Addison’s Disease is a rare disease that attacks the endocrine system, it is also known as Hypoadrenocorticism. There are many different pathological reasons that Addison’s disease can occur. The most initial sign that Addison’s disease has occurred is a colored pigmentation of the oral cavity. The symptoms of this disease will progress over time. The condition can worsen if the patient is involved in any form of an accident. If an accident occurs, it can be life threatening. Addison’s disease typically affects 1 in 100,000 people. This disease does not discriminate, it affects all ages, genders, and races equally. The predominant cause of Addison’s disease remains to be tuberculosis. This disease was named after Thomas Addison a doctor …show more content…
Addison’s disease typically does not appear until about 90% of the glandular tissue has already been destroyed. The bronzing or “Hyperpigmentation” of the skin is usually seen more on sun-exposed skin and general pressure point areas like the elbows and knees. Vitiligo may also be seen in association to the hyperpigmentation due to the idiopathic Addison’s disease due to the autoimmune destruction of melanocytes. Hyponatremia and Hyperkalemia are also associated with Addison’s disease, patients usually complain of gastrointestinal upset as well as anorexia, nausea, vomiting, diarrhea, and a salt craving. These symptoms can be more severe if an accident involving the patient occurs, for example lower pain in the back, abdomen, and legs, as well as extreme vomiting and diarrhea followed by dehydration, low blood pressure, and a loss of …show more content…
As for a patient in Addisonian crisis this treatment will be conducted by injecting a potent form of steroid through a needle directly into a vein. As for dehydration and salt loss these will be treated with a balanced solution through an IV. For patients with the lowered blood pressure symptoms they will be taken care of with special medications to elevate the blood pressure until the steroids are in full effect. Patients with this disease will need to take hydrocortisone which is a steroid preparation as well as a replacement of aldosterone by mouth for the rest of their
Primary treatments include antibiotic therapy, Fluid resuscitation, and crystalloid. Potential treatments depending on patient status include vasopressors and steroids, ventilator, renal dialysis, blood transfusion, and surgery.
1. These diseases include vitiligo, rheumatoid arthritis, anemia caused by not having enough vitamin B12 in the body and leads to extreme fatigue, celiac disease, and autoimmune hepatitis, a disease in which the immune system attacks liver cells.
Case study: Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and Diarrhea. The patient has a history of drug abuse, and possible Hepatitis C. HL is currently taking the following prescription drugs: Synthroid 100 mcg daily Nifedipine 30 mg daily Prednisone 10 mg daily Drug review Synthroid is a hormone used to treat patients with dysfunctional thyroid glands. It is administered in small doses to reduce the adverse side effects on patients (Gerald, 2013).
Some symptoms that can also occur in some patients are nausea, vomiting, and diarrhea. The previously mentioned symptoms are fairly common with many different disorders however some of the most defining symptoms of Addison’s disease are low blood pressure that drops when standing, and skin changes or hyperpigmentation that is most visible on areas of the body such as scars, knees, elbows, knuckles, lips, and skin folds. Patients can also suffer from depression, irritability, and a craving for salt, and amenorrhea in female patients.
Adrenoleukodystrophy, or ALD, is a deadly genetic disease that affects 1 in 35, 000 people. It most severely affects boys and men. It knows no racial, ethnic, or geographic barriers. ALD is currently not curable, but doctors can help slow progression. Symptoms of ALD include weak muscles, poor appetite, weight loss, paralysis, seizures, developmental delay , mental retardation , and vision and hearing impairment. Treatment methods differ depending on the type of ALD one has. Steroids can be used to treat Addison’s disease. Other treatments include: physical therapy to loosen muscles, medication to relieve seizures, or taking Lorenzo’s oil to help lower elevated VLCFA levels. This can harm one’s spinal cord, brain, adrenal glands, and testes.
How will you explain this to a patient? Jaundice occurs when your liver doesn’t metabolize bilirubin, a yellow pigment formed by the breakdown of old red blood cells, the way it’s supposed to. Jaundice may indicate a serious problem with the function of your red blood cells, liver, gallbladder, or pancreas.
The primary symptoms of Addison’s disease include fatigue, weight loss, darkening of your skin, muscle weakness, and weak, irregular pulse. The secondary hypofunction is almost identical to the primary Addison’s symptoms except without darkening of the skin, which is also called hyperpigmentation. If you’re not treated ASAP Addison disease will degrade into addisonian crisis. The symptoms of addisonian crisis is shock due to insufficient blood in the body, pain in the lower back, abdomen, or legs.
Cyanosis is the bluish discoloration of the skin. The disease is mostly on the skin but can also be in the mucus membrane due to excessive concentration of deoxyhemogoblin in the blood caused by deoxygenation. There are two different types of Cyanosis which are Central and Peripheral. Central is around the core, lips, and the tongue. The Peripheral is only on the extremities of the body or fingers. Cyanosis comes from the Greek word Kuaneos which means “dark blue”. Cyanosis is caused by the lack of oxygen, when the body lacks oxygen the blood turns bluish purple. The lack of oxygen in the blood supply allows the body parts to turn, such as the ail bed, skin, or mucous membrane, causes that body part to take that bluish tint. When the patient
One of these symptoms is jaundice, which is characterized by yellowish skin and eyes because of an inability of the liver to remove bilirubin from the blood. Patient with cirrhosis also suffering from itching, due to deposited bile's products in the skin. This patient also suffers from accumulation of fluid in legs that is called edema. As a result of the blockage of blood flow via the liver, fluid accumulation in abdomen which is worsen by the decrease in protein production. Other symptoms include fatigue, weakness, loss of appetite, weight loss and nausea. As the disease progress, complications may develop ,such as varices that happens with cirrhosis patient when the blood flow through the liver slows, so the blood from intestine go back to the vessels of the stomach and esophagus, these vessels are not meant to carry this much of blood so they dilate (varices), with increasing
Addison’s Disease goes unnoticed in a lot of people. Addison’s is sometimes called the uncommon common disease because people are walking around with it but the symptoms are so closely associated with other illnesses, go undetected. Knowledgeable professionals are even hard to find. People knowing living with Addison’s Disease are constantly in fear not knowing if they were to go in a crisis, who would have enough knowledge about the disease to assist. Yes, most first responders, ER staff, physicians’ offices, are clueless. There just isn’t enough information to about this disease to help people with it which is why I chose to be an advocate. My wife has the uncommon common disease and immediately our lives would change. I won’t say it was for worse nor will I say for good, it’s just changed. There are all kind of foundations out there trying to raise awareness of this disease but they are mainly in the larger areas and major hospitals. I want as many people as possible to know about this disease that really does makes it “impossible” to get out of bed, to know about this disease that makes you feel “sick as a dog”. I hope to help at least one person know more about this disease each day. Let’s raise awareness.
This is an organ-specific autoimmune disorder with a genetic predisposition determined by the major histocompatibility locus on chromosome 6.21 It is associated with other autoimmune conditions such as Addison's disease and Hashimoto's thyroiditis. The presence of certain human lymphocyte antigen (HLA) haplotypes predisposes to the disease. The history of the disease lies on a genetically predisposed individual who suffers from some kind of environmental trigger that culminates in aT-ceil-mediated destruction ofpancreatic f3 cells . Certain important environmental triggering agents include viral infection" and cow 's milk proteins.
Some skin problems with diabetes are linked to insulin resistance. An example is acanthosis nigricans. The gets a dark tan or brown and thickens in areas such as skin folds including the armpits, groin, back or sides of the neck and under the breast, as well as the knuckles. It may precede diabetes and often occurs in people who are overweight. Losing weight can help.
Addison’s disease is a rare endocrine disorder caused by deficiency of cortisol that presents in a chronic or acute course. Primary adrenal insufficiency is most often a result of autoimmune destruction of the adrenal glands and can lead to an acute crisis. Common symptoms of addisonian crisis are sudden abdominal pain, pain in legs, or lower back, nausea,
Symptoms of Albinism vary from person to person. Many people think albino and picture pure white hair, the palest skin, and red eyes, but it really depends on the amount of pigment each person has. The skin of a person with the albino mutation is usually paler than most. This causes people with the mutation to be at a higher risk for skin cancers, and they can get sun damage easier than others. It is very important to stay protected out in the sun if a person is albino. For some people with the mutation they can start to produce melanin in their childhood and teen years which can cause a slight change in the
causes many issues and symptoms to certain individuals, the disease can be serious and deadly.