Advantages And Disadvantages Of Calcium Phosphate Tablets

"Several medical companies are developing new porous coatings for implants that promote and increase bone ingrowth and reduce bone shielding effects by the use of titanium-based foams or scaffolds," he explained. "Today's technology works by plasmaspraying the powder onto the implant.

Osteoblast- cells which build bone by removing calcium and phosphates form the blood in the presence of the enzymes alkaline phosphates secrete by

What is osteoporosis exactly? Literally, osteoporosis means “porous bone”. Derived from oste/o, meaning bone, and –porosis, meaning the condition of being porous. It is an imbalance between bone resorption and bone formation. Clinically defined as a disorder characterized by compromised bone strength leading to an increased risk of fracture (Lane, 2006). Normal bone structure includes an extracellular matrix with mineralized and non-mineralized components, which gives the bones their mechanical properties, as well as collagen and mineralized osteoid cells. Calcium concentration is extremely important is determining the compressive strength of the bone (Bethel, 2015). The structure of bone in an individual with osteoporosis has lost mineralization and collagen due to a decrease in the production of these components as a result, the bones become porous and brittle. Bone is living tissue, constantly being broken down and reformed through out life. Derived from

Another component of bone and teeth is phosphorous and calcium, with calcium being required for blood clotting along with aiding in the contraction of muscles.

Hydroxyapatite is a chemical in teeth that makes them much harder than boned. Because of this teeth do not decay, and therefore under certain conditions are still present many million years after the bones have diminished.

Natural bone tissue possesses a nanocomposite structure that provides appropriate physical and biological properties. For bone tissue regeneration, it is crucial for the biomaterial to mimic living bone tissue. Since no single type of material is able to mimic the composition, structure and properties of native bone, nanocomposites are the best choice for bone tissue regeneration as they can provide the appropriate matrix environment, integrate desirable biological properties, and provide controlled, sequential delivery of multiple growth factors for the different stages of bone tissue regeneration. Bioactive polymer/hydroxyapatite (nano) composites are currently being intensively investigated as materials for promotion of bone tissue regeneration

In 2011, Professor Susmita Bose, of Washington State University, modified a ProMetal 3D printer to bind chemicals to a ceramic powder, creating intricate scaffolds that promote the growth of bone in any shape. Prof. Bose’s goal is to, one day, be able to implant the bone scaffold with bone growth factors in such a way that the implant is dissolved by natural bone material in even load-bearing bone structures.

Edward Group (2015, para. 3-10), Calcium Orotate is the most effective form of a calcium supplement and is great for supporting calcium levels. Other forms of calcium are calcium carbonate, calcium citrate, oyster shell calcium, calcium gluconate, calcium lactate, calcium phosphate, and calcium citrate malate, (Group, 2015, para 3-10). This means that there are several different kinds of calcium supplements but they are all not created equal. Some calcium supplements are more bioavailably effective than others. Other calcium supplements should be avoided. “Calcium carbonate is not high in bioavaility and requires the production of extra stomach acid to be absorbed. It is also one of the cheapest and most prevalent forms of calcium supplements sold today”, (Group, 2015, para. 3).

Calcium phosphate is found in cow milk. Seventy percent of bone and ninety percent of tooth enamel contains a calcium phosphate mineral known as bone mineral or hydroxyapatite. Calcium phosphate is often used to prevent and treat calcium deficiencies. Calcium phosphate contains 40 percent elemental calcium, tied for the highest of any calcium

Throughout life the skeletal system is constantly changing. Bone modeling, formation and growth of bones, occurs from birth to early adulthood resulting in increase in skeletal mass and changes in skeletal form. Naturally the peak bone mass is achieved in the third decade of life, meaning the bones are at their strongest state in human development. Bone remodeling, a response to micro trauma and stress on the bone, is a dynamic process that also occurs through life. Bone is composed of collagen type 1, a protein, minerals such as calcium and phosphate and bone forming cells (osteoblasts and osteocytes) as wells as bone resorbing cells known as osteoclasts. Calcium is a main contributor of bone strength. In fact 99% of calcium is stored in bones and teeth with one percent remaining in the blood. The process of bone remodeling is activated by stressors such as weight bearing and is necessary to maintain bone mass in an adult. It’s a dynamic process in which bone resorption is always

In this project this scientist will be testing which calcium supplement works best to increase density in a bone with osteoporosis. In order to perform this experiment, this scientist will first be deteriorating the bones in vinegar so they are much like a bone with osteoporosis. Then this scientist will be recalcifyng the bones by soaking them in water and calcium supplements. Finally comparing the density of each bone before and after the calcium supplements, this scientist will determine which calcium supplement worked best in increasing bone density.

Hypophosphatemia is a condition where there is a lack of phosphate in the blood. This lack of phosphate results in a low bone density. According to the Journal of Bone and Mineral

The bone is hard, made up of collagen together with inorganic substances like calcium, magnesium and phosphorus.

They undergo a mineralization process to calcify the bone into a harden material. First, the matrix of the bone, a mixture of both collagen and water, plus other organic components are first laid down first. Osteoblast cells secrete type 1 collagen, glycoproteins, proteoglycans, membrane-enclosed vesicles with alkaline phosphatase and toehr associated enzymes as well as a product known as osteoid into the matrix. The osteoblast secretions bind with calcium with high affinity and enzymes hydrolyze phosphate ions from various macromolecules creating a high concentration of ions. The high ion concetrations causes calcium phosphate crystals to form and grow to mineralize further into a compound known as hydroxyapatite. Hydroxoapatie surround collagen fibers and merge into a solid bony

Osseous tissue contains specialized cells, cell products, and a fluid matrix. The distinctive solid, stony nature of bone results from the deposition of calcium salts within the matrix. Crystals of calcium phosphate account for almost two-thirds of the weight of the bone. The majority of