A Short Note On Cardiomyopathy And Humans And Canines

1121 WordsApr 20, 20175 Pages
Dilated Cardiomyopathy in Canines & Humans BIOL-312 Term Paper Mycah Baker History Cardiovascular disease is one of the leading causes of death in both humans and canines. Cardiomyopathy is a disease in which the heart muscles become enlarged, inflexible, and dense. Dilated Cardiomyopathy (DCM) is a specific type of Cardiomyopathy in which only the muscles in the ventricles of the heart become enlarged and weakened. DCM normally begins in the left ventricle, but it can spread to the right ventricle as well; at that point, the heart works harder and thus cannot efficiently pump blood [3]. DCM is the third most common type of cardiac disease in humans and the second most common type of cardiac disease in canines [2]. The term…show more content…
DCM is also believed to be mainly inherited in humans in an autosomal dominant manner [2]. A pathology examination of canines with DCM generally shows prevalent dilatation of the left chambers of the heart or even dilatation of all four cardiac chambers [1]. Ventricular hypertrophy is evident in both humans and canines due to the presence of an increased heart weight/body weight ratio, as well as a decreased ratio of left ventricular wall thickness to chamber diameter [1]. Diagnosis Some individuals who have dilated cardiomyopathy do not show symptoms in the beginning stages [3]. During this period, there is no functional changes in cardiac tissue showing, but it is probable that the main cause such as genetic factors, toxins, and infections is already introducing the disease [2]. During the next stage, there may not be any outward symptoms noticed and the individual may appear to be healthy, but cardiovascular electrical and morphological changes can usually be detected [2]. The final stage of DCM includes the clinical signs of heart failure, such as: dyspnea (shortness of breath), fatigue, edema, dizziness, syncope (fainting), arrhythmias, chest pain, and heart murmurs [3]. The main diagnostic tests used to detect DCM in both canines and humans include: echocardiograph, biopsy, electrocardiogram, and blood tests [1,3]. Symptoms of DCM in canines usually include: cough, depression,

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