A Multistep Recruitment Strategy to a Participant-Intensive Clinical Trial

To start out, it is important to differentiate between practice and research, especially in this discussion of therapeutic research trials. Practice is meant to treat an individual in order to improve upon their quality of life. The practice of medicine generally yields good outcomes and is not inherently risky, with some exceptions. However, research on the other hand includes subjects or participants to learn something about people or a topic as a whole. While it seems that the differences are clear, there are many times when the lines between the two may blur. One of the ways that the differences are more ambiguous is in the case of

The title does identify the general idea of the study but it could be more informational. The authors are Kari Sand-Jecklin, EdD, MSN, RN, AHN-BC, Associate Professor of Nursing, West Virginia University, Morgantown, WV. Jay Sherman, CNRN, ME, Clinical Research Nurse, West Virginia University Healthcare, Morgantown, WV. The information provided does qualify both authors to study the topic. The abstract is

A Paper Submitted in partial fulfillment of the requirements for NU 533 Advanced Nursing Research University of South Alabama College of Nursing Spring 2011

Evidence-based nursing practice is a result of research studies or randomized controlled trials (RCT). However, from these trials, a compilation of the evidence is gathered that determines the direction of future trials. Often, the results or findings of the research article will indicate if further studies are warranted and indicated why these studies would be beneficial. Also, the possibility of any sampling error, or selection bias that may have of skewed results of the RCT. Wong and Myers (2015) place the responsibility in the hands of the managers, educators, and clinical nurse specialists to stay abreast of recommended changes, educate and evaluate their clinicians(p. 18). However, the weight of their due diligence begins with gaining

Christensen, B.L., Kockrow, E.O., Cooper, K., Gosnell, K. and MS.., B.L.C. (2014) Foundations of nursing. 6th edn. United States: Elsevier Health Sciences.

(HF) patients. The scientific basis of this clinical trial is the Chronic Care Model, which emphasizes engaging patients in self-management partnerships with multiple professionals. (Smith et al., 2015, p. S25-26)

This paper is being submitted on August 11, 2017 for Virginia Aulik’s Professional Nursing course.

Patient recruitment is one of the biggest obstacles, and challenges, in clinical research, and a major cause of delays in developing promising new treatments. Nearly 30% of the time spent in clinical trials is dedicated to patient recruitment and enrollment, making it the most time intensive of all tasks.

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ClinicalTrials.gov is designed to benefit community of clinical researchers by expanding access to clinical trial data. Clinical trial registry launched by clinicaltrials.gov, has data for more than 100,000 clinical studies and has promoted the state of clinical research. As per the instructions of ClinicalTrials.gov, data providers have to specify outcome measures and timeframe of the clinical trials. This has helped a growing number of clinical researchers to conduct a several primary and secondary analyses. The contribution of publicly available clinical trial data will continue to make significant impact on clinical research enterprise [1].

Eligible participants will be divided in two groups of 75 participants, which will be assigned as group A and B. A computer randomization program will generate Group A, which will be identified as patient currently on pharmacological intervention for cardiovascular diseases and Group B will be participant status post MI.

The participants were relevant to the research questions. The sample consisted of RN’s with at least 1 year of clinical experience and no clinical practice within the previous 6 months. Nurses with additional years of

Possible risks and side effects of participating in the study. Volunteers must be informed of previously recorded adverse effects of engaging in the study.

Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc.

According to pre-experiment planning, 700 patients would be necessary to provide sufficient statistical power to address the hypothesis. The authors drew study participants from 22 medical centers in Australia and New Zealand. Given the nature of the inclusion criteria, a multicenter approach was needed to recruit such a large number. In the end, they did not recruit a buffer to allow for drop-outs and this cost them their statistical power. This was not appropriately planned.