A Short Note On The Problem Associated With Peripheral Arterial Disease ( Pad ) Patients

1516 WordsFeb 1, 20167 Pages
Project title - Study on Polypharmacy in patients with Peripheral Arterial disease. The aim of the current study is to examine the problems associated with polypharmacy in peripheral arterial disease (PAD) patients. The primary objective of this study is to analyze: 1. Prevalence of polypharmacy in PAD patients 2. Major drug classes contributing to polypharmacy in patients with PAD. 3. The association of polypharmacy with events a) Progression of PAD b) Open surgical revascularization c) Amputation d) Cardiovascular events i) Myocardial infarction ii) Coronary heart disease iii) Stroke iv) Heart failure e) Renal disease f) Framingham 10 year CVD risk score g) Death The secondary objective of this study is to analyze the effect of polypharmacy on the following outcomes in PAD patients 1. Inappropriate prescribing using Indicators 2. Adverse drug events 3. Potential drug interactions 4. Healthcare costs 5. Nutrition 6. Cognitive function 7. Functional status 8. Frailty 9. Medication adherence 10. Quality of life Background Increasing age and related comorbidities have resulted in excessive use of drugs causing increased incidence of adverse effects, inappropriate medication use and increased health care costs1. Polypharmacy has become a significant problem in caring patients. A 10 year old study in finland from 1980 to 1990s showed that the use of polypharmacy increased more than three times2. Major polypharmacy (>5 drugs) prevalence in south wales and Netherlands

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