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Agrobacterium Causes Crown-Gall Disease?

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We are just going to focus our discussion on A.tumefaciens.
Agrobacterium causes crown-gall disease, which is a neoplastic development that occurs due to the transfer of a DNA (T-DNA) portion from the bacterial tumor-inducing (Ti) plasmid to the host cell. The molecular machinery required for T-DNA transport into the host cell contains proteins that are encoded by the bacterial chromosomal virulence genes (chv) and by the Ti-plasmid virulence genes (vir). Although we know a lot about the functions of Agrobacterium Vir proteins, and about their role in T-DNA production and processing inside the bacterial cells, less is known about the system by which the T-DNA goes into the host cell. Only in the recent times we have begun exploring the functions
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