Acute Kidney Failure (AKF)

The septicemic version is defined as a fast growing bacteria which if not treated properly and fast enough would eventually lead to death. What would happen inside the body would be that the bacteria would disable your body’s ability from being able to clot blood. The infected would become very itchy all over their body to the point where they made themselves bleed from everywhere. Eventually the victim would have massive blood loss leading to

Risk factors for infection can be anything that suppresses the ability of the host to resist the infectious pathogen, including the following: drugs, such as steroids and chemotherapy; disorders that affect the innate and adaptive immune responses, such as cancer, leukopenia, and HIV/AIDS; and a breakdown of the first line of defense, such a trauma, broken skin, or surgical wounds. Patients are at risk for developing sepsis and septic shock if they are very old or very young and have and inability to fight off the infection. Some other risk factors for the

Is sepsis complicated by organ dysfunction, is diagnosed in more than 750,000 patients per year and has mortality rates as high as 28%-50%.

Sepsis is the number one cause of death in intensive care units in the U.S. More than 750,000 cases of sepsis occur each year and about one third of those patients die from it (McKinney, 2014; Ulloa, 2011). Sepsis is a serious condition that is a result of an inflammatory response to infection that can damage organs if left untreated. Severe sepsis occurs when the infection leads to organ dysfunction. Septic shock is when multiple organ failure occurs due to infection and is worse than sepsis and severe sepsis.

Sepsis is a rapidly progressive illness that must be treated early with antibiotics and supportive care.

Under the Core measures, Sepsis is one of the problem-focused trigger for systemic infection and if untreated which can lead to death. In United States, it is the 11th leading cause of death and consumes the large amount of costs about $20.3 billion in 2011 (Jones et al.,2016). According to Centers for Disease Control and Prevention (CDC), more than 1.5 million people diagnosed with sepsis, and at least 250,000 patients die from that yearly (CDC, 2017). The evidence-based research revealed with results of certain pre existing conditions, pathophysiological studies, preventive measures and sepsis bundle for treating and preventing sepsis to save the life of the patients.

Sepsis is a life-threatening and potentially fatal condition caused by the body’s reaction to an infection. Sepsis occurs when chemicals normally released in the bloodstream to fight infection trigger inflammation throughout the body. This can result in damage to multiple organs, which can cause organ damage and, in some cases, death.

Acute renal failure condition is diagnosed and retitled as acute kidney injury. The purpose of the change of terminology was to encompass the full spectrum of the clinical manifestations associated with the syndrome. This includes a range from a small decline in kidney function to a severe impairment. Furthermore, the acute condition is characterized by a rapid loss of kidney function. In addition, associated manifestation(s) may be displayed as a rise in serum creatinine or a reduction in urine output. As a result of increase of serum creatinine or decline in urine output may developed and aggress to the clinical manifestation azotemia.

Septic shock results from bacteria that multiply in the blood and then releases toxins that decrease blood pressure, thus, impairing blood flow to cells, tissues and organs. It is an acute infection, usually systemic, that overwhelms the body (toxic shock syndrome) (Huether & Mccance, 2012). This

As sepsis progresses, tissues become less perfused and acidotic, compensation begins to fail, and the patient begins to show organ dysfunction. The cardiovascular system also begins to fail, the blood pressure does not respond to fluid resuscitation and vasoactive agents, and signs of end-organ damage are evident (e.g., renal failure, pulmonary failure, hepatic failure). As sepsis progresses to septic shock, the blood pressure drops, and the skin becomes cool, pale, and mottled. Temperature may be normal or below normal. Heart and respiratory rates remain rapid. Urine production ceases, and multiple organ dysfunction progressing to death occurs. Adventitious lung sounds occur throughout the lung fields, not just in the upper fields of the lungs.

This leads us to the next step in the pathophysiology of Sepsis. Stage 2 of sepsis, which is when SIRS plus the confirmation of an infection has been made. At this stage, the patient’s body has been continuously fighting something in their body and it is starting to have an effect on the patient. Signs and symptoms of sepsis are often nonspecific and include the following: Fever, chills, or rigors, Confusion, Anxiety, Difficulty breathing, Fatigue, malaise, Nausea and vomiting. It is important to identify any potential source of infection. Localizing signs and symptoms referable to organ systems may provide useful clues to the etiology of sepsis and are as follows: Head and neck infections: Severe headache, neck stiffness, altered mental

et al., 2008). Sepsis is a frequent cause of admission to intensive care units (ICUs) and it

On his death certificate they declared his cause to be Sepsis by an unknown origin. Sepsis is defined as a systemic inflammatory response that occurs within the body due infection within the bloodstream. Common sites for infection that cause sepsis include pneumonia, kidney infections, or abdominal infections. The infection can be either bacterial, viral, or fungal. The most common gram positive organisms include staphylococcus aureus and enterococci. Common gram negative organisms include pseudomonas species and E. coli.

postrenal, which is when there are obstructions in the urinary tract. This one affects the

research paper, is to provide a general overview of the causes of kidney failure, shedding light on it