Lymphoma, a cancer that starts in white blood cells called lymphocytes, is the most common blood cancer. Hodgkin lymphoma is one of two common types of lymphoma that considered to be one of the most curable forms of cancer. This research paper is going to introduce Hodgkin Lymphoma in several aspects in order to give an overview of the cancer.
What is the type of the cancer?
Hodgkin lymphoma is a cancer of the lymphatic system, which is part of human body’s immune system (Mayo Clinic, 2014).
It usually starts in a lymph node. The disease begins when a lymphocyte becomes abnormal. The abnormal cell makes copies of itself by keeping dividing. The lymph node that contains abnormal cells becomes swollen when the abnormal cells
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What is the cause of the cancer?
The cause of Hodgkin lymphoma is not clear. The most Hodgkin lymphoma occurs when an infection-fighting cell called a B cell develops a DNA mutation. The cells then divide very fast, causing a large number of abnormal B cells to accumulate in the lymphatic system, where they crowd out healthy cells (Mayo Clinic, 2014).
How to prevent the cancer?
The exact cause of Hodgkin lymphoma is not yet known, so there are no known changes to prevent most cases of the disease at this time.
The only way to limit the risk would be to avoid known risk factors (American Cancer Society, 2015).
How to diagnose the cancer?
Mayo Clinic’s (2014) study found the following:
Tests and procedures used to diagnose Hodgkin 's lymphoma include physical exam, blood tests, imaging tests, surgery to remove a swollen lymph node and a procedure to collect bone marrow for testing.
Physical exam checks for swollen lymph nodes, including in neck, underarm and groin, as well as a swollen spleen or liver.
Blood tests examines a sample of patient’s blood in a lab to see if anything in blood indicates the possibility of cancer. Imaging tests used to diagnose Hodgkin 's lymphoma include X-ray, computerized
tomography (CT) scan and positron emission tomography (PET). Minor surgery may be done to remove all or part of an
Lymphoma is the name given to a cancer that infects the lymphatic system. In a case of lymphoma the lymphatic system has cells that multiply and cannot be stopped. There are two main types of lymphoma, Hodgkin’s and non-Hodgkin’s. Non-Hodgkin’s lymphoma is called
The diagnosis of multiple myeloma can occur after a routine blood test with your doctor. However, the most common diagnosis occurs when doctors take an x-ray of a broken bone and suspect the cancer has caused or is a contributing factor to the broken bone. When analyzing the blood tests, the following are considered when diagnosing multiple myeloma: people with multiple myeloma have high levels of proteins in the blood, especially M and other immunoglobulin, albumin, and beta-2-microglobulin. Also, the blood exam tests for high levels of calcium and for creatinine levels (to assure that the kidneys are working properly).3 Other ways to test for multiple myeloma include urine tests, x-rays, biopsies (test the bone marrow itself from a large bone - a painful procedure). Unfortunately, Multiple myeloma is a very fatal cancer, where only 35% of patients diagnosed with multiple myeloma living 5 years past their diagnosis.3
Thesis Statement: Hodgkin’s Lymphoma, although rare, can be fatal and it is important to be informed on the cause, symptoms, and treatments to further your awareness and provide a better understanding on the dynamics of this disease.
Tests to see if you have other types of tumors in other parts of the body.
Although research opinions vary on the cause of lymphomas, it is known that T-cell lymphomas are very rare. Lymphomas are thought to be caused by the damaged genes that control the development of the body’s blood cells ( B and T Cell Lymphomas, n.d.) The B- cells and T-cells play different roles in the body. T-cells can be helper cells, suppressor cells or killer cells (Story, 2012). It is the
There are at least 30 different entities referred to as non-Hodgkin's lymphomas, and they range from the indolent to the very aggressive. Taken together, the non-Hodgkin's lymphomas are the fifth most common cancers in the United States and the fifth leading cause of death due to cancer 1. More than 356,000 cases are diagnosed annually with Non-Hodgkin lymphoma (NHL), however, mortality cases are high as well, evaluated as 192,000 2. NHL is defined as a combination of malignancies originating from T- and B-lymphocytes in the lymph nodes 3, 4. The invasion is not only restricted to the lymphatic system but the central nervous system, the skin, the bone marrow and adrenal glands are commonly affected as well 5, 6. Numerous factors are associated with the progression of NHL as organs
To break it down into types of Hodgkin’s, there is the classical and the rare. The classical Hodgkin’s Lymphoma’s abnormal cells are called Reed-Sternberg cells. In this type thousands of people are diagnosed every year. In the rare type, which is called lymphocyte-predominant
Cancer is defined as the disease caused by an uncontrollable division of abnormal cells in a part of the body. The particular cancer that I️ researched is Non-Hodgkin Lymphoma (NHL) which is a type of cancer that begins in the cells of the lymph system. (Lymphoma) The lymph system is a part of the immune system. Lymph tissue is found all throughout the body; therefore, Lymphoma can begin from almost any part of the body since the major sites of lymph tissue are the lymph nodes, spleen, bone marrow, thymus, digestive tract, and adenoids and tonsils. (What) “In most cases, it is not known what causes Non-Hodgkin Lymphoma.” (Risk) Some risk factors of NHL are beyond our control such as age and gender but usually they are acquired rather than inherited. (Risk) NHL begins in white blood cells called lymphocytes. (What) There are two main types of lymphocytes: B lymphocytes ( B cells) and T lymphocytes (T cells). B cells normally create antibodies to
These tests will let him know if he has any developments in his body that is cancerous. If ever the illness is still in the early stages, he can go to experts immediately so that he can undergo the necessary treatment to remove these cells in his body and give him a high chance of surviving the deadly illness.
Hodgkin’s Lymphoma can occur in children, teens, and adults. It is more common in early adult hood between the ages of 15 to 40, and especially in people in their 20’s Hodgkin’s Lymphoma the nodular sclerosis subtype, is most common in late adulthood after the age of 55. Hodgkin’s Lymphoma is rare in children younger than the age of 5, but about 10% to 15% of cases are diagnosed in children and
Non-Hodgkin lymphoma and Hodgkin lymphoma are cancers that start in the lymph tissues, such as the tonsils, lymph nodes, and thymus. These cancers may spread to bone marrow and other organs, which can cause different symptoms depending on where it is growing. Hodgkin’s lymphoma can occur in both children and adults, and accounts for about 4% of childhood cancers. It is more common, though, in two age groups: early adulthood (age 15-40, usually people in their 20s) and late adulthood (after 55). Hodgkin lymphoma is rare in children younger than five years of age. About 10% to 15% of cases are diagnosed in children and teenagers. About 81 out of 100 people diagnosed with non-Hodgkin’s lymphoma are alive one year after the disease is diagnosed. About 63 out of 100 people with the disease are alive at five years, and 49 out of 100 at 10 years (Non-Hodgkin’s Lymphoma, 2005-2010).
Because Hodgkin’s disease is associated with a defect in the maturation of the lymphocyte, the immune system may be impaired. As such repeated infections may occur.
CLL is diagnosed with a physical exam, including a complete history, and blood & bone marrow tests. Many types of blood and bone marrow tests can be performed including:
There are two main and four specific types of leukemia. The two main types are acute leukemia, which is fast growing, and chronic leukemia, which is slow growing. The four specific types of leukemia are chronic lymphocytic (CLL), acute lymphocytic (ALL), chronic myelogenous (CML), and acute myelogenous (AML) that were discovered in 1913. About three quarters of children diagnosed with leukemia have acute lymphocytic which peaks as early as two to four years old. This cancer kills more children that are two or fifteen than anything else. To determine whether the cancer will be chronic or acute is to look at the cell lineage. The blood cell that becomes cancerous explains what type of leukemia it is. Depending on if the white cells, the red blood cells, or the platelets can determine exactly which leukemia it is. “Adults can get either type; children with leukemia most often have an acute type” (Leukemia: MedlinePlus). For a child to get a chronic leukemia is very rare. Now it is known that the cancer starts in the bone marrow, which is where blood cells are formed. Leukemia causes the body to create too many abnormal cells and these abnormal white cells cannot fight infection and also lessen the amount of red cells and platelets. Some of the risk factors of this cancer are large doses of ionizing radiation, being exposed to benzene for a long period of time, rare viruses, genetic disorders, and
When diagnosing bone cancer, a doctor must first complete some tests. According to a summary of tests and procedures by Medicine Net on line, a doctor will first ask about a patient’s personal and family medical history in order to find out if there is any history of cancer in the family. Next, the doctor will order blood tests and x-rays. The exact size, shape, and location of a bone tumor can be seen through an x-ray. Then, a CAT scan (Computed Axial Tomography) will be completed to show whether the cancer has begun to spread to other parts of the body. A CAT scan will give detailed pictures of the cross section of the body. There are also similar tests like an MRI (Magnetic Resonance Imaging) and an Angiogram (x-ray of the arteries), but a biopsy is the ultimate test that will make sure that cancer is present in the body. After the victim was told that she had bone cancer, she experienced a biopsy in Seattle, Washington. The Medicine Net on line explained that during a biopsy, doctors test a sample of the bone tumor and determine through a microscope whether or not the tumor is cancerous. The many different tests of bone cancer are very critical to the outcome of the disease. The tests are used for staging the bone cancer. For example, if a patient of bone cancer had a CAT scan, and it showed that the bone cancer was not spreading, the doctors could stage the patient’s cancer as controlled.