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Acute Asthma Case Study

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Signs and symptoms
An exacerbation of asthma is known as a worsening of asthma symptoms with cough and breathlessness. In acute severe asthma, also breathlessness might be very severe as the case that it is difficult to speak more than few words (inability to complete sentences) (Shah and Saltoun, 2012).
On examination, the respiratory rate may be increased (greater than 25 breaths per minute), and the heart rate might be rapid (110 beats per minute or higher). Also, reduction in oxygen saturation levels (but above 92%) are often characterized (Shah and Saltoun, 2012). Examination of lungs with a stethoscope could observe reduced air entry and spread wheeze. The peak expiratory flow can be maintained at the bedside; and the flow in acute severe asthma is lower than 50% of normal flow (Phipp and Gerrardc, 2003).
Very severe acute asthma (near-fatal) is characterized by a peak flow of lower than 33% predicted and oxygen saturation below 92% or cyanosis (blue discoloration, and often of the lips), absence of breath sounds on the chest (silent chest), reduced respiratory ability and drowsiness or visible exhaustion. Abnormalities in the heart beat and …show more content…

The simple description for allergic inflammation in asthma begins with the generation of a helper T2 lymphocyte-driven, which opposed to helper T1 lymphocyte-driven, immune milieu, probably produced by specific types of immune stimulation early in life. This is related to allergen exposure in a genetically sensitive patient. Specific allergen exposure under the impact of helper T2 lymphocytes results in B-lymphocyte sensitization of immunoglobulin E antibodies related to that allergen. The IgE antibody adheres to specific surface receptors on the airway mucosal mast cells (Shah and Saltoun,

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