Have you heard of diseases that destroy the body from within its self? I’d like to take this time to tell you about one called Addison’s disease. Addison’s disease can be a minor illness or, if not treated, it can be deadly. Addison’s disease was named after “Thomas Addison who was born in April of 1793 and he died June of 1860”. In 1812, Thomas became a medical student at the “University of Edinburgh”. In August of 1815, Thomas became an M.D. with his thesis of “Concerning Syphilis and Mercury”. In 1837, Thomas became a full physician to Guy’s Hospital. In 1838, Thomas was elected a “Fellow of the Royal College of Physicians”. Addison’s disease was first discussed in 1714, when he wrote a short article in the “London Medical …show more content…
Addison’s disease can sometimes be referred to as “Adrenal Insufficiency”. Addison’s disease is so rare “only 1 in 100,000 (have) it”. This disease can be present in men or women and can happen at any age. Before I explain what we are going to see in people that have Addison’s disease, I would like to elaborate on what causes it. The number one cause or most common cause is “Idiopathic autoimmune adrenocortical insufficiency”. This results from autoimmune atrophy, fibrosis, and lymphocytic infiltration of the adrenal cortex. This usually spares the adrenal medulla. Of the reported cases, this accounts for 80%. The kidneys or the adrenal glands are another reason for the lack of production of the hormones. With the autoimmune disorder, the body mistakenly attacks the adrenal glands, destroying the outer layer of the glands. Long lasting diseases, or infections, such as TB, HIV, and some fungal infections can cause Addison’s disease. If a patient has cancer somewhere in their body and it spreads to the adrenal glands, it could also cause Addison’s. Prolonged or improper use of steroid hormones, such as prednisone, can cause secondary adrenal insufficiency. Less common causes can be caused by pituitary tumors or damage to the pituitary gland during surgery or radiation. In some cases, hereditary predisposition has been found to be the cause. Wrapping up the causes, the main causes are, adrenal dysgenesis (the glad has not
The introduction to Addison’s disease. It is basically when your body doesn't produce enough of the hormone cortisol, which pretty much means that you don’t have adrenaline, because cortisol is what produces adrenaline. I believe that Addison’s disease is a terrible disease. Your body does not get the adrenaline rush during sports, or whenever your body gets one, at the time when you need one. Addison’s disease is a very rare disease. Cortisol comes from your adrenal glands. The adrenal glands are located on top of your kidneys.(One gland on each kidney) So, if you are ready to learn about how Addison’s disease affects people’s everyday life?
Addison’s disease is a disorder of the endocrine system. It is a hormonal disorder that can strike anyone, any gender at any age. Addison’s disease has also been called Adrenal Insufficiency (hypocortisolism) because the root of the disease is in the adrenal gland not producing enough of the hormone cortisol, or sometimes not enough of the hormone aldosterone to satisfy the body’s needs.
1. Cushing's disease is a hormonal disorder which is caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. It is sometimes referred to as hypercortisolism, it is fairly rare and it most commonly affects adults between the ages of 20 to 50. There is an estimated 10 to 15 of every million people who are affected every year.
Many of the doctors of the time were amazed at the horrible disease. Physicians were stumped about cure or even remedies of this illness. The only advice they could offer is to get away from it and start off new
Addison 's disease is a disorder that occurs when a person 's adrenal glands produce insufficient amounts of certain hormones. When Addison 's diseased was first discovered the endocrine system was not yet completely understood therefore the disease itself was for the most part fatal. After years of research and medical breakthroughs Addison 's disease is now a disease in which someone can live a normal life as long as a daily dose of replacement
Alongside with organs, bones, and tissues, the human body also functions through hormones. Some of these hormones are produced by the adrenal glands which are located right above the kidneys. Adrenal glands produce hormones that give vital instructions to almost every organ and every tissue in your body. When someone’s adrenal glands do not produce enough amounts of certain hormones such as cortisol and aldosterone, this often leads to Addison’s Disease.
Consequently, Addison’s disease is said to affect approximately 1 in every 10,000 people and if left untreated, may be fatal (2).
“In 1855, Thomas Addison first described adrenal insufficiency, which was subsequently named after him. The basis of Addison disease has dramatically changed since its initial description. Originally, the disease usually resulted from
I hope that by the end of this paper, the reader will have a lot better knowledge over this disease. It is in my opinion that everyone who would like to go into the medical field, study the different types of diseases and illnesses as it will make us more empathetic to our patients and the way they may be
The disease was first noted in 1786 by Caleb Hillier Parry 1755- 1822, physician from General Hospital, Bath, England. His account was published posthumously in 1825.
Addison Disease defined as a rare condition that affects the adrenal gland both in men and women alike. Addison Disease occurs when the body does not make enough cortisol or even sometimes aldosterone due to the autoimmune system attacking the adrenal glands. Cortisol needed to regulate the bodies response to stress. Aldosterone needed to help the kidneys regulate the amount of salt and water in the body to keep blood pressure under control, to low aldosterone causes hypotension. Infections such as Tuberculosis, HIV, Fungal Infections (and sometimes even Bacterial Infections), and Cancer cells can harm the adrenal gland.
To understand the practices of the doctors of the Yellow Fever epidemic, there has to be an understanding of eighteenth century medical education. An examination is vital to understand why the physicians of the epidemic treated their patients the way they did. This thesis will outline the education of the University of Edinburgh. Edinburgh was the forerunner in medical education in the eighteenth century. It was a hub of the best and newest medical knowledge. The university offered both lectures and clinical practice which attracted aspiring American physicians. Edinburgh’s model of education is seen in the foundation of American apprenticeships and its first medical school in Philadelphia. Although Edinburgh was considered to be the most prestigious
CT of the abdomen and pelvis with contrast is a tool to identify pathology in a large number of conditions. In patients with endocrinopathies, pancreatic and adrenal lesions may be identified that could relate to their condition. In this patient, it is theoretically possible for the Cushing syndrome to be caused by a cortisol-secreting adrenal tumor. However, Cushing syndrome is much more commonly secondary to exogenous glucocorticoids rather than endogenous glucocorticoids; therefore, stopping the patient’s prednisone use should be the first step. If the symptoms of steroid excess persist, then a CT of the abdomen with a three-phase adrenal protocol could be performed to identify a potential adrenal
Addison’s disease is the outcome of a loss of cortisol and aldosterone secretion. This is a result of the obliteration of the adrenal glands. The most common cause of Addison’s disease was tuberculosis up until the mid twentieth century. Then, it was found that an autoimmune reaction that makes antibodies against the adrenal glands was also a major cause of this disease. Other less common causes like fungal infections, a virus associated with AIDS, and cancer cells were also found.
The evidence shows that the discovery of the origins of Lyme Disease has been particularly difficult to determine. One of the very first physicians who reported on an expanding skin rash was Swedish dermatologist Arvid Afzelius. He eventually published his findings and hypothesized that the rash may be associated with the Ixodes