Age Related Changes

Also, three primary structural components of the dermis, collagen, elastin and GAGs have been the subjects of the majority of anti-aging research and efforts for aesthetic-anti-aging strategies pertaining to the skin, from “anti-wrinkle creams” to various filling agents.

The integumentary system establishes a barrier between the inside of the human body and the outside world. The purpose of this system is to provide protection from the external environment, sensation in terms of pressure, pain, and temperature, production of vitamin D after exposure to ultraviolet light from the sun, temperature regulation so as to not overheat the body, and excretion through means of sweating (Martini, Nath, & Bartholomew, 2011). The skin is able to provide the body with all of the aforementioned features because of its composition. The skin itself is made up of two layers: the epidermis and the dermis.

Squamous Cell Carcinoma is a common skin cancer of the outer and middle layer of epidermis caused by excessive ultraviolet radiation exposure from sources such as tanning beds and the sun. This form of Carcinoma is most commonly found on areas of the body affected by prolonged exposure such as the face, hands, arms, legs, and neck. Other factors can put patients at higher risk of developing Squamous Cell Carcinomas such as age, fair skin, long term chemical and radiation exposure, and autoimmune deficiency.

Squamous cell carcinoma (SCC) is a locally invasive tumor of the epidermal keratinocytes. The skins upper layers, also known as the epidermis, is composed of squamous cells, when they become abnormal, they grow uncontrollably. SCCs appear as scaly red patches, open sores, elevated growth with a central depression. If untreated, they grow and either become disfigured or die. SCC is caused by extensive exposure to UV light that comes from the suns rays over a long period of time. They may occur on all areas of the body but are usually found on areas that are most exposed to the sun on a daily basis. SCC is normally treated with surgical excision with wide margins of skin that appears normal to ensure that the tumor has been successfully removed.

This skin has a way, however, of healing itself. It has the ability to make new skin cells that rise to the surface and push the dead skin cells off the beaten path. Alongside the awful contaminations that come from the environment are microscopic organisms living on the surface trying to breakout and scar your radiant skin. Nevertheless, the skin is delivering sebum, a skin oil, which helps us to sustain amid the icy climate

Sweat glands and fatty layers in the process of regulating body temperature in mammals. When the external temperature is high, sweat glands release bodily fluids combined with sodium to keep the body temperature from accelerating and exceeding the normal temperature. When the outside temperature is low, fatty layers on the skin act as insulation, trapping heat and keeping it from leaving the body. The dermis is the layer of skin under the epidermis, and it's made up mostly of soft tissue such as collagen, elastin and fibrillin these are tissues that make your skin elastic and flexible yet strong and structurally stable. The dermis controls body temperature through the production of sweat and the control of evaporation the process known as insensible

One of the amazing facts you would have probably learned about the human body as a kid was that our skin is our largest organ. Our skin is covers reach of our body, and it is maybe the most pleasing organ to our eyes as we would most likely look like masses of fibrous muscles and fat without it. It also serves another purpose besides covering up all the nasty and messy inner guts of our bodies. We may not be able breath solely through our skin like an amphibian, but its purpose key to our ability to live. Our skins protects us the major factor in our environments, changes according to those factors and ultimately affects our overall health at an individual level.

This causes decreased antifungal, decreased antibacterial, decreased lubrication, more water loss, a decreased ability to block caustic and toxic irritants. Decreased sebum in the skin results in skin that is not as supple, less resilient, and predisposing skin to dryness, cracking, and wrinkling; 2) sweat glands are less active, which affects temperature regulation, hydration, and the excretory function of sweat glands, with decreased sweat, the excretion of urea, water, ammonia, and uric acid will be affected. Loss of sweat glands affects the body’s ability to cool itself (Patton & Thibodeau, 2013). Other changes include: 1) decreased in the number of cells, such as melanocytes, causing less UV protection, decreased Langerhans cells, which normally initiate an immune response in the epidermis, decreased Merkel cells, which are touch

This layer of skin is made up of two sub-layers, the papillary layer and the reticular layer. Additionally, the dermis layer of skin houses nerve endings, sweat gland, sebaceous glands, hair follicles and blood vessels which work together to regulate the body’s temperature. Nerve endings function to allow us to sense pain, touch, pressure, and temperature, while sweat glands produce sweat in response to heat and stress. The sebaceous glands, which secrete oil into hair follicles to moisten the skin and act as a barrier against foreign substances. Together the papillary layer and the reticular layer provide our skin with its flexibility and strength. (SEER Training Modules,

Physiological changes occur with aging in all organ systems. The cardiac output decreases, blood pressure increases and arteriosclerosis develops. The lungs show impaired gas exchange, a decrease in vital capacity and slower expiratory flow rates. The creatinine clearance decreases with age although the serum creatinine level remains relatively constant due to a proportionate age-related decrease in creatinine production. Functional'changes, largely related to altered motility patterns, occur in the gastrointestinal system with senescence, and atrophic gastritis and altered hepatic drug metabolism are common in the elderly.

The human body is a complex system that consists of several subsystems that all work together and help keep it functioning properly. The integumentary system is by far the largest organ of the body, and it is made up of the skin, hair, nails, sebaceous glands, and sweat glands. This system helps provide and structure for the body, and it is considered the body’s first line of defense against foreign and infectious organisms. Some of its other functions include helping the body maintain and regulate body temperature, sensing changes in the environment, supporting the removal of waste products, and aiding in the production of vitamin D.

The functions of the integumentary system are far more important than most people think. Perhaps it is commonly known that this system, known as the skin, keeps the body together and protects the inner aspects of the body from harm, or cools the body. Those functions are overly simplified and only a fraction of the role this system plays in maintaining the balance, also known as homeostasis, of the body. It can be said that this system is the first line of defense or regulation. It provides these functions: resistance to trauma and infection, barrier functions, Vitamin D synthesis, sensation, and thermoregulation to fill its role (Saladin, Sullivan, & Gan, 2015, p. 177- 178).

Because it borders with the environment, skin plays a vital immunity function in defending the body against bacteria and extreme loss of water.

Under the Dermis, there is a layer of adipose tissue which is called the Subcutaneous layer.This layer helps to maintain the human body temperature stable. This layer of fat acts like a pathway for nerves and blood vessels that go from the Dermis to the muscles. Also, it helps protect and prevents muscle and bones from

“The skin covers the entire external surface of the human body and is the principal site of interaction with the surrounding world.”-Bardia Amirlak. Everyday the skin comes in contact with many different specimens, toxins, bacteria, and environmental situations. It feels many different sensations, and changes. Also, the skin reacts in certain ways to certain situations accordingly within a millisecond. The skin or integument system is composed of many different sections and accessories, functions for multiple outlets, and falls at risk of disease everyday.