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Acute Respiratory Distress Syndrome Analysis

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Acute respiratory distress syndrome is a disease process that requires specific, intensive care to increase the odds of patient survival. Due to the rapid and significant decline in a patient’s ability to maintain their respiratory status, ventilation techniques in treating acute respiratory distress syndrome are specific and unique. Multiple techniques have been studied extensively and a few stand above the rest in changing the mortality rate. High frequency percussive ventilation and high frequency oscillatory ventilation may be good options for ventilating some of the most critical patients.
Understanding acute respiratory distress syndrome (ARDS) is a critical aspect of managing a patients ventilatory needs. The definition of ARDS is “the …show more content…

A simultaneously published trial called Oscar did not seem to have the same outcomes for patients receiving HFOV. There were multiple differences between Oscillate and Oscar, the most obvious being the use of the Novalung R100 in the Oscar trial. This was a new ventilator to the clinicians and hospitals participating in Oscar therefore, all clinicians participating in the study were required to go through 198 training classes to learn the specifics of the Novalung R100 ventilator. The outcome of the Oscar trial was only a 2 percent difference in mortality between conventional ventilation using a lung protective mode versus HFOV. This trial also had a similar outcome with vasoactive and neuromuscular blocking medications, Young et al states that this increase is due to the Novalung R100 not allowing for a patient to spontaneously breath on top of the oscillatory mode, therefore these medications were required to aide in patient- ventilator synchrony (Young, …show more content…

The oscillate trial reported a 35% conventional ventilation mortality rate compared to 41.1% mortality rate in the Oscar trial. Both trials demonstrated that mortality rates in utilizing HFOV is higher, 47% in the Oscillate trial and 44.1% in the Oscar trial. The Oscar trial patients who were randomized to the HFOV had a closer margin of mortality to the conventional group with only a difference of 2% favoring conventional ventilation, compared to the Oscillate trial which concluded with a difference of 12% also favoring the conventional ventilation

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