Advantages And Disadvantages Of Kidney Dialysis Machine

During the transitioning process to the new hemodialysis unit, Ms. Conlon anticipated the challenges acquired by learning to set up and use new water equipment in an acute situation. In response to this, Ms. Conlon created and implemented a reverse osmosis flow sheet to assist her colleagues with the quick set-up of the portable RO in the ICU care setting. This tool resulted in a smoother transition for her colleagues, improvement in the delivery of care to the acute dialysis patient, and a decrease in the possibility of staffing overtime.

William Koff (“The History Dialysis”). Koffs machine is considered the first modern drum dialyzer (“Dialysis”). By the 1950’s Koffs invention of artificial kidney Dialysis had solved the problem of renal failure (“Dialysis”). Although some patients with kidney failure which kept them on the dialyzer for daily treatment. However Dr. Belding Scribner solved that problem by connecting the patient with plastic tubes, one inserted into an artery and the other one into the vein (“Dialysis”). Helping the patients move around easier, making their lives

To what biological structure is the dialysis bag comparable? How is it similar? How is it

Research indicates that small molecules are the most common and more easier form of drug therapeutics. Small molecules are easier and more cost effective to produce. However because they are chemically produced and are ingested through tablets, it makes it difficult for them to have a lasting affect within the body. Researchers are looking into using biologics as an alternative form of therapeutic for certain diseases. Biologics are naturally synthesised from various sources. It has been known that biologics would have a longer “life expectancy” within the body because it would be given intravenously, directly into the blood stream avoiding it from being broken down by the G1 tract which would occur with a small molecule (Bayer HealthCare,

Compounding is an important facet of pharmaceutics that allows the formulation of specific drugs for individual patients. The work done at compounding pharmacies permits the development of medicinal products for patients that cannot tolerate certain components from mass production pharmaceutical companies. These individuals may require uniquely compounded agents to be flavorless, preservative-free, dye-free, liquid, solid, or more. These specialty production facilities are necessary for therapy and an acceptable quality of life for individuals with specific needs. Recently, the patient-driven role of designer therapeutics that compounding pharmacies occupy was overshadowed when a manmade epidemic was produced a medical catastrophe when supposedly sterile materials were contaminated with infectious agents.1

In dialysis, blood is circulated through an extracorporeal circuit for long periods of time. During this process the blood can begin to develop clot formations throughout the CVC, extracorporeal circuit, and the dialyzer itself; which causes multiple complications for the dialysis patient. In order to minimize or eliminate the

Among other approaches tried by scientists, colloidal systems like liposomes, polymeric nanoparticles etc., have shown promise but not many products have made it to the market (7). Nanoparticulate drug delivery systems are gaining much popularity in recent years. Among these, nanoparticulate drug delivery systems from biodegradable and biocompatible polymer are an interesting option for controlled drug delivery and drug targeting (8). Amongst the various drug-delivery systems, solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLCs) are potentially attractive choices due to their natural components and easily scaled-up formulation processes. In addition, their hydrophobic core provides a suitable environment for entrapment of hydrophobic drugs (9). Among the important technological advantages of nanoparticles as drug carriers are: high stability (i.e. long shelf life), high carrier capacity (i.e. many drug molecules can be incorporated into the particle matrix), feasibility of incorporation of both hydrophilic and hydrophobic substances, and feasibility of variable routes of administration (10). NLCs are kind of lipid-based nanoparticles, which has the advantages of biodegradable, brain targeting, well-recognized safety profile by drastically reducing drug-related toxicities through reduction of nonspecific biodistribution (11). NLCs consist of an unstructured solid lipid

You will be given instructions on how to care for the catheter and how it is used for the dialysis

Nurses are using technology devices such as IV monitors, computers, cardiac monitors, medication dispensing machines, portable defibrillators, and patient remote monitoring devices every day to improve patients’ quality of life. Working as a hemodialysis nurse allows me to use more advanced technology ‘hemodialysis machines and reverse osmosis devices’ while performing the hemodialysis treatment on patients. The hemodialysis machine monitors the flow of the blood while it is outside the patient and remove the waste products and the extra fluids from the body. This machine will alarm if anything goes wrong during the treatment. This machine can be considered as a safe artificial kidney that help people with kidney failure or impairment to sustain their

Many molecules, particularly peptides and polypeptides are physically embedded in polymers to create a complex network of interconnecting pores through which the drug could subsequently diffuse. The pore structure and polymer composition is controlled in order to design systems that release the drug at nearly any rate and for nearly

route. It may be in the form of capsules, powders or tablets. There are some things that may hamper the process of absorption, such as different types of medications being used at the same time. For example, some antibiotics are not absorbed

Another possibility is the process of disguising medically active molecules with lipophilic molecules that allow it to better sneak through the bbb, this is known as the pro-drug method. Another idea similar to the pro-drug method is peptide masking which masks the drugs chemical composition by masking a peptide's (a compound consisting of two or more amino acids linked in a chain) Characteristics by combining with other molecular groups that are more likely to pass through the bbb. An example of this is using a cholesteryl molecule instead of cholesterol that serves to conceal the water soluble characteristics of the drug. One of the most promising drug delivery systems is using nanoparticle delivery systems. These are systems where the drug is bound to a nanoparticle capable of traversing the bbb. The most promising compound for the nanoparticles is Human Serum Albumin (the most abundant protein in human blood plasma). The main benefits of this are that particles made of HSA are well tolerated and do not have any serious sided

On the completion of the seminar students gain the knowledge regarding hemodialysis and peritoneal dialysis and will utilize this knowledge with a positive attitude.

There are many new ways that are currently being used to improve the oral bioavailability of protein therapeutics. One way is to create microspheres of the product. This can increase bioavailability of the oral route. There are some drugs that are have microsphere technology but no FDA approved oral microspheres peptides. There are a few drug products that have been microencapsulated, Micro-K, Raloxifene Hydrochloride, and insulin. The Micro-K is an FDA approved drug product and it provides an extended release oral dosage form that some patients prefer. It releases potassium slowly in the GI tract like other extended release forms.

Hemodialysis (HD) is one of several renal replacement therapies used for the treatment of end stage kidney disease (ESKD) and kidney failure. Dialysis removes excess fluids and waste products and restores chemical and electrolyte balance. HD involves passing the patient’s blood through an artificial semipermeable membrane to perform the filtering and excretion functions of the kidney. One important step before starting regular hemodialysis sessions is preparing the vascular access; ideally, a vascular access should be placed weeks or months before you start dialysis. The