Aging And Genetics Play Developing A Cognitive Disease

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

Alzheimer’s is the most common form of dementia. “Dementia is a general term that describes a group of symptoms-such as loss of memory, judgment, language, complex motor skills, and other intellectual function-caused by the permanent damage or death of the brain 's nerve cells, or neurons.” Alzheimer’s is not a part of aging even though increasing age is a risk factor but Alzheimer’s occurs in people 65 and older. Alzheimer’s worsens over time. In the early stages memory is lost and then gradually goes to where they can’t hold a conversation or remember their surroundings.

Alzheimer’s disease effects hundreds of thousands of older adults. Research has been done and a cure is being searched for, but so far there is no way to cure it. There are treatments for Alzheimer’s that may help, but the cure is slow coming and few things have been learned about it. Older persons who experience the disease can experience a wide array of effects such as confusion, depression, violent tendencies, and many other things of that nature. There are different stages of the mental sickness, from minor, to severe. Different research states that the more schooling you have the, the less likely you are to develop Alzheimer’s, it may also be genetic and passed down through generations.

Alzheimer’s disease effects many families throughout the world and many of it causes and effects are unknown. Alzheimer’s disease is defined as a progressive mental deterioration disease that can occur in middle to old age, due to generalized degeneration of the brain. Alzheimer’s disease is generally known for its slow decrease in overall cognitive function but there are many different factors that go into the formation and spreading of any disease. Just like other diseases Alzheimer’s disease can have many potential causes and recent studies have shown that there may be more to uncover about this relatively mysterious disease.

Scientists are unable to conclude on what causes Alzheimer’s disease. An early stage of Alzheimer's is usually caused by some form of genetic mutation. Late stages of Alzheimer's occurs due to extended periods of time with brain dysfunctions. The causes probably include a combination of genetic, environmental, and lifestyle factors (CB). Most cases of Alzheimer’s is found in geriatrics aged 65 or older, however a small amount of cases are found in younger people (CA). Conditions such as heart disease, stroke, and high blood pressure are shown to increase the chances of having Alzheimer’s

Alzheimer’s disease (AD) is a slow-progressing neurodegenerative disease that has no cure and most often affects people over the age of sixty-five. Neurodegeneration is characterized by the loss of function in the central nervous system due to degeneration of neurons found mostly in the brain. The most recent data from the Center for Disease Control and Prevention shows that AD is the sixth-leading cause of death in the United States. The cause of Alzheimer’s is still not completely understood, but the current theory is that it appears to be genetic in which many genes are involved. AD is also the most common form of dementia and accounts for 60-80% of cases (Alzheimer’s Association 2016). Dementia is not a disease itself, but instead is characterized by a group of symptoms that is caused by brain disease or injury in which memory, personality, and reasoning skills are affected.

Alzheimer’s disease is a neurodegenerative of the brain that causes dementia, which is a loss in memory. Besides it being a neurodegenerative disease, many other conditions can cause dementia. Another kind of dementia is nutritional dementia, also called Wernicke-Korsakoff syndrome, or another which is alcohol syndrome, and it is caused by a lack of vitamin B1. Alzheimer’s disease usually appears in people over sixty-five years old. However, some cases of Alzheimer’s disease can happen at an early age of forty to fifty years old. This is called early-onset Alzheimer’s disease. It is caused by gene mutations that can be passed from parent to child. The most common form of late-onset Alzheimer’s disease is caused by the inability to clear amyloid-beta protein from the brain. Cerebrospinal is what help clear out the bad things in the brain, like amyloid-beta.

Scientists believe that the combinations of genetics, environmental factors, and lifestyle play a huge part in Alzheimer’s disease. Scientists are learning that age-related changes may harm neurons. These changes include shrinking of the brain, and inflammation. In early-onset genetic mutation is usually the cause, and people thirty to sixty represent less than five percent of people with Alzheimer’s disease. In late-onset

Alzheimer's can occur from a number of things, but the number one cause is genetically based. Alzheimer's is caused by mutations or abnormalities, this permanent change occur in one or more specific genes. Alzheimer’s can be one of several different single gene mutations on chromosomes 21, 14, and 1. These mutations can cause abnormal proteins to form, which then disrupts brain activity. These changes affect how the nerve cells and the brain cells communicate with each other. There are a number of contributing factors such as age, head trauma, lifestyle, environment, and many others. Alzheimer's studies are also beginning to show a link between Alzheimer's and cardiovascular conditions, inflammation, and

Experts believe that Alzheimer’s, like other chronic diseases, develops under multiple risk factors rather than a single one. The greatest factor is increasing age, where the majority of people with Alzheimer’s are 65 or older, but people in

Alzheimer’s disease is a very slowly progressive disease that occurs inside the brain in which is characterized by damage of memory. Also this type of disease can lead into interruption in language, problem solving, planning and perception. The chance of a person developing Alzheimer’s disease increases enormously after the age of 70 (Crystal, 2009). Also people who are over the age of 85 have over a 50 percent chance of developing Alzheimer’s disease. This type of disease is not at all normal in the aging process and is also not something that happens out of no where in a person’s life.

Most of the patients with Alzheimer’s disease are people of age 65 years and above. It is therefore, believed that age is an environmental factor that increases the risk of Alzheimer’s development. Even though it is not proven scientifically, the statisticians have reported half of the people over the age of 80 having Alzheimer’s disease (Causes and Risk Factors for Alzheimer’s Disease., n.d.). Other risk factors that may lead to the disease development are; smoking, Hypertension, accumulation of cholesterol in the body, poorly controlled diabetes, lack of social engagement, lack of exercise and mild cognitive impairment.

Although the primary onset of AD is old age, younger adults are also at risk. Late-onset Alzheimer’s disease affects the elderly and geriatric community. This influx of late-onset Alzheimer’s affects about 5% of people between the ages of 65 to 74 and almost 50% of people over 85 years old. Early-onset is another stage of this disease; occasionally affecting people younger than the age of 40. There is a negative genetic predisposition correlation for those whom suffer from early-onset dementia having family members related to be much more likely to develop AD, than those related to people with late-onset AD. Research of early-onset AD mainly focuses on genetic factors. Physiological research states genetics, environmental factors, or a combination of both cause AD. (Evans, George, 2000).

According to the National Institute of Health, Alzheimer’s is a degenerative disease of the brain. It features progressive loss of the brain’s nerve cells over time which results in a decline in thinking processes and other cognitive abilities. Alzheimer’s disease affects 15 million people around the world, and 4.5 million persons in the United States, alone. At least one in 10 persons over the age of 65 will suffer from Alzheimer's and almost half of those over the age of 85. This number is set to go up considerably as the Baby Boomer generation ages.

Alzheimer’s disease can be caused by a combination of how a person lives, from their genetics, and the environment that person is in. People who are affected with disease have fewer brain cells and fewer connections with the healthy cells than a healthy brain. When doctors look under the microscope for problems with the brain tissues, the doctors will see two different things. They will see plagues which are clumps