Adverse Drug Events

Each year, roughly 1.5 million adverse drug events (ADEs) occur in acute and long-term care settings across America (Institute of Medicine [IOM], 2006). An ADE is succinctly defined as actual or potential patient harm resulting from a medication error. To expound further, while ADEs may result from oversights related to prescribing or dispensing, 26-32% of all erroneous drug interventions occur during the nursing administration and monitoring phases (Anderson & Townsend, 2010). These mollifiable mishaps not only create a formidable financial burden for health care systems, they also carry the potential of imposing irreversible physiological impairment to patients and their families. In an effort to ameliorate cost inflation, undue detriment, and the potential for litigation, a multifactorial approach must be taken to improve patient outcomes. Key components in allaying drug-related errors from a nursing perspective include: implementing safety and quality measures, understanding the roles and responsibilities of the nurse, embracing technological safeguards, incorporating interdisciplinary collaborative efforts, and continued emphasis upon quality control.

When it comes to medication errors several things may occur such as adverse drug event, unexpected deterioration, and even death in severe cases. AHRQ (2015) states, “an adverse drug event (ADE) is defined as harm experienced by a patient as a result of exposure to a medication, and ADEs account for nearly 700,000 emergency department visits 100,000 hospitalizations each year.” There are many ways that errors may occur such as dispensary errors, prescription errors

Adverse drug events are estimated to cause more than 1 million emergency department visits and 125,000 hospital admissions, affecting approximately 1.9 million hospital stays each year.

Medication errors are focused on: terms and definitions; incidence of and harm; risk factors; avoidance; disclosure, legalities & consequences (Wittich, Burkle & Lanier, 2014). Medication errors categories have been developed by the American Society of Health-System Pharmacists (ASHP). Examples of these categories are based on prescribing, omitting drugs not administered, timing, unauthorized drug, wrong dosage, wrong preparation, expired drug, not using laboratory data to monitor toxicity (Wittich, Burkle & Lanier, 2014). Additionally, this article examines in depth common causes leading to medication errors, drug nomenclature, similar sounding drugs, unapproved abbreviations and handwriting, medical staff shortages and manufacturer medication shortages. Even though this article provides an informative overview for physicians, other allied health personnel may benefit too. This is valuable knowledge for the health care professional not just physicians in order to provide safe care for their

With the growing reliance on medication therapy as the primary intervention for most illnesses, patients receiving medication interventions are exposed to potential harm as well as benefits. Medicines have proven to be very beneficial for treating illness and preventing disease. This success has resulted in a dramatic increase in medication use in recent times. Unfortunately, this increase in use and expansion of the pharmaceutical industry has also brought with it an increase in hazards, error and adverse events associated with medication use.

Adverse drug events are the sixth leading cause of death in the United States and represent a significant financial burden to healthcare institutes at an estimated cost of $5.6 million per hospital per year (Meguerditchian N, Krotneva, Reidel, Huang, & Tamblyn, 2013). According to The Joint Commission (2006), medication reconciliation is the process of comparing a patient’s medication orders to all of the medications the patient has been taking. This reconciliation is done to identify and resolve medication discrepancies, which are unintended or unexplained

Medication errors are a major issue affecting patient safety in hospitals, which can create deadly consequences for patients. It is crucial to identify and analyzed medication errors so healthcare professionals can pinpoint why medication errors occur and provide insight into how to prevent or reduce them.

In 1999, the Institute of Medicine (IOM) “Too Err is Human” estimated 98,000 deaths yearly due to medical error. Many of the errors are the result of adverse drug events, most of which occur during the prescribing and administration stages of medication administration (Guo, Iribarren, Kapsandoy, Perri, and Staggers, 2011). These errors are a significant cause of morbidity and mortality in hospitalized patients. One report estimates that when all types of errors are accounted for, every hospitalized patient can expect on average one type of medication error per day and during 2006, adverse drug events resulted in approximately 400,000 cases of error at a cost of over $3.5 billion (pp. 202-224). Studies have demonstrated a

Medication error is defined as the following by the National Coordinating Council for Medication Error Reporting and Prevention: “any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of health care professional, patient, or consumer. Such events may be related to professional practice, health care products, procedures, and systems, including prescribing; order communication; product labeling; packaging, and nomenclature; compounding; dispensing; distribution; administration; education; monitoring; and use” (Anthony, Wiencek, Bauer, Daly, & Anthony, 2010). Medication errors cause increased length of patient hospitalization and morbidity and mortality (Pape

“According to the Institute of Medicine’s Preventing Medication Errors report, the average hospitalized patient is subject to at least one medication error per day” (Barnsteiner, 2008, p. 2-459). A patient’s home medication regimen is frequently continued during hospitalization. It is often found that during the process of interviewing a patient to collect all relevant data associated with their medication history, over 60% of inpatients had at least one error on their prior to admission medication list (Salanitro et al., 2012). The many challenges and current inability to accurately identify medications taken at home can lead to potential adverse events. “An adverse drug event (ADE) is defined as harm experienced by a patient as a result

It is revealed that more mistakes are made in prescription and these mistakes associated with adverse drug reaction (ADR). To avoid prescription mistakes, in some health care settings pharmacist take that responsibility of correcting medication errors related with wrong drug, wrong dose, and prescription of allergic

Medication errors are a reoccurring issue that has plagued the medical field since the beginning of drug administration. In order to understand how to handle medication errors, one must first understand what a medication error is. The concept of medication error can be defined as: “any preventable event that may cause or lead to inappropriate medication use or harm to a patient” (Kee, 2012, 125). Examples of medication errors include: misreading a patient’s medical file, not clarifying illegible prescriptions, an incomplete patient assessment, confusing look-alike and sound-alike medications, and lack of better understanding if a medication can be crushed or split. To better understand medication errors and medication safety one must understand the impact it can have on the medical community and patient care, ways to prevent medication errors, and what should be done in a situation where a medication error has occurred.

Adverse Drug Events or an ADE is defined by the U.S. Department of Health and Human Services as an injury resulting from medical intervention related to a drug (U.S. Department of Health and Human Services , n.d.). Adverse drug events have been a rising issue in the healthcare field. According to John Hopkins Medicine, medical errors are the third leading cause of death in the United States (Daniel, 2016 ). Up to sixty percent of the reported adverse drug events are preventable (Daniel, 2016 ). There is no denying that there will continue to be adverse drug events, but there are different ways to mediate the possibility of preventable.

Medication errors are not only due to miscommunication, but also due to prescribing an incorrect dosage, a potential adverse drug interaction, or a potentially fatal allergy to a medication. According to the AHRQ, “An adverse drug event (ADE) is defined as harm experienced by a patient as a result of exposure to a medication, and ADEs account for nearly 700,000 emergency department visits and 100,000 hospitalizations each year” (Agency for Healthcare Research and Quality, 2015). An EHR acts essentially as a second pair of eyes, ensuring that the prescription medication for the patient is correct. “With 76% of Americans over age 60 taking two or more prescription drugs and 37% taking five or more, health IT can improve patient safety by evaluating potential drug-drug interactions and compensating for human errors in dosing” (Consumer Partnership for E-health, 2013). Drug interactions may decrease the effectiveness of a medication, increase the serious, adverse side effects of a medication, and more importantly increase the level of toxicity a certain drug. For example, Bromocriptine is a drug used to treat menstrual problems, growth hormone production, Parkinson’s disease, and Type 2 Diabetes. Pseudoephedrine (commonly known as Sudafed) is used to treat congestion or a sinus infection; however, when the two drug are used in conjunction, “the interaction can lead to severe peripheral vasoconstriction, ventricular tachycardia, seizures, and possibly death” (Consumer

The National Patient Safety Agency (NPSA 2010), defines a drug error as ‘any preventable event that may cause or lead to inappropriate use of patient harm. Although not all drug errors have lead to patient harm it is important to recognise that if a mistakes has been