Addiction and the Reward Circuit Essay example

It is shown that people that tend to be involved in the use of drugs do so after making a voluntary choice (Heyman, 2009). The major use of drugs for social and non-medical preferences can lead to dependence and further addictions, it is a choice that people tend to make and from that it can lead to wanting it more, do it more with friends and further it becoming an addiction, that then effects the brain and body. When drugs are used in the wrong way they can cause many health issues but some people still tend to refer to drug addiction as a disease. Yes, There has been compelling evidence that addiction is a disease, however the result shown are weak and inconclusive. Results of different brain scans are shown by The National Institute of Drug Abuse (2017) are used to back up that addiction in fact is a disease, however the brain scans used in this research are not symbolic of any abnormal changes. The research by The National Institute of Drug Abuse do point out that changes in an individual’s brain is shown as evidence that addiction is a brain disease, however this argument can be shown as mistaken as changes in many human brains can be seen as not exclusive in addicts, although they can occur when a person is normal (Branch,2011). To top it off the information that is stated by the NIDA however doesn’t show evidence of the behaviour of addicts being involuntary or

The three models of addiction examined in this week’s readings include the medical model, the psychosocial model, and the disease of the human spirit model. The medical model “rests on the assumption that disease states are the result of a biological dysfunction, possibly one on the cellular or even molecular level” (Doweiko, 2012, p. 333). Many consider this model and “maintain that much of human behavior is based on the interaction between the individual’s biological predisposition and the environment” (Doweiko, 2012, p. 333). Individuals under this model view free will “as an illusion” (Doweiko, 2012, p. 333). There is controversy regarding this model as “to the degree to which the

The ponderance that Brain = Behavior and the inherent ramifications of such proves no more fascinating than when addressed in the context of "Addiction and the Brain". Essential to consider is:

Brain chemistry can affect different addicts more then others. Drugs and alcohol are more of the main addictions that brain chemistry affects. Once taking these addictive substances your internal natural drug dopamine is lowers causing you to seek more external addictive substances. This causes craving and makes it a lot harder for the addict to stop. In Olds and Milner’s later experiments, they allowed the rats to press a particular lever to arouse themselves, to the effect that they would press it as much as seven-hundred times per hour. This region soon came to be known as the "pleasure center". Using drugs and alcohol stimulates the pleasure center in the brain that makes your brain think, “feels good- want more“. This can make it increasingly harder for an addict to stop using, until they hit a point called “rock bottom”. This is where choice comes back into play.

Addiction causes changes in the chemical makeup of the brain itself. Once the chemicals from the substance are introduced past the blood brain barrier the chemical reactions are changed. The neurons and neurotransmitters function a differently. Survival instincts that are the responsibility of the deeper recesses of the brain are changed. Cancer cells are changed by chemicals or radiation so too are

The history of addiction goes back centuries, and unfortunately, there is still a long way to go for people to realize the effects of chemical substances do more harm than good. The difference between drug use and abuse relies heavily on a person’s dependence on the substance. The line between the differences is often very fine. Depending on other factors involved, such as morals, values, environment, and genetic predisposition, the line will most likely be crossed without regard to the consequences until treatment and recovery are the only options left. This is essay compares two theoretical explanations

This research paper will evaluate the biological aspects of addictive substance or behavior and how it affects the brain and organs. Biological aspects include dopamine levels that are replaced in the brain due to the reward system being overtaken and the absorption rate of the drug once it is ingested will be discussed. The biological aspects are extensive and permanent if the individual does not get the help they need. Furthermore the clinical issues of addictive substance or behavior will be discussed along with medical treatments and ethical issues. This includes treatments such as counseling

According to the biological perspective, drug use may start off as casual, but through continued use, it produces changes in the brain that influences the onset and maintenance of drug addiction. (Horvath et al., 2013). Drugs have their most prominent effects on the function of neurotransmitters. Almost all major drugs of abuse activate the reward system and cause a flood in the levels of dopamine which is a neurotransmitter that is involved in pleasure. As a result, not only do people learn to associate drug use with pleasure, but the brain also starts to reduce its own natural dopamine production in adjustment to the levels of dopamine produced by the drugs. This is called tolerance, and the consequences of tolerance are highly influential

As results of scientific research, we know that addiction is a disease that affects both the brain and behavior. A disease is an interruption, cessation, or disorder of a body system, or organ structure, or function; according to Stedman’s Medical Dictionary. (Sheff ,2013) cites, the disease od addiction has an etiologic agent, identified by a group of signs and symptoms or consistent anatomic alterations. There are significant changes in the brain. The American Society of Addiction Medicine (ASAM) states that addiction is a primary, chronic disease of brain reward motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristics biological, psychological, social and spiritual manifestations. This is reflected in an individual pathology pursuing reward and /or relief by substance use and other behaviors. (Addiction is characterized by inability to consistently abstain, impairment of behavioral control, craving, diminished recognition of significant problems with one’s behaviors and interpersonal relationships and dysfunctional emotional responses. Like other chronic diseases, addiction often involves cycles of relapse, and remission. Without treatment or engagement in recovery activities, addiction is progressive and can result in disability or premature death. (ASAM Adopted as Policy, February

Across all addictions, there is a central theory as to how such an addiction can occur. The common mechanism of all addictive substances is the activation of the brain’s “reward system”, made up of dopaminergic neurons of the midbrain and their extensions to the limbic system (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272277/). This system is normally used in advancing evolutionary fitness promoting activity, such as sex, food, or social interactions (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272277/). In such normal natural behaviors, the reward system activity is relatively brief and weak. However, addictive substances abuse the system’s circuitry, causing

Basic neurobiological research has improved our understanding of the biological and genetic causes of addiction. These findings have helped establish addiction as a biological brain disease that is chronic and relapsing in nature (Leshner, 1997). As the central nervous system is considered to be the communication pathway to the entire body with the brain being its control mechanism. The brain processes sensory information from throughout the body, guides muscle movement and locomotion, regulates a multitude of bodily functions, forms thoughts and feelings, modulates perception and moods, and essentially controls all behavior (Leshner, 1997). The body and brain then become defendant on this stimuli, as the body and brain adjust to the rewards of receiving this type of sensation. This is where the substance abuse and addiction problems

Drug addiction is a brain disease because drugs change the brain’s structure and how they work. Over a period of time drugs start to affect the brain by challenging an addicted person’s self-control and interfere with their ability to resist intense urges to take drugs. “Most drugs affect the brain's reward circuit by flooding it with the chemical messenger dopamine. This overstimulation of the reward circuit causes the intensely pleasurable "high" that leads people to take a drug again and again. Over time, the brain adjusts to the excess dopamine, which reduces the high that the person feels compared to the high they felt when first taking the drug—an effect known as tolerance. They might take more of the drug, trying to achieve the same dopamine high.”, States National Institute on Drug Abuse. After long term use of drugs it affects functions such as learning, judgment, decision-making, stress, memory, and behavior. Even though an addict knows this, they still use

The purpose of this paper is to examine the article, “The Brain’s Rewarding System & Addiction” (2004) by Katharine P. Bailey, MSN. In this article, I did not find a general hypothesis. Studies in this article show that most drugs directly or indirectly cause selective elevation of dopamine levels in the nucleus accumbens (NA), the ventral tegmental area (VTA), and the limbic system, consequently called the reward center of the brain (Bailey, 2004). Behaviors that bring pleasure and are also crucial to existence (eating, drinking, and sex) also activate the same reward circuitry, however, activation of this circuitry by addictive drugs can be much

Cocaine, on the other hand, has been found to have a profound effect on increased dopamine activity. Kennedy & Hanbauer (1983; cited in Karch, 2007) found a strong correlation between cocaine binding and the inhibition of dopamine uptake, and therefore proposed that dopamine transporters are binding sites for cocaine. Such research, which correlates strong reinforcing properties of cocaine with inhibition of dopamine transporters, suggests that cocaine has a more significant affect upon dopamine, than than it has upon serotonin and noradrenaline. The excessive role of dopamine can explain the high degree of pleasure that users of cocaine experience, as well as depression and cravings, which follow.

“The overstimulation of this reward system, which normally responds to natural behaviors linked to survival (eating, spending time with loved ones, etc.), produces euphoric effects in response to psychoactive drugs. This reaction sets in motion a reinforcing pattern that “teaches” people to repeat the rewarding behavior of abusing drugs ”(“Understanding Drug Abuse). Using addictive drugs floods the limbic brain with dopamine, taking it up to as much as five or ten times the normal level. A person with elevated dopamine levels now has a brain that begins to associate the substance with an outside neurochemical reward (“Your Brain on Drugs”). As a person continues to abuse drugs, the brain adapts to the overwhelming surges in dopamine by producing less dopamine or by reducing the number of dopamine receptors in the reward circuit. The result is a lessening of dopamine’s impact on the reward circuit, which reduces the abuser’s ability to enjoy the drugs, as well as the events in life that previously brought pleasure. The decrease in normal dopamine levels encourages the addict to keep abusing drugs in an attempt to bring the dopamine function back to normal, except now larger amounts of the drug are required to achieve the same dopamine high, an effect known as tolerance (“Understanding Drug Abuse ). That is what leads to the state of addiction, which leaves the person in a cycle of craving, using, withdrawal, and relapse.