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Acute Exacerbation Case Study

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Acute exacerbation of COPD is a medical diagnosis, and therefore is significant to eliminate additional conditions which causes hypoxia and respiratory failure. In this case, pulmonary embolism which could be present in almost a fifth of patients been admitted to hospital who suffer from COPD exacerbation, and therefore it can aggravate an abnormal deficit in the concentration of oxygen in arterial blood which could be causing further V/Q mismatching (ventilation perfusion ratio). Moreover, additional conditions which causes acidosis, reduced tissue perfusion, or increased tissue oxygen requirements, notably systemic sepsis or cardiogenic shock, can also aggravate respiratory failure in COPD patients therefore, must be treated properly. (Brill

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