A Research Study : Fife Are Retrospective And One Prospective Study

1821 Words Jun 18th, 2015 8 Pages
Six studies conducted in the USA , fife are retrospective and one prospective study , the first study was set in Three large Tertiary care center and the sample size was795 patients. Used list of triggers like (medication stop order, an abnormal lab result, or use of an antidote medication).
Second study was set in Bon Secor, Atlantic Health, Cleveland Clinic, and the University of Kentucky the sample size was 86 hospitals reviewed 2837 charts.Used list of triggers like(Diphenhydramine , Vitamin K , Flumazenil , Droperidol , Naloxone , Antidiarrheals , Sodium polystyrene , PTT >100 seconds , INR >6 , Serum glucose < 70 mg/dL, INR > 4.5, K+ ≥ 5.5 mmol/L, K+ ≤3.5 mmol/L, Platelets < 75,000/mm3,, aPTT > 100, ALT/AST ≥3x ULN, Na+ < 130 mmol/L, ALP >121 IU/L) the result Among 321 Veterans, 50.5% (n=162) had at least one abnormal laboratory value contained in the trigger tool. Ninety-nine potential ADEs involving 146 medications were detected in 65 Veterans. The overall PPV of the ADE trigger tool was 40.1% (65/162), and the average time to complete resident assessments was 8.8 (sd ± 5.7) minutes. The most common potential ADEs were acute kidney injury (n=30 residents), hypokalemia (n=18), hypoglycemia (n=13), and hyperkalemia (n=10).
There are several potential limitations that deserve mention. First, the cross-sectional design limits our ability to assess ADEs that may more commonly occur during other times of the year in the NH setting. Moreover, this was a…
Open Document