling mental disorder that is characterized by a patient’s inability to decide what is real. Affecting about 1% of the population, schizophrenia is evenly distributed among men and women (Schizophrenia). Men tend to develop symptoms earlier than women. Symptoms usually appear between the ages of 16 and 30 and, for the most part, do not…
Open Document