A Wide Range Of Therapeutic Applications Against Various Diseases

For many years, Africa had used herbs to cure various ailments such as AIDS. Because of the lack of treatments available, doctors have been prescribing certain herbs, such as hypoxis. (Mills) Although it doesn’t provide a cure, it does help with the lack of immune system due to the disease. Although there haven’t been any official clinical trials on the drug, there appears to have negligible side effects compared to other medicines typically proscribed for this disease. Another plant that is often prescribed is Sutherlandia. Although it treats AIDS, it is prescribed for many other diseases such as depression. Unlike hypoxis, it has gone through clinical trials, although there are still relatively few (Mills).

The Autumn Crocus, also known as meadow saffron, is not threatened and is sold as an ornamental plant since it has been cultivated in much of the world (Akram 2012). Although colchicine is typically used for treatment of gout and rheumatic complaints, there has been renewed interest in this medicine by many natural product researchers (Heran 2011). Further research of colchicine derived from the Autumn Crocus as a cancer fighting drug should be conducted due to ability to block cell

Natural products used to treat many diseases for a long time. Natural products derived from many sources such as fungus like Piptoporus betulinus, which is used as an antiseptic and disinfectant and plants like Alhagi maurorum, which is used to treat anorexia, constipation, dermatosis, epistaxis, fever, leprosy, and obesity. (1) In this research, we will focus on one natural product derived from a plant called Serenoa repens. Serenoa repens also called Saw palmetto, is a plant grows up to 1m in width and 3m in height. Each part of it has different uses, for example, its leaves are used to make thatching, baskets, fans, brushes, brooms, rope, fire kindling, fish traps and dolls and its berries are used as food and as medicine. There are many

In the United States, many diseases like the flu are treated easily by available drugs administered by pharmacies. However, in third world countries like Africa, medical supply is not affordable in environments festered with contaminated water supply and lack of food sources. Sub-Saharan Africa is plagued by many diseases, but the most common disease is Malaria. Malaria is a type of disease that is spread by the female mosquito of the genus Anopheles. An individual will start to experience high fevers and chills. If left untreated, the individual could possibly die (Heyneman, 2014). Antimalarial drugs are a type of treatment that can counteract this disease. Doxycycline is an antimalarial drug that is commonly used, however its

Traditionally, the root of A. racemosus has been widely used to increase fertility and libido, cures inflammation of sexual organs, enhances ovulation, prepares the womb for conception and prevents miscarriages (Kalia et al., 2003; Naik, 1988; Dwivedi & Tewari, 1991). Although, A. racemosus roots also known to possess estrogenic property (Tewari et al., 1968), but it has also been documented that at higher doses of A. racemosus, it maintains the balance between the endogenous female sex hormones (Sharma and Bhatnagar, 2011). Moreover, the ethno medical use of A. racemosus root as an anticonvulsant has been experimentally validated in our laboratory (unpublished data) as well as by other researchers too (references). The available literature reveals that the plant has not been explored with respect to its therapeutic potential as an anticonvulsant in catamenial epilepsy. But nowadays the virtual screening of the phytochemicals is believed to be a major tool for drug discovery beyond their ethnic use. Hence, an effort has been made to explore the pharmacological activities of Asparagus racemosus root using Prediction of Activity Spectra for Substances (PASS) and Pharmaexpert. In line with in our current study, a PASS based analysis (Table 1 & 2) revealed the presence of different bioactive phytoconstituents which might be responsible as an anticonvulsant with the most significant possibility of getting effective in the management of catamenial

The main purpose of the study is to determine the inhibitory effect of Daucus carota subsp. sativus on Wistar rats and its future

They have been reported to possess antioxidant,1-4 antimalarial,5 antileishmanial,6 antiinflammatory,7 antitumor8 and antibacterial activity9. The presence of a reactive

Elafin is an anti-inflammatory peptide which specifically inhibits neutrophil elastase and proteinase-3 that would otherwise result in excessive inflammation and tissue damage. It has 57 amino acid residues and two functional domains; the C-terminus which is a globular whey acid protein (WAP) and the N-terminus which binds to transglutaminase enzyme. Its structure is characterised by a planar spiral shape with an exposed external loop connected by four disulphides to the internal B-sheath

Available treatment options for diseases are limited by our knowledge. At the local hospice center, where I volunteered 2 years, these limitations were evident. The majority of my clients were disadvantaged due to a lack of treatment options. The limitations I saw firsthand instigated my pursual of research to explore an in depth relationship between disease and host.

Of all the diseases mentioned above, malaria presents a threat to the greatest number of people. It is a health problem today in more that 90 countries, with total populations of more than 2,400 million people--about 40% of the world's population. It is estimated that there are up to 500 million cases a year worldwide (Glaxo). A British pharmaceutical company called Glaxo Wellcome recently developed the first new industrially researched malaria remedy since World War II. It is a combination drug containing 2 substances, atovaquone and proguanil, given the commercial name Malarone. While this product has proven to be extremely effective in cases involving drug-resistant strains of malaria, the atovaquone component is very expensive to produce, and each recipient requires a full round of therapy lest a Malarone-resistant strain of malaria develop (Glaxo). Most of the people who need Malarone have no access to consistent health care, and cannot afford to pay for the medicine. With this in mind, Glaxo Wellcome founded a donation program to make up to one million courses of Malarone per year available under carefully controlled conditions to the countries that need it most. Pilot areas selected by the World Health Organization include Kenya and Southeast Asia (Glaxo).

Drug research is connected to a range of academic studies such as biology, pharmacology, medicinal chemistry and toxicology. Pharmaceutical researchers can design novel therapeutic drugs based on these studies above. The invention of new drug can be divided by function into two stages: drug discovery and drug development. Drug discovery is the process by which a new drug candidate is found and identified. Distinctively, bringing a new drug candidate to the market through clinical trials is called drug development. The first part of this essay provides an overview of drug discovery and pre-clinical research and development

Herbal medicines are great alternative for commercially manufactured medicines available in the market. The major reason why herbal medicine differ from modern medicine is because they are produced with 100% natural content. Therefore the plant extract has all the medicinal values that are as effective as modern medicine. Commercially prepared drugs show results quickly but have numerous side effects. However herbal medicines don’t show any side

As our society is evolving so is diseases many drugs that were previously effective to cure certain diseases are simply not as effective any more or on the other hand there isn’t sufficient medicine to battle the current new health problems that are arising with our evolving society for example obesity and a range of cardiovascular diseases. In addition many of the medicine available today either only treats the symptom or cures the disease with the addition of unwanted side effects. Hence, this is why drug discovery and development is vital. It is through drug discovery and development that new medicine is found.

Veterinary medicines are widely used to treat animals. Farmers supplement the animal feed with a wide range of compounds from number of therapeutic classes including antimicrobials, antiprotozoal, ecto and endo parasitic. They get metabolised and traces of their by-products are given out through faeces and urine of the animals which is mixed to the soil and eventually gets accumulated in the water bodies. Some of the medicines are aerosols and can cause effect through air. All these studies show that the use of therapeutic veterinary medicines causes effect on the ecosystem. Keeping in mind one of this global problem, the author has tried to focus on herbal remedies for such anthelmintic diseases especially in poultry birds. Herbal medicines or phytomedicines refers to using a plant’s seeds, berries, roots, leaves, bark or flowers for medicinal purposes. Herbal medicines have long traditional use rather than conventional medicine. Though it enters in the food chain but do not cause any harmful effect on the ecosystem. This study reveals the effect of anthelmintic activity of some of the medicinal plants on helminth parasite Raillietina from the poultry intestine.

In this study, the chemical composition of the essential oil from the resin of Ugandan Canarium was determined, and its anti-termitic activity was established.