A Short Note On Diabetes And Heart Failure

1811 Words Nov 8th, 2016 8 Pages
 -blockers in heart failure

Increased sympathetic activity has the ability to cause ventricular dysrhythmias following myocardial infarction [1]. -blockers as a class of drugs are competitive antagonists which block the receptor sites of the endogenous hormones of the sympathetic nervous system: adrenaline and noradrenaline, which can cause dysrhythmias.
Heart failure (HF) is failure of the heart muscle to sufficiently provide oxygenated blood to the organs of the body. This is a disease of the cardiac muscle. This causes a reduction in the volume of blood the heart pumps and hence not enough blood to circulate and return to the heart and lungs. This then results in the leakage of fluid, mainly water, from the capillary blood vessels which are responsible for the common symptoms of heart failure; fatigue, shortness of breath and swelling [2]. Chronic Heart Failure (CHF) is a common clinical syndrome caused by Coronary Artery Diseases (CAD), hypertension, valvular heart disease, and/or primary cardiomyopathy [3]. Ischemic Heart Disease (IHD) is mainly reduction of blood flow in the coronary arteries to supply the heart with oxygen and nutrients due to narrowing of the coronary arteries normally due to the build up of fat deposits in the blood vessel (atheroma).

Left ventricular dysfunction is often as a result of a myocardial infarction (acute) or hypertension (chronic) and this causes an upscale of the activities of the sympathetic…
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