The brain has always been one my favorite subjects in biology, because the brain is the control center of the body and it also has an endless amount potential to do anything or solve any problem. It’s amazing to me that at the beginning of life, single celled organisms created a brain like structure called a nucleus and that the brain evolved as organisms became multi-cellular into what we seen now; a huge community of cells that communicate through chemical and electrical signals capable of love, compassion, and invention. However, the brain has a dark-side which compels me to learn more about its structure and function. The brain seems to be the only organ that when diseased can affect a person’s life on every level; socially, psychologically, functionally, and physically. I have seen first-hand what a diseased brain can do to a person, their family, and their community. The devastation is enormous and it spares no one. The brain can become diseased by so many different causes that when I learn of a new disease that affects the brain I become emotionally invested and interested in that subject. I became interested in Amyotrophic Lateral Sclerosis six months ago when I watched a new movie called “Gleason.” That movie illustrates the full progression of ALS. The devastation that I witness on the subject and his family was almost …show more content…
The pathophysiology of ALS can be simplified to the process in which the cells within the central nervous system start to collect aggregates or inclusions within the cytoplasm. These inclusions within the cell can be made up of a large range of materials from defective proteins to damaging free radicals. The result of these inclusions eventually lead to cellular death also known as apoptosis. The pathophysiology behind Amyotrophic Lateral Sclerosis can be linked to two major causes, genetic mutations and an inflammatory response by the
Amyotrophic meaning, “no muscle nourishment” in Greek, lateral meaning where the neurons are in the spinal cord, and sclerosis meaning “scarring.” ALS, often known as “Lou Gehrig’s Disease,” named after the New York Yankee who first brought awareness to the disease in the late 1930’s, is a neurodegenerative disease, which affects the neurons in the brain. The nerve cells in the brain and spinal cord that are responsible for sending and receiving motor signals progressively die off, causing the deterioration of simple motor skills in patients with ALS, such as walking, talking, and eventually speaking and breathing, however thinking is not affected by ALS. Early symptoms cause the person to slowly lose mobility of limbs, but in a matter of a few years, the person loses the mobility of most of their body and will eventually lose the ability to eat and breath, which will ultimately cause death. ALS deteriorates the patient's body, however does not affect the patient's state of mind or sanity while the rest of the body shuts down. People usually get ALS between the ages of 40 and 70. However, there is a growing trend where athletes are getting ALS in their thirties. ALS can be contributed to genetic predisposition, which means that the gene that is responsible for ALS is already in the person’s DNA. In recent studies, however, it was observed that individuals who have had suffered multiple concussions or any other head trauma are
“ Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) responsible for controlling voluntary muscles (muscle action we are able to control, such as those in the arms, legs, and face).” By what A.L.S association.org says. A neurological disease is a disease that affects the brain and gives it many diseases like brain tumors, epilepsy, and, Parkinson's. “A.L.S is a neurological disease that weakens the muscles to where you can barely move or speak” said alsa.org. You can only live up to two to five years with als. A.L.S is a very rare disease every 100,000 people get it. By what alsa.org said. That means 73,571 people has it in the Whole world right now. Als is a very rare
Amyotrophic Lateral Sclerosis (ALS) is a terminal disease, also known as Motor Neurons Disease, Charchot Disease and Lou Gehrig disease. ALS destroys the Central Nervous System (CNS) and causes damage to the upper and lower motor neurons in the brain. Signs and symptoms are characterized as: muscles weakness, muscle atrophy, twitching and reduced muscle reflexes. Eventually the patient will become paralyzed and rely on a tracheostomy and ventilator for breathing (ALS Association [ALSA], 2010).
“A-myo-trophic comes from the Greek language ‘A’ meaning no or negative. ‘Myo’ refers to muscle, and “Trophic” means nourishment-’No muscle nourishment’... ‘Lateral’ identifies the areas in a person's spinal cord where portions of the nerve cells that signal and control the muscles are located.” (“What is ALS?”). Literally, Amyotrophic lateral sclerosis means no muscle nourishment in the spine. In this disease, nerve cells in both the brain and spinal cord slowly die over a period of time. The cells, referred to as motor neurons, control the muscles throughout the body, resulting in death or paralyzation as they degenerate. At any given time, ALS can strike anyone. It is not contagious, however, in about 10% of cases, ALS runs in the family making it somewhat hereditary (“What is amyotrophic lateral sclerosis?”). “The incidence of ALS is two per 100,000 people” (“Facts You Should Know). Most of the time, Lou Gehrig’s disease (ALS), acts on middle-aged and older adults, however there have been noted cases of patients much younger. Considering that a friend or family member can be diagnosed with this horrible disease, everyone should pitch into ALS charities in hope to find a
Picture sitting up to reach for an object but are incapable of moving a muscle. Although completely aware of the surroundings, being unable to interact with any of it as if trapped in a shell, or loved ones noticing increasing instability and offbeat behaviour. These are the lives of Amyotrophic Lateral Sclerosis, or ALS but more commonly known as Lou Gehrig’s disease, and Chronic Traumatic Encephalopathy, or CTE. ALS affects those with the disease by causing full body paralysis. However the disease leaves the brain completely intact. Contrary to ALS is a CTE, a disease that attacks the brain. The build of a specific toxin in the brain is the culprit that leads to the disease which causes brain damage. Concussions are another serious factor
ALS and CTE’s are both results of repetitive head trauma. Athletes in sports such as boxing, football, hockey, wrestling and even baseball have been diagnosed with either of these horrific diseases. Head trauma also known as concussions is a major factor when you receive a big hit to the head, the brain bounces back and forth hitting the inside of the skull, which results in some brain damage which affects you both short term and long term. I believe we should bring more awareness to both ALS and CTE’s to find a cure or more ways to prevent it.
ALS is more commonly known as Lou Gehrigs disease. The progressive disease poisons the nervous system by a chemical that is released after a blow to the head; this chemical is known as Tou. Tou is released into the brain after a blow, poisoning the nervous system causing body muscles to shut down.
ALS (Amyotrophic Lateral Sclerosis) or Lou Gehrig’s Disease is a classified as a degenerative neurological disorder that inhibits motor neurons in the spinal cord and brain to function properly. This disease eventually results in paralysis and imminent death over a period of time. ALS patients have anywhere from a few months, to a couple years to live after diagnosis since their nervous systems are slowly destroyed, rendering the body useless, and sustaining life impossible.
People first need to know what ALS is. ALS is very difficult to diagnose. So far there is no
Everyday, an average of 15 people are diagnosed with Amyotrophic Lateral Sclerosis(ALS) also commonly known as Lou Gehrig's disease. Across the world there are more than 5,600 cases of ALS every year. People all around the world are open to being diagnosed with ALS, it affects people of all ages, races, and gender. Amyotrophic Lateral Sclerosis has affected millions of families and individuals since 1869. However, what is Amyotrophic Lateral Sclerosis, what does life look like for someone with ALS , and what research is being done for a cure?
A distinctive characteristic of ALS is that although the motor neurons die, the brain, cognitive functions and sensory neurons stay intact (Porth & Matfin, 2009). This makes the disease especially devastating because patients become trapped inside their dying body, with a fully alert mind, but are unable to move. It is not known what causes the exact death of the motor neurons in the body, but “five percent to 10% of cases are familial; the others are believed to be sporadic” (Porth & Matfin, 2009, p.
The movie called “Glory” is a historical military based story of the 54th Massachusetts Infantry Regiment. In the movie “Glory” we see the struggle of Colonel Robert Gould Shaw, who is the main character of this movie, and the supporting cast, being his regiment of African Americans recruited to become soldiers during the Civil War. “Glory”, however, Is not just a movie. It is based off of real life events in history during our Civil War, where the African Americans took their first step towards gaining respect, and freedom from oppression.
The Old English epic Beowulf is built around the archetype of the journeying hero. Beowulf exemplifies a classical hero, one who is not immune from hubris, but who channels his strong will into judicious endeavors. Thus, Beowulf dies with the honor and glory befitting a king. His story is one of distinct binaries between good and evil. On the side opposite to Beowulf's goodness is the gruesome Grendel. Grendel is a monster, and the original epic poem does nothing to introduce moral ambiguity that would engender any sympathy for the creature. The creature represents brute force and misanthropic evil, which Beowulf successfully vanquishes. Therefore, Beowulf is established as an existential warrior-hero whose acts of courage and bravery are not just beneficial for his ego but to all of humanity. Grendel is a one-dimensional monster; whereas Beowulf is slightly more complex due to his status and role in society. In 1971, John Gardner retells the medieval tale of Beowulf, from Grendel's point of view. In so doing, Gardner creates a new postmodern hero. Grendel is not the demon that Beowulf and the Danes thought he was; a literary technique that raises all sorts of issues related to stereotyping, discrimination, racism, imperialism, and cultural hegemony. Grendel also reworks the theme of heroism by injecting moral ambiguity into the original story. With Grendel, Gardner replaces a more realistic version of moral right and wrong for the simple dualistic worldview of Beowulf.
In some people with ALS, the parts of the brain that allow us to think, remember, and learn also are affected by the disease (Labby).
This teen fashion model hit the scene march 9, 1959. Wearing nothing but a black and white zebra striped bathing suit, black opened toe shoes, and gold earring. She had blonde hair, red painted lips, full breast, small waist, and long slender legs. And every young girl white or black had to have her and wanted to be her. Barbie was the got to have doll in 1959 till this day worldwide. During my youth my sister and I wanted her too. For Christmas, birthdays and every time we saw a new commercial for her.