Acute Diarrhoeal Diseases

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Acute diarrhoeal diseases among the children are one of the most important problems affecting children in the world, reducing their well-being and creating considerable demand for health services (WHO, 2010). Diarrhoeal diseases are leading cause of preventable death, especially among children aged under five in developing countries. Diarrhoea is defined as a child with loose or watery stool for three or more times during a 24-hour period. The frequency and severity of diarrhoea are provoked by lack of access to enough clean water and sanitary throwing away of human waste, insufficient feeding practices and hand washing; poor housing circumstances and lack of access to sufficient and reasonable health care (Gerald et al., 2001). Escherichia coli (EPEC) is a main cause of diarrhoea in infants and children in addition to pathogens such as Salmonella, Shigella, Yersinia, Vibrio, Campylobacter sp., Entamoeba histolytica, and Giardia lamblia in developing countries (Ahmed et al., 2009). Diarrhoeagenic E. coli is the major cause of gastroenteritis in children in the developing world and is associated with high resistance intensity to antibiotics (Ochoa et al., 2009).
Improper recommendation of antibiotics provoked resistance and increased infectious disease mortality not only in developing countries but also in developed countries. Aging populations alter in behaviour and a decline in the development of new antibiotics aggravated a fading situation (Dandekar and
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