A Study On Diabetes Mellitus

Type II Diabetes, also known as diabetes mellitus, is also called non-insulin-dependent diabetes or aadult onset diabetes. It is a medical disorder that, due to a number of factors codependent with the modern world, is characterized by higher than normal blood glucose levels that play havoc with insulin deficiency and resistance. Insulin resistance means that cells do not respond appropriately when there is free insulin in the blood system. Essentially, they body is reacting to an improper balance of sugars and insulin. Because obesity is often present, research suggests that even thought the mechanisms controling glucose and insulin are unclear, the adopose tissue likely

The increase in the prevalence of type 2 diabetes is causing huge health problem through out the world including developed countries. Mostly people with low income groups are affected in developed countries (Zimmet 2001).The magnitude of the healthcare problem of type 2 diabetes results mainly from its association with obesity and cardiovascular risk factors. Indeed, type 2 diabetes has now been identified as one manifestation of the “metabolic syndrome”, a condition characterised by insulin resistance and associated with a range of cardiovascular factors (Jonathan 2003)

     Diabetes mellitus is a group of metabolic disorders characterized by inadequate insulin secretion by the pancreas or cellular destruction leading to an insulin deficiency. Depending on the cause of the insulin shortage, diabetes can be subcategorized into type I and type II. Type I diabetes (T1DM) is usually mediated by the destruction of b-cells in the pancreas resulting in decreased insulin production and secretion. Type II diabetes (T2DM) is the failure of these b-cells to secrete adequate amounts of insulin to compensate for insulin resistance and increased gluconeogenesis combined with an overall resistance to the insulin action (8., 1997). T2DM accounts

Type-II diabetes mellitus (also referred to as simply type-II diabetes or T2DM) is a chronic disease in which individuals are unable to produce adequate amounts of insulin from the pancreas, or who are unable to use any

In type 2 diabetes (formerly called non-insulin-dependent diabetes or adult-onset diabetes), the pancreas continues to produce insulin, sometimes even at higher-than-normal levels. However, the body develops resistance to the effects of insulin, so

Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects in the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy. This converted glucose needs to enter our cells so that it can be used for energy and growth. And in order for the glucose to enter our cells, there needs to be insulin present, which the beta cells of the pancreas is responsible for producing. This hormone is responsible for maintaining glucose level in the blood. It allows the body cells to use glucose as a main

A “diabetogenic lifestyle” paired with a “susceptible genotype” results in this Diabetes Mellitus, Type II. This condition is complex and is accompanied by deeper functional changes; which can be explained through the translation of Romesh Khardori, MD, PhD, FACP definition of the pathophysiology of Diabetes Mellitus, Type II. Type II diabetes is a grouping of two different components. The first component being peripheral insulin resistance; and the second being insufficient insulin secretion by pancreatic beta cells (Khardori, Romesh, MD, PhD, FACP). An example of this combination helps further explain. Being overweight and eating unhealthy—a “diabetogenic lifestyle”—results in insulin resistance; however, in order for diabetes to occur, the overweight individual’s body must be lacking the ability to increase insulin secretion enough to counteract for the insulin resistance (Khardori, Romesh, MD, PhD, FACP).

Type 2 Diabetes mellitus: This is characterized by the failure of the body cells to respond to the insulin produced. It is non-insulin dependent diabetes mellitus because although the pancreas still produces insulin, the body cells have somehow developed an insulin resistance (WHO, 2011).

Type 2 diabetes is a very well known disease throughout the US. There are about 27 million people in the US with the disease and 86 million others have prediabetes which means their blood glucose is not right but also not high enough to be diabetes yet. 208,000 people under the age of twenty have been diagnosed with either Type 1 or 2 Diabetes.

As we all know diabetes is a very well-known health disorder known around the world. Diabetes is a disorder of metabolism in which the body’s inability to produce any or enough insulin causes elevated levels of glucose in the blood. An estimated 23.6 million people in the United States have diabetes, a serious, lifelong condition. Half of the diabetic population have been diagnosed with this specific condition while others have not. Every year, about 1.6 million people aged 20 or older are diagnosed with diabetes. Furthermore, our bodies use digested food for growth and energy so our bodies can maintain a steady metabolism. Most of the food we eat is broken down into glucose, which is a form of sugar in the blood. Glucose is the main

This is also known as (NIDDM) or “adult-onset diabetes”. The primary cause for this condition is excess body weight and a lack of exercising.

Diabetes mellitus is usually a lifelong metabolic disorder characterized by hyperglycemia or high sugar levels in the blood; can be caused by lack of insulin, insulin resistance, or both. Insulin is a hormone produced by the pancreas to regulate blood sugar. It controls the metabolism of carbohydrates and fats that the body used for energy. Without insulin, glucose (sugar) in the blood builds up causing hyperglycemia. There are 3 classic symptoms of diabetes; the 3 Ps: polyuria which defines as frequent and excessive urination, polydipsia which defines as excessive thirst, and polyphagia which defines as excessive eating.

Diabetes Mellitus (DM) is a metabolic disorder resulting in hyperglycemia (high blood glucose level), and its characteristic signs and symptoms are polydipsia, polyphagia, and polyuria. In most cases, the contributory factors include pancreatic disorder or destruction of the beta cells of the Langerhans affecting insulin production. However, globally 592 million people are expected to be diagnosed with DM by 2035 which is about 53% increase (Bone, 2015). Actually, the four different types of DM are Type 1 DM (formally known as insulin dependent), Type 2 DM (formally known as non-insulin dependent), gestational diabetes mellitus (GDM), and secondary DM caused by hormonal abnormalities and pancreatic diseases (Arcangelo & Peterson, 2013). Proper management of the diabetes include early detection, understanding the signs and symptoms and treat the patient accordingly to control the blood glucose level, since there is no cure for the disease. In addition, complications such as amputation and organ damage are prevented, as well as preventing untimely death.

Diabetes is chronic long term group of health condition with high level of blood sugar which can lead to serious health consequences. Basically diabetes is a disorder of glucose metabolism. Insulin is a hormone that plays major role in glucose metabolism. Food contains carbohydrates which metabolize into glucose and with help of insulin glucose enters into cells. There are two main types of diabetes. When an individual’s body is unable to make enough insulin or body is unable to use its own insulin leads to high glucose level which is called diabetes type 2 or adult onset diabetes. Type 1 diabetes is juvenile onset diabetes caused by destruction of beta cell in pancreas ultimately there is no more production of insulin. High blood sugar level during pregnancy is called gestational diabetes which will disappear after pregnancy. People with diabetes might have following of sign and symptoms: increase in thirst, urination, hunger, decrease in vision and weight, tingling in extremities as well as dry skin. Diabetes is a leading cause of number of co-morbid conditions. Atherosclerosis is a micro vascular disease and is one of major cause of myocardial infarction, brain stroke, impotence in men as well as amputation of limbs. Diabetic retinopathy is causes blindness. Diabetes is a silent disorder so annual checkup of vision required and patient should be educated to report to the doctor if there is any vision change. Other co-morbid conditions are: obesity, depression, anxiety,

The common sort of diabetes disease is Diabetes mellitus type 2 (T2DM) that covers the 90% diabetic cases. It is a metabolic disorder that is determined by hyperglycemia (high level of blood sugar) as a result of resistance to insulin in cell membrane and relative lack of insulin [2, 10]. Type 2 diabetes is a