Altepalase Research Paper

Strokes are caused by a block in the blood supply to the brain which causes a decrease in oxygen and delivery of other important supplies which facilitate proper functioning. Fifteen million cases are reported worldwide annually, although not all of these cases are mortalities, the large prevalence of strokes ranks it as the fourth leading cause of death in the United States. (Figueroa) Because of the time sensitivity associated with the lack of resources to the brain, strokes are considered a medical emergency and early recognition of symptoms can help decrease the amount of damage caused . Although strokes do not always cause death, strokes most often leave the individual with some physical and cognitive impairment.

An ischemic stroke is typically caused by a thrombosis, which is a blood clot or an embolism, when the blood clot detaches and infiltrates the blood stream.

To have their symptoms diagnosed, a person must first seek medical treatment. Only 20-25% of patients who are admitted to the hospital with a stroke arrive in the emergency department within 3 hours of the onset of symptoms (3). Once a doctor is able to determine what kind of stroke has occurred, it is important the appropriate medicine be given. If the wrong medicine were given to treat a stroke victim, it could result in death. Treatment for an ischemic stroke will focus mainly on restoring blood flow

It is important that the type of stroke is diagnosed quickly to reduce the damage done to the brain and also to determine the right type of treatment because one treatment for one kind of stroke can be harmful to someone who has had a different kind. A number of different medications may be given at the hospital to help break up the clot and prevent the formation of new clots. For Ischemic stroke the treatment can begin with drugs to break down clots and prevent further ones from forming. Aspirin can be given, along with an injection of a tissue plasminogen activator (TPA). TPA works by dissolving clots but it needs to be injected within 4.5 hours of stroke symptoms once they have presented themselves. Hemorrhagic stroke treatment can begin with drugs being given to reduce the pressure in the brain, overall blood pressure, prevent seizures and prevent sudden constrictions of blood vessels.(http://www.mayoclinic.org/diseases-conditions/stroke/diagnosis-treatment/treatment/txc-20117296) Because strokes are life-changing events that can affect a person both physically and emotionally, temporarily or permanently. After a stroke,

This loss involves a 40 year old female from Japan with a history of alcohol abuse. On 01/21/13, the claimant arrived at Kapiolani Medical Center for Women & Children Clinic (KMC) with complaints of slurred speech and mild paralysis of the right upper and lower extremities. The claimant was examined by physician, Dr. Lee who diagnosis restriction of oxygen due to decrease blood flow (stroke). Dr. Lee consulted with neurologist, Dr. Pearce at Straub Medical Hospital (SMH) and suggested TPA IV treatment to dissolve blood clots while improving blood flow (time sensitive treatment required within 4.5 hours of diagnosis of stroke). Since KMC was not equipped to provide the TPA treatment

The kingdom of Altheras had been a small but prosperous and independent kingdom. They had favored political independence, instead forging strong trade relationships and selling there many resources and products made out of those resources to other nations. There military was a combination of a traditional military with long-standing customs who were mainly put to use for guarding the trading caravans and ships and performing military parades and honor guards on ceremonial occasions like a coronation or a royal funeral.

Treatment for this condition depends on the cause. It may involve taking blood-thinning medicine, such as aspirin, to reduce the risk of stroke. It may also involve lifestyle changes, such as:

- Coagulation inhibitors and Fibrinolysis : to Localize thrombus on injury and Prevent new thrombus formation.

In response to the phenomenon of ischemic stroke, a number of treatments and interventions have emerged. Tissue plasminogen activator (tPA) is widely affirmed in the literature as the most effective treatment of ischemic stroke at the present time (CITE ). This intervention, while effective, carries many question risks.marks, however. It is not well understood, for example, how long after ischemic stroke onset that tPA intervention is effective

There are many ways someone can prevent a stroke and it is all about recognizing certain health issues and being as healthy as possible. Diet and exercise are one of the main ways a person can prevent a stroke, especially if they are overweight. Eating fatty foods can increase the amount of fat deposits in the body which can eventually lead to clotting. Being overweight tends to result in high blood pressure or diabetes which are both main causes of a stroke. Controlling your blood pressure, the type and amount of food you consume, and exercising can be very preventative from having a stroke. It is also important to know your risks. If you know people in your family have high blood pressure, have had blood clots, or any heart problems, it is

Stroke previously known as Cerebrovascular accident is well-defined as ‘an abrupt cessation of cerebral circulation in one or more of the blood vessels distributing the brain. Due to the interruption or diminish of oxygen supply causes serious damage or necrosis in the brain tissues (Jauch, Kissella & Stettler, 2005). There is a presence of one or more symptoms such as weakness or numbness or paralysis of the face, arm or leg, difficulty speaking or swallowing, dizziness, loss of balance, loss of vision, sudden blurring or decreased vision in one or both eyes and headache. Stoke is categorised into two types, Ischaemic and haemorrhagic

Depending on the most likely cause of your stroke, your doctor may advise specific medication or consider surgery to remove fatty deposits in your carotid artery.

In a second type of epilepsy, known as generalized seizure, tonic clonic, grand mal, or convulsion, the whole brain is involved. This type of seizure is often characterized by an involuntary scream, caused by contraction of the muscles that control breathing. As loss of consciousness sets in, the entire body is gripped by a jerking muscular contraction. The face reddens, breathing stops, and the back arches. Then, alternate contractions and relaxations of the muscles throw the body into sometimes violent agitation such that the person may be subject to serious injury. After the convulsion subsides, the person is exhausted and may sleep heavily.

Tissue plasminogen activator is a fibrinolytic drug which is used to treat thromboembolic disorders, such as ischaemic strokes. These agents initiate secondary fibrinolysis to occur; altering the haemostatic capability. The primary purpose of this agent is to clear occluded blood vessels within the systemic circulation (Bryant & Knights 2011, pp.534-536).

Thrombolytic medications are approved for the immediate treatment of stroke and heart attack. The most commonly used drug for thrombolytic therapy is tissue plasminogen activator (tPA), but other drugs can do the same thing.